Neuropharmacology Quiz: Acetylcholine and Neurotransmitters
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Questions and Answers

What is the primary neurotransmitter in the parasympathetic nervous system?

  • Serotonin
  • Norepinephrine
  • Dopamine
  • Acetylcholine (correct)

What is the enzyme that facilitates the transfer of Acetyl from Acetyl CoA to Choline to produce Acetylcholine?

  • Choline kinase
  • Acetyl CoA synthase
  • Choline acetyltransferase (correct)
  • Acetyl CoA dehydrogenase

What is the purpose of the vesicle-associated transporter (VAT) in Acetylcholine synthesis?

  • To transport Choline into the synapse
  • To release Acetylcholine into the synapse
  • To store Acetylcholine in vesicles (correct)
  • To synthesize Acetylcholine

Which toxin inhibits the release of Acetylcholine?

<p>Botulinum toxin (D)</p> Signup and view all the answers

What is the primary function of Choline Transporter in Acetylcholine synthesis?

<p>To transport Choline into the synapse (D)</p> Signup and view all the answers

What is the result of inhibiting the active uptake of Choline?

<p>Decreased synthesis of Acetylcholine (C)</p> Signup and view all the answers

What is the outcome when Acetylcholinesterase (Ache) metabolizes acetylcholine?

<p>Muscle weakness (C)</p> Signup and view all the answers

Which type of cholinergic receptors are involved in slowing down heart rate and reducing contractions?

<p>M2 receptors (A)</p> Signup and view all the answers

What is the role of M1 receptors in the CNS?

<p>Slow excitation at ganglia (B)</p> Signup and view all the answers

What is the mechanism of action of Carbachol?

<p>Inhibits the enzyme AChE (B)</p> Signup and view all the answers

Which of the following is used in the diagnosis of asthma?

<p>Metacholine (B)</p> Signup and view all the answers

Which muscarinic receptors are responsible for the contraction of the ciliary muscle in the eyes?

<p>M3 receptors (B)</p> Signup and view all the answers

What is the effect of Muscarine on the heart rate?

<p>Decreases heart rate (C)</p> Signup and view all the answers

What is the effect of M3 receptors on the urinary bladder?

<p>Constriction of the bladder (D)</p> Signup and view all the answers

What is the mode of action of Physostigmine?

<p>Inhibits the breakdown of acetylcholine (A)</p> Signup and view all the answers

What is the treatment of myasthenia gravis?

<p>All of the above (D)</p> Signup and view all the answers

What is the use of Edrophonium?

<p>Diagnosis of myasthenia gravis (A)</p> Signup and view all the answers

Which type of receptors are involved in the regulation of cholinergic and dopaminergic neurotransmitters?

<p>M4 receptors (C)</p> Signup and view all the answers

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