9 Questions
What effect does pancuronium have on the body?
Partial blockade of ganglia and adrenal medulla
What is the duration of action of succinylcholine?
5 minutes
Which type of neuromuscular blocker is Curare?
Competitive blocker
What is the clinical use of competitive neuromuscular blockers?
Facilitating surgical manipulation
Competitive antagonism can only occur through reversible binding of the antagonist to the receptor site
False
Atropine competes with acetylcholine at muscarinic receptors, decreasing the stimulatory effect of acetylcholine on gastrointestinal motility
True
Hexamethonium prevents the effect of acetylcholine on nicotinic receptors in autonomic ganglia by binding to the ligand binding domain
False
Irreversible competitive antagonism occurs when the antagonist forms a strong bond with the receptor that dissociates very slowly or not at all
True
Functional antagonism occurs when the antagonist reduces the physiological response of the agonist by inducing the opposite response at the same receptor site
False
Test your knowledge about the history and effects of Curare on the neuromuscular junction, including its early medicinal uses and chemical structure. Explore its classification and related compounds.
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