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Questions and Answers
What effect does pancuronium have on the body?
What is the duration of action of succinylcholine?
Which type of neuromuscular blocker is Curare?
What is the clinical use of competitive neuromuscular blockers?
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Competitive antagonism can only occur through reversible binding of the antagonist to the receptor site
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Atropine competes with acetylcholine at muscarinic receptors, decreasing the stimulatory effect of acetylcholine on gastrointestinal motility
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Hexamethonium prevents the effect of acetylcholine on nicotinic receptors in autonomic ganglia by binding to the ligand binding domain
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Irreversible competitive antagonism occurs when the antagonist forms a strong bond with the receptor that dissociates very slowly or not at all
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Functional antagonism occurs when the antagonist reduces the physiological response of the agonist by inducing the opposite response at the same receptor site
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