12 Questions
A synapse is a specialized region of communication between two ______, at least one of which is an excitable cell.
cells
In an electrical synapse, ionic current can pass directly between the two cells by means of ______ junctions, allowing AP propagation.
gap
Gap junctions are found between cardiac muscle cells, between some types of smooth muscle cells, and in some cases between ______.
neurons
Even 'fast' chemical synapses incur a synaptic delay, of perhaps 0.5 to 2 ______.
msec
The neuromuscular junction is an important model for the study of fast synaptic transmission, also referred to as ______ transmission because it involves opening ion channels directly.
ionotropic
Metabotropic transmission, which is slower, involves second messengers which may modulate ______ activity.
ion channel
All the fibres innervated by the same axon will contract together and are referred to collectively as a ______ unit
motor
Do plants have anything analogous to electrical synapses between cells in animals?
Yes
Each NMJ consists of a branching axon terminal, contained within a gutter in the muscle fibre ______
membrane
The transmitter acetylcholine (ACh) is released from a number of swellings called terminal ______ within the end-plate
boutons
The post-synaptic membrane contains, on the crests of the junctional folds, a high density of nicotinic acetylcholine receptors (NAChR), which are ligand-gated ion ______
channels
Having diffused across the synaptic cleft, one ACh molecule must bind to each of the α subunits to cause the channel to ______
open
Test your knowledge on the generation of action potentials (APs) through synapses, myogenic AP generation, and sensory receptors. Learn about the specialized regions of communication between excitable cells and the role of electrical synapses in AP propagation.
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