Neuron Ion Channel Physiology

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25 Questions

What is the ionized form trying to do?

Leave the Cytoplasm through Na Channels

Why did the ionized form block the Na Channels?

Because it couldn't leave the Cytoplasm

What happened to the Na Channels?

They were blocked

What is the location where the ionized form is trying to leave?

Cytoplasm

What type of Channels is the ionized form trying to use?

Na Channels

What is an advantage of having less bleeding during a surgical operation?

It makes the surgical field good for the surgeon

What is a drawback of high BP during a surgical operation?

It leads to more bleeding

What is an advantage of having less absorption during a surgical operation?

It results in less toxicity

What is a drawback of having more bleeding during a surgical operation?

It makes the surgical field bad for the surgeon

What is an advantage of having less toxicity during a surgical operation?

It leads to less absorption

What is the effect of adding Epinephrin to anesthetic drugs?

Vasoconstriction

What is the original effect of anesthetic drugs?

Vasodilation

What is the condition associated with the original anesthetic drugs?

Low blood pressure

What is the purpose of adding Epinephrin to anesthetic drugs?

To counteract low blood pressure

What is the result of combining anesthetic drugs with Epinephrin?

Vasoconstriction and high blood pressure

In which patients is N2O contraindicated?

Those with a pneumothorax or closed air space in the body

What is a contraindication for the use of N2O?

Tympanic membrane graft

What is a type of obstruction where N2O is contraindicated?

Closed loop bowel obstruction

What is another condition where N2O is contraindicated?

Air embolism

What is the reason for contraindicating N2O in certain patients?

Risk of expansion of closed air space

What is the pressure required for Positive Pressure Ventilation (PPV) in Laryngeal Mask Airway (LMA)?

20 cm H₂0

What is the primary objective of using Laryngeal Mask Airway (LMA)?

To provide a secure airway

What is the indication for using Laryngeal Mask Airway (LMA)?

Difficulty in bag-valve-mask ventilation

What is the advantage of using Laryngeal Mask Airway (LMA)?

Requires minimal setup and equipment

What is the contraindication for using Laryngeal Mask Airway (LMA)?

Full stomach

Study Notes

Anesthetics and Vasodilation

  • Ionized form blocked from leaving cytoplasm through Na channels, so epinephrin is added to drugs for vasoconstriction effect.

Comparison of Vasodilator and Vasoconstrictor Drugs

  • Vasodilator (Original Drugs)
    • Low blood pressure
    • More bleeding
    • Bad surgical field for surgeon
    • More absorption
    • More toxicity
  • Vasoconstrictor (Drugs with Epinephrin)
    • High blood pressure
    • Less bleeding
    • Good surgical field for surgeon
    • Less absorption
    • Less toxicity

Laryngeal Mask Airway (LMA)

  • Requires PPV >20 cm H₂O.

Contraindications of N₂O

  • Patients with pneumothorax
  • Patients with eye bubble
  • Patients with tympanic membrane graft
  • Patients with closed loop bowel obstruction
  • Patients with air embolism
  • Patients with any other closed air space in the body.

This quiz is about the ionized form's movement in cytoplasm and the role of Na channels in neuron physiology. It explores the mechanism of blocking Na channels and its implications on neuron function.

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