Neuropharmacology Quiz: Acetylcholine and Neurotransmitters

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What is the primary neurotransmitter in the parasympathetic nervous system?

Serotonin

Norepinephrine

Dopamine

Acetylcholine (correct)

What is the enzyme that facilitates the transfer of Acetyl from Acetyl CoA to Choline to produce Acetylcholine?

Choline kinase

Acetyl CoA synthase

Choline acetyltransferase (correct)

Acetyl CoA dehydrogenase

What is the purpose of the vesicle-associated transporter (VAT) in Acetylcholine synthesis?

To transport Choline into the synapse

To release Acetylcholine into the synapse

To store Acetylcholine in vesicles (correct)

To synthesize Acetylcholine

Which toxin inhibits the release of Acetylcholine?

Botulinum toxin Signup and view all the answers

What is the primary function of Choline Transporter in Acetylcholine synthesis?

To transport Choline into the synapse Signup and view all the answers

What is the result of inhibiting the active uptake of Choline?

Decreased synthesis of Acetylcholine Signup and view all the answers

What is the outcome when Acetylcholinesterase (Ache) metabolizes acetylcholine?

Muscle weakness Signup and view all the answers

Which type of cholinergic receptors are involved in slowing down heart rate and reducing contractions?

M2 receptors Signup and view all the answers

What is the role of M1 receptors in the CNS?

Slow excitation at ganglia Signup and view all the answers

What is the mechanism of action of Carbachol?

Inhibits the enzyme AChE Signup and view all the answers

Which of the following is used in the diagnosis of asthma?

Metacholine Signup and view all the answers

Which muscarinic receptors are responsible for the contraction of the ciliary muscle in the eyes?

M3 receptors Signup and view all the answers

What is the effect of Muscarine on the heart rate?

Decreases heart rate Signup and view all the answers

What is the effect of M3 receptors on the urinary bladder?

Constriction of the bladder Signup and view all the answers

What is the mode of action of Physostigmine?

Inhibits the breakdown of acetylcholine Signup and view all the answers

What is the treatment of myasthenia gravis?

All of the above Signup and view all the answers

What is the use of Edrophonium?

Diagnosis of myasthenia gravis Signup and view all the answers

Which type of receptors are involved in the regulation of cholinergic and dopaminergic neurotransmitters?

M4 receptors Signup and view all the answers