Neuroscience Chapter 5 Quiz

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Questions and Answers

What is the primary role of kinesin in axoplasmic transport?

  • It moves substances from the cell body to the terminal buttons. (correct)
  • It regulates the shape of the neuron.
  • It generates electrical impulses within the neuron.
  • It moves substances from terminal buttons to the cell body.

Which part of the neuron is primarily associated with integrating signals?

  • Axon hillock (correct)
  • Terminal buttons
  • Dendrites
  • Cell nucleus

How do neurotransmitters interact with the postsynaptic neuron?

  • They bind to receptors and then diffuse away. (correct)
  • They trigger action potentials directly.
  • They are absorbed by the postsynaptic neuron.
  • They enter the postsynaptic neuron.

What is an example of retrograde axoplasmic transport?

<p>Dynein transporting signals from the terminal buttons to the cell body. (B)</p> Signup and view all the answers

What structural component of the neuron contributes to its shape?

<p>Cytoskeleton (C)</p> Signup and view all the answers

Which type of transport is primarily responsible for moving proteins produced in the cell body to the terminal buttons?

<p>Anterograde transport (B)</p> Signup and view all the answers

What happens to dendritic spines over time?

<p>They can change rapidly or remain stable. (B)</p> Signup and view all the answers

What is the function of channel proteins in the neuron's cell membrane?

<p>To allow selective passage of certain molecules. (C)</p> Signup and view all the answers

What triggers the action potential in a neuron?

<p>Threshold of excitation (B)</p> Signup and view all the answers

What force is responsible for the movement of molecules from regions of high concentration to low concentration?

<p>Diffusion (A)</p> Signup and view all the answers

What type of ion is represented by Na+?

<p>Cation (C)</p> Signup and view all the answers

Which ion is predominantly found in the extracellular fluid?

<p>Chloride ion (Cl-) (A)</p> Signup and view all the answers

What balances the diffusion of potassium ions (K+) outside the axon?

<p>Electrostatic pressure pulling K+ inside (C)</p> Signup and view all the answers

What is true about the A- ion in relation to the neuronal membrane?

<p>It cannot pass through the membrane (B)</p> Signup and view all the answers

How does electrostatic pressure affect cations and anions in the neuron?

<p>It attracts cations away from regions with excess cations (B)</p> Signup and view all the answers

Which statement correctly describes the concentration of K+ ions in the axon?

<p>They are concentrated inside the axon (D)</p> Signup and view all the answers

What characterizes a bipolar neuron?

<p>It has one dendrite and one axon. (B)</p> Signup and view all the answers

Which type of neuron is primarily responsible for transmitting sensory information?

<p>Bipolar neurons (D)</p> Signup and view all the answers

What is a primary role of motor neurons?

<p>To control the contraction of muscles. (B)</p> Signup and view all the answers

How do local interneurons differ from relay interneurons?

<p>Local interneurons form circuits with nearby neurons. (B)</p> Signup and view all the answers

What structural components are essential for synapse function?

<p>Presynaptic membrane, synaptic cleft, and postsynaptic membrane. (D)</p> Signup and view all the answers

What initiates the release of neurotransmitters from synaptic vesicles?

<p>Electrical activity in the presynaptic neuron. (C)</p> Signup and view all the answers

What is the function of postsynaptic receptors?

<p>To capture and react to neurotransmitters. (B)</p> Signup and view all the answers

Which of the following best describes multipolar interneurons?

<p>They have no axon. (D)</p> Signup and view all the answers

What role do sodium-potassium pumps play in the neuron?

<p>They maintain the concentration gradient by pumping Na+ out and K+ in. (D)</p> Signup and view all the answers

Which statement correctly explains the movement of Na+ ions across the neuronal membrane?

<p>Both diffusion and electrostatic pressure push Na+ inward. (C)</p> Signup and view all the answers

What is a significant characteristic of voltage-dependent ion channels?

<p>They can be opened by changes in membrane potential. (A)</p> Signup and view all the answers

What effect does the influx of Na+ ions have on the membrane potential during an action potential?

<p>It leads to a rapid increase in membrane potential. (A)</p> Signup and view all the answers

How does the sodium-potassium pump affect the concentration of K+ ions inside the neuron?

<p>It increases the intracellular concentration of K+ ions. (D)</p> Signup and view all the answers

What is the primary reason why Na+ ions are more concentrated outside the axon?

<p>Sodium-potassium pumps actively transport Na+ ions out of the axon. (C)</p> Signup and view all the answers

What occurs when the membrane potential reaches the threshold of excitation?

<p>Sodium channels open, allowing Na+ to rush into the axon. (D)</p> Signup and view all the answers

What percentage of a neuron's metabolic resources is used by sodium-potassium transporters?

<p>40% (C)</p> Signup and view all the answers

What distinguishes action potentials from postsynaptic potentials?

<p>Action potentials are all-or-none and not decremental. (D)</p> Signup and view all the answers

What is spatial summation in neural integration?

<p>The integration of PSPs from different locations on the cell body. (C)</p> Signup and view all the answers

How are postsynaptic potentials terminated?

<p>By reuptake and enzymatic deactivation. (B)</p> Signup and view all the answers

What is presynaptic inhibition?

<p>Decreased neurotransmitter release due to axoaxonic synapse activity. (D)</p> Signup and view all the answers

Which type of synapse occurs between two terminal buttons?

<p>Axoaxonic synapse. (D)</p> Signup and view all the answers

What role do gap junctions play at dendrodendritic synapses?

<p>They facilitate electrical connections without neurotransmitter involvement. (A)</p> Signup and view all the answers

Which of the following describes temporal summation?

<p>Summation of postsynaptic potentials occurring in rapid succession. (B)</p> Signup and view all the answers

What happens during the reuptake of neurotransmitters?

<p>Transporter molecules remove neurotransmitters from the synaptic cleft. (C)</p> Signup and view all the answers

What mechanism allows for faster conduction of action potentials in myelinated axons?

<p>Saltatory conduction (D)</p> Signup and view all the answers

What is the consequence of sodium channels being concentrated at the nodes of Ranvier?

<p>Decreased energy consumption by the axon (A), The action potential gets retriggered at the nodes (D)</p> Signup and view all the answers

Which feature of cerebral neurons is NOT accounted for in the Hodgkin-Huxley model?

<p>Active conduction of action potentials in dendrites (B), Ability to fire action potentials without input (C), Variability in action potential characteristics (D)</p> Signup and view all the answers

What is the primary role of small synaptic vesicles in terminal buttons?

<p>Contain molecules of a neurotransmitter (B)</p> Signup and view all the answers

How does myelination affect the sodium balance in an axon?

<p>It decreases the amount of sodium that must be pumped out (C)</p> Signup and view all the answers

What kind of conduction do non-myelinated axons primarily utilize?

<p>Continuous conduction (C)</p> Signup and view all the answers

How does the firing rate of an axon change in response to varying light intensities?

<p>The axon fires more action potentials for brighter light (D)</p> Signup and view all the answers

In what way do some cerebral neurons differ from typical action potential behavior?

<p>They may not display action potentials at all (B)</p> Signup and view all the answers

Flashcards

Bipolar Neuron

A type of neuron with one dendrite and one axon, found in sensory systems such as vision.

Multipolar Interneuron

A neuron with a short axon or no axon at all, found in the brain and responsible for integrating information within a single brain structure.

Sensory Neuron

A neuron that gathers information from the environment, such as light, sound, touch, etc., and transmits it to the central nervous system (CNS).

Motor Neuron

A neuron that controls muscle movements.

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Relay Interneuron

A neuron that lies entirely within the CNS and connects different brain regions.

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Synapse

A specialized junction between two neurons where communication happens.

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Neurotransmitters

Chemical messengers released by presynaptic neurons that transmit signals to postsynaptic neurons.

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Postsynaptic Receptors

Protein molecules on the postsynaptic membrane that bind to neurotransmitters. They mediate the effects of neurotransmitters.

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Axoplasmic transport

The process of moving substances along microtubules within the axon.

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Anterograde axoplasmic transport

Movement from the cell body to the terminal buttons, carried by kinesin.

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Retrograde axoplasmic transport

Movement from the terminal buttons back to the cell body, carried by dynein.

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Axon hillock

The area where the axon originates from the cell body, responsible for integrating signals.

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Dendritic spines

Small protrusions on dendrites that can change shape, involved in communication and learning.

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Neural plasticity

The ability of the brain to change and adapt its connections.

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Ribosomes

Tiny structures inside the cell nucleus responsible for protein synthesis.

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Membrane Potential

The difference in electrical charge between the inside and outside of a neuron.

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Diffusion

The movement of molecules from an area of high concentration to an area of low concentration.

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Electrostatic Pressure

The force exerted by the attraction or repulsion of ions.

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Threshold of Excitation

The point where the electrical potential across the cell membrane reaches a threshold and triggers an action potential.

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Action Potential

A wave of electrical activity that travels down the axon of a neuron.

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Ions

Charged particles, such as sodium (Na+), potassium (K+), chloride (Cl-), and organic anions (A-), that contribute to the membrane potential.

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Axon Initial Segment

The compartment at the base of an axon where an action potential is generated.

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Sodium-potassium pump

A mechanism that actively pumps sodium ions out of the cell and potassium ions into the cell, maintaining the concentration gradient.

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Resting membrane potential

The difference in electrical charge between the inside and outside of a neuron, typically around -70mV.

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Ion channels

Specialized protein structures that allow specific ions to enter or leave the neuron. They can be open or closed, regulating ion flow across the membrane.

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Voltage-dependent ion channel

Type of ion channel that opens or closes in response to changes in membrane potential.

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Membrane permeability

The ability of a membrane to allow specific ions to pass through, determined by the number of open ion channels.

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Action Potential Frequency

The strength of an action potential is determined by how frequently it fires in a given time period.

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Saltatory Conduction

The process where an action potential jumps from one node of Ranvier to the next, increasing the speed of signal transmission.

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Nodes of Ranvier

Gaps between myelin sheaths on an axon where sodium ions (Na+) can enter, retriggering the action potential.

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Decremental Conduction

The movement of an action potential down an axon, where its strength diminishes as it travels.

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Synaptic Vesicles

Specialized pouches at the end of a neuron that contain neurotransmitters, chemical messengers involved in neuronal communication.

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Synaptic Vesicle Production and Transport

The production of synaptic vesicles, small packages containing neurotransmitters, in the Golgi apparatus and their transport to the terminal button.

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Synaptic Vesicle Recycling

The process of recycling synaptic vesicles in the terminal button.

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Postsynaptic Potential (PSP)

A type of signal that occurs at the synapse between neurons, it can be graded (vary in strength) and decremental (decrease in strength as it travels).

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Spatial Summation

The integration of multiple PSPs occurring simultaneously at different locations on the cell body of a neuron.

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Temporal Summation

The integration of multiple PSPs occurring in rapid succession at the same location on the cell body of a neuron.

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Reuptake

The process by which neurotransmitters are removed from the synaptic cleft by special transporter molecules.

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Enzymatic Deactivation

The process by which neurotransmitters are broken down by enzymes in the synaptic cleft.

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Axodendritic Synapse

A synapse that occurs between the terminal button of one axon and the dendrite or dendritic spine of another neuron.

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Axosomatic Synapse

A synapse that occurs between the terminal button of one axon and the cell body of another neuron.

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Study Notes

Neurons and the Nervous System

  • The nervous system is composed of neurons and glial cells.
  • Neurons are specialized cells for receiving, conducting, and transmitting electrochemical signals.
  • Glial cells provide support and contribute to information processing.
  • The neuron doctrine proposes that information is transmitted from one neuron to the next across synapses.
  • Neurons are 80-90 billion in the adult human brain and roughly equal numbers to glial cells.
  • External features of neurons include dendrites, cell body, axon, and axon terminals.

Anatomy of Neurons

  • Dendrites: Receive information from other neurons across synapses.
  • Cell body (soma): Contains the cell nucleus and processes the received information to determine if there is a need to send a signal.
  • Axon: A long, thin tube that leaves the cell body and serves as a conduction zone. It is covered by a myelin sheath.
  • Myelin sheath: Insulating substance that speeds the conduction of electrical signals.
  • Axon terminals (terminal buttons): Transmit signals across synapses to other cells.
  • Nodes of Ranvier: Gaps between sections of myelin in the axon.

Classifications of Neurons

  • Multipolar neuron: Many dendrites and a single axon (most common type).
  • Unipolar neuron: Only 1 process extending from the cell body, branching into input and output zones.
  • Bipolar neuron: 1 dendrite and 1 axon, common in sensory systems (e.g., vision).
  • Multipolar interneuron: Short axon or no axon, connecting circuits of neurons within a brain region.

Synapses

  • Synapses consist of a presynaptic membrane, synaptic cleft, and postsynaptic membrane.
  • Presynaptic membrane (axon terminal): Contains synaptic vesicles with neurotransmitters.
  • Synaptic cleft: A gap between presynaptic and postsynaptic neurons.
  • Postsynaptic membrane: Contains receptors for neurotransmitters.

Synaptic Transmission

  • Electrical activity in the axon causes vesicles to fuse with the presynaptic membrane and release neurotransmitters into the synaptic cleft.
  • Neurotransmitters bind to receptors on the postsynaptic membrane, causing changes in membrane potential.

Types of Neurotransmitters

  • Neurotransmitters are molecules that transmit signals across synapses. Examples are not provided.

Neuron Classifications by Function

  • Sensory neurons: Gather information from the environment (light, sound, touch etc).
  • Motor neurons: Control the contraction of muscles (facilitate movements).
  • Interneurons: Connect circuits of neurons in different parts of the CNS or within a region.

Action Potentials

  • Action potentials are bursts of rapid depolarization and hyperpolarization.
  • They begin at the axon initial segment and travel down the axon.
  • This process is all-or-none (always the same size), but rate of firing varies with the intensity of the stimulus.

Membrane Potential

  • Membrane potential is the difference in charge across the membrane.
  • Resting potential is -70 mV.
  • Action potentials are caused by changes in the movement of ions (sodium, potassium, chloride) across the membrane, driven by diffusion and electrostatic pressure.

Axoplasmic Transport

  • Anterograde transport: Movement of substances from cell body to axon terminals.
  • Retrograde transport: Movement of substances from axon terminals to cell body.

Glial Cells

  • Astrocytes are the largest glial cells. They form functional networks and control blood flow.
  • Microglia respond to damage and remove debris.
  • Oligodendrocytes myelinate axons in the CNS and Schwann cells myelinate axons in the PNS.

Neurotransmission: Direct and Indirect

  • Direct method: neurotransmitter directly opens ion channels.
  • Indirect method: neurotransmitter activates a second messenger system to open ion channels.

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