Neurophysiology: Action Potentials and Synapses

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Questions and Answers

What happens to the areas left behind as the action potential spreads down the axon?

  • They convert into neurotransmitters
  • They initiate another action potential
  • They return to their resting state (correct)
  • They become depolarized

What is the role of the synapse in neuronal communication?

  • It stores neurotransmitters until needed
  • It conducts electrical impulses directly
  • It physically connects neurons
  • It allows chemical signals to pass between neurons (correct)

Which neuron releases neurotransmitters?

  • Presynaptic neuron (correct)
  • Postsynaptic neuron
  • Sensory neuron
  • Motor neuron

Which neurotransmitter is primarily associated with muscle action and memory?

<p>Acetylcholine (B)</p> Signup and view all the answers

What effect do inhibitory neurotransmitters have on a neuron?

<p>They decrease the likelihood of firing an action potential (C)</p> Signup and view all the answers

Which neurotransmitter is primarily linked to the reward system and addiction?

<p>Dopamine (A)</p> Signup and view all the answers

What is the function of reuptake in neurotransmission?

<p>It absorbs leftover neurotransmitters for recycling (A)</p> Signup and view all the answers

What is an effect of increased levels of GABA in the central nervous system?

<p>Inhibition of neuron firing (A)</p> Signup and view all the answers

Which neurotransmitter is crucial for emotional arousal and metabolism of glucose?

<p>Epinephrine (C)</p> Signup and view all the answers

What is the primary role of excitatory neurotransmitters?

<p>To increase neuron firing likelihood (B)</p> Signup and view all the answers

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Study Notes

Action Potential and Synapses

  • Action potentials propagate along the axon while areas behind return to resting state.
  • Synapses are pivotal for neuronal communication, allowing the passing of chemical signals.
  • Neurons do not physically touch; neurotransmitters traverse the synaptic gap to transmit signals.
  • Presynaptic neuron initiates the signal, while postsynaptic neuron receives it.

Neurotransmitter Release and Function

  • Action potentials trigger terminal buttons at the axon’s end to release neurotransmitters into the synapse.
  • Vesicles fuse with the presynaptic membrane, releasing their contents into the synaptic cleft.
  • Neurotransmitters bind to receptors on the postsynaptic membrane, potentially eliciting an action in the postsynaptic cell, depending on whether an action potential is achieved.
  • Unused neurotransmitters are typically reabsorbed by the presynaptic neuron via reuptake.

Types of Neurotransmitters

  • Excitatory Neurotransmitters

    • Increase the probability of a neuron firing an action potential.
  • Inhibitory Neurotransmitters

    • Decrease the likelihood of neuron firing an action potential.
  • Acetylcholine (ACh)

    • Functions: muscle action, learning, attention, memory, REM sleep, emotion.
    • Decreased levels associated with Alzheimer’s disease.
  • Dopamine (DA)

    • Functions: movement, attention, memory, learning, emotion.
    • Excess linked to schizophrenia; deficit related to Parkinson’s disease; significant role in addiction and reward pathways.
  • Endorphins

    • Functions: mood regulation, pain relief, memory, learning, blood pressure, appetite, sexual activity.
    • Therapeutic applications in pain management.
  • Epinephrine (Adrenaline)

    • Functions: emotional arousal, memory storage, metabolism of glucose for energy release.
  • GABA (Gamma-Aminobutyric Acid)

    • Functions: learning, anxiety regulation.
    • Major inhibitory neurotransmitter in the central nervous system; tranquilizers like Valium enhance GABA's effects to reduce anxiety.
  • Glutamate

    • Functions: learning, movement, memory.
    • Key role in neural excitation within the central nervous system.

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