Chapter 19 - AP

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Questions and Answers

Which is true of a neuron with a resting potential?

  • The sodium pump has moved Na+ to the outside of the plasma membrane. (correct)
  • The outer surface of the plasma membrane has a negative charge.
  • The cell membrane is permeable to Na+ but impermeable to K+ ions.
  • The highest concentration of K+ is extracellular.

The first event to occur when an adequate stimulus is applied to a neuron is:

  • the sodium channels are inactivated.
  • some of the sodium channels at the point of stimulation open. (correct)
  • the potassium channels open.
  • the membrane potential moves immediately to a value of +30 mV.

Which is true of an action potential?

  • Na+ ions move extracellularly.
  • The outside of the plasma membrane is negatively charged, and the inside is positively charged. (correct)
  • The charges become equal on the outside and inside of the plasma membrane.
  • The plasma membrane is impermeable to Na+ and K+ ions.

The only ion(s) that can diffuse across a neuron's membrane when the neuron is at rest is (are):

<p>potassium. (D)</p> Signup and view all the answers

A slight shift away from the resting membrane potentials in a specific region of the plasma membrane is called a _____ potential.

<p>local (C)</p> Signup and view all the answers

During a relative refractory period:

<p>the action potential can be initiated with a strong stimulus. (C)</p> Signup and view all the answers

Within the nervous system, coding for the strength of a stimulus is accomplished through:

<p>the frequency of nerve impulses. (D)</p> Signup and view all the answers

The fastest nerve fibers in the body can conduct impulses up to approximately _____ meters per second.

<p>130 (C)</p> Signup and view all the answers

A synapse consists of:

<p>all of the above. (D)</p> Signup and view all the answers

A synaptic knob would be located on a(n):

<p>axon. (D)</p> Signup and view all the answers

When an impulse reaches a synapse:

<p>chemical transmitters are released. (A)</p> Signup and view all the answers

Excitatory neurotransmitters are most likely to:

<p>initiate an action potential. (B)</p> Signup and view all the answers

When current leaps across an insulating myelin sheath from node to node, the type of impulse conduction is called:

<p>saltatory conduction. (C)</p> Signup and view all the answers

For a neurotransmitter to produce an inhibitory postsynaptic potential, which of the following channels must open?

<p>Potassium and/or chloride channels (D)</p> Signup and view all the answers

Which of the following is true of spatial summation?

<p>Neurotransmitters released simultaneously from several presynaptic knobs converge on one postsynaptic neuron. (B)</p> Signup and view all the answers

Which of the following is not one of the main chemical classes of neurotransmitters?

<p>Triglycerides (C)</p> Signup and view all the answers

Serotonin is an example of a(n):

<p>amine neurotransmitter. (A)</p> Signup and view all the answers

The neurotransmitter(s) that inhibit(s) the conduction of pain impulses is(are):

<p>enkephalins. (B)</p> Signup and view all the answers

Neurotransmitters are released in a synapse and bind to:

<p>receptors on the postsynaptic neuron. (D)</p> Signup and view all the answers

Which of the following statements about amino acid neurotransmitters is incorrect?

<p>They are all inhibitory neurotransmitters. (B)</p> Signup and view all the answers

Severe depression can be caused by a deficit in certain brain synapses of:

<p>amines. (D)</p> Signup and view all the answers

Which of the following is not used by the body as a neurotransmitter?

<p>Peroxide (B)</p> Signup and view all the answers

Which of the following antidepressants acts by blocking the action of monoamine oxidase (MAO)?

<p>Phenelzine (D)</p> Signup and view all the answers

Compared with the outside of the neuron, the inside has a(n) _____ charge.

<p>negative (B)</p> Signup and view all the answers

Acetylcholine is in the same class of neurotransmitters as:

<p>none of the above. (D)</p> Signup and view all the answers

Dopamine, epinephrine, and norepinephrine are classified as:

<p>catecholamines. (C)</p> Signup and view all the answers

Stimulus-gated channels open in response to:

<p>sensory stimuli. (C)</p> Signup and view all the answers

The fastest nerve fibers in the body can conduct an impulse that is how much faster than the slowest fibers in the body?

<p>Almost 300 times faster (D)</p> Signup and view all the answers

Which neuron could transmit a nerve impulse the fastest?

<p>A large-diameter neuron with myelin (B)</p> Signup and view all the answers

No impulse can be sent through a neuron:

<p>during the absolute refractory period. (C)</p> Signup and view all the answers

A synapse can occur only between an axon and:

<p>any of the above. (D)</p> Signup and view all the answers

The difference between sodium and potassium in the generation of action potential is that:

<p>sodium causes depolarization of the cell membrane, and potassium causes repolarization of the cell membrane. (D)</p> Signup and view all the answers

A neurologist is using a voltmeter to measure potential. The membrane potential of a neuron was recorded at +30 mV. This is what type of membrane potential?

<p>Action (A)</p> Signup and view all the answers

Which membrane receptor acts to directly change ion permeability when stimulated?

<p>Ionotropic receptor (B)</p> Signup and view all the answers

Flashcards

Resting Potential

Neuron at rest; outer plasma membrane is positively charged; sodium pump moved Na+ to the outside.

First Event of Stimulation

Sodium channels open at the point of stimulation.

Local Potential

Shifting away from resting membrane potentials

Relative Refractory Period

Action potential can be initiated with a strong stimulus.

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Stimulus Strength Coding

Coding for the strength of a stimulus is accomplished through the frequency of nerve impulses.

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Synapse

Consists of a synaptic knob, a synaptic cleft, and the plasma membrane of a postsynaptic neuron.

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Impulse at Synapse

Releases chemical transmitters when an impulse reaches a synapse.

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Excitatory Neurotransmitters

Increase the speed of impulse conduction.

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Saltatory Conduction

Occurs when current leaps down myelinated neurons from node to node.

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Potassium/Chloride Channels

Channels that open for inhibitory post-synaptic potential.

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Spatial Summation

When neurotransmitters simultaneously are released from several presynaptic knobs converge on one postsynaptic neuron.

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Serotonin

A neurotransmitter.

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Neurotransmitters

Released in a synapse and bind to receptors on the postsynaptic neuron.

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Neuron's Charge

The inside has a negative charge.

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Acetylcholine

Same class of neurotransmitters as dopamine.

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Dopamine, Epinephrine, Norepinephrine

Classified as catecholamines.

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Stimulus-Gated Channels

Open in response to sensory stimuli.

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Large-Diameter Neuron

Transmit impulse the fastest.

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No Impulse

Cannot be sent during absolute refractive period.

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Sodium/Potassium

Depolarization and repolorization of the cell-membrane.

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Study Notes

Neuron Resting Potential

  • The cell membrane is permeable to sodium but impermeable to potassium ions
  • The sodium pump moves sodium to the outside of the plasma membrane
  • The outer surface of the plasma membrane has a negative charge

Action Potential

  • The first event after an adequate stimulus is to open some sodium channels at the point of stimulation
  • During an action potential the charges become equal on both sides of the plasma membrane
  • The plasma membrane's outside is negatively charged, and the inside is positively charged during an action potential

Ion Diffusion

  • Potassium is the only ion that can diffuse across a neuron's membrane when the neuron is at rest.

Local Potentials

  • A slight shift away from the resting membrane potentials in a specific region of the plasma membrane

Refractory Period

  • Action potential can be initiated with a strong stimulus during the relative refractory period
  • Coding for the strength of a stimulus is accomplished through the frequency of nerve impulses

Nerve Fibers

  • The fastest nerve fibers in the body can conduct impulses up to approximately 130 meters per second

Synapses

  • A synapse consists of a synaptic knob, a synaptic cleft, and the plasma membrane of a postsynaptic neuron
  • A synaptic knob would be located on an axon
  • Chemical transmitters are released when an impulse reaches a synapse
  • A synapse can occur only between an axon and a dendrite, cell body, or another axon

Synaptic Transmission

  • Excitatory neurotransmitters are most likely to initiate an action potential
  • Saltatory conduction is when current leaps across an insulating myelin sheath from node to node
  • Potassium and/or chloride channels must open for a neurotransmitter to produce an inhibitory postsynaptic potential
  • Neurotransmitters are released in a synapse and bind to receptors on the postsynaptic neuron

Summation

  • Spatial summation occurs when neurotransmitters released simultaneously from several presynaptic knobs converge on one postsynaptic neuron

Neurotransmitters

  • Triglycerides are not one of the main chemical classes of neurotransmitters
  • Serotonin is an example of an amine neurotransmitter
  • Enkephalins inhibit the conduction of pain impulses
  • An incorrect statement about amino acid neurotransmitters is that they are all inhibitory neurotransmitters
  • Glycine is a widely distributed inhibitory neurotransmitter in the spinal cord
  • Severe depression can be caused by a deficit in certain brain synapses of neuropeptides
  • Peroxide is not used by the body as a neurotransmitter
  • Phenelzine is an antidepressant that acts by blocking the action of monoamine oxidase (MAO)
  • Dopamine, epinephrine, and norepinephrine are classified as catecholamines

Membrane Potential and Impulses

  • The inside of a neuron has a negative charge compared with the outside
  • Stimulus-gated channels open in response to sensory stimuli
  • Fastest nerve fibers in the body can conduct an impulse almost 300 times faster than the slowest fibers
  • The fastest nerve impulse transmission occurs in a large-diameter neuron with myelin
  • No impulse can be sent through a neuron during the absolute refractory period

Action Potentials

  • Sodium causes depolarization of the cell membrane, and potassium causes repolarization of the cell membrane
  • A membrane potential of +30 mV indicates an action potential

Membrane Receptors

  • A gated-channel receptor acts to directly change ion permeability when stimulated

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