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Questions and Answers
What is the primary cause of neuropathic pain?
What is the primary cause of neuropathic pain?
How would you describe the sensation of neuropathic pain?
How would you describe the sensation of neuropathic pain?
Where can damage or injury to the nociceptive nerves occur to cause neuropathic pain?
Where can damage or injury to the nociceptive nerves occur to cause neuropathic pain?
What is a common characteristic of areas affected by neuropathic pain?
What is a common characteristic of areas affected by neuropathic pain?
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What is NOT a characteristic of neuropathic pain?
What is NOT a characteristic of neuropathic pain?
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What is the primary function of ion channels present on nociceptor terminals?
What is the primary function of ion channels present on nociceptor terminals?
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What is the effect of local anesthetics on nociceptors?
What is the effect of local anesthetics on nociceptors?
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What type of nerve endings are nociceptors?
What type of nerve endings are nociceptors?
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What is the outcome of the activation of ion channels on nociceptor terminals?
What is the outcome of the activation of ion channels on nociceptor terminals?
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What is the role of nociceptors in the pain pathway?
What is the role of nociceptors in the pain pathway?
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Study Notes
Neuropathic Pain is caused by damage or injury to the nociceptive nerves – peripherally or centrally. The pain is usually described as a burning sensation and affected areas are often sensitive to the touch.
Nociceptors and Pain Pathways
- Nociceptors are free nerve endings found in the skin
- Various stimuli activate ion channels present on nociceptor terminals, acting as molecular transducers
- Activation of these ion channels leads to depolarization of nociceptor neurons, initiating nociceptive impulses
- Nociceptive impulses then propagate along pain pathways
- Local anaesthetics, such as lidocaine, can block nociceptor activity
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Description
Explore the causes and characteristics of neuropathic pain, including damage to nociceptive nerves and its effects on the body. Learn how it is typically described and diagnosed.
