Neuromuscular Junction and Curare Quiz
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Questions and Answers

Which type of neuromuscular blocker is curare?

  • Reversal blocker
  • Depolarizing blocker
  • Fasciculating blocker
  • Competitive blocker (correct)
  • What is the effect of succinylcholine on muscle paralysis?

  • Results in cessation of respiration (apnea) (correct)
  • Leads to immediate recovery of muscles in the limbs and trunk
  • Has no effect on muscle paralysis
  • Causes rapid relaxation of intercostal muscles and diaphragm
  • What is the effect of newer agents on the central nervous system (CNS)?

  • No effect on CNS observed (correct)
  • Induces hallucinations and delusions
  • Leads to enhanced cognitive function
  • Causes significant CNS depression
  • What is the clinical use of competitive neuromuscular blockers?

    <p>Facilitation of surgical manipulation and intubation</p> Signup and view all the answers

    What is the duration of action of succinylcholine?

    <p>5 minutes</p> Signup and view all the answers

    Study Notes

    Neuromuscular Blockers

    • Curare is a depolarizing neuromuscular blocker.

    Succinylcholine

    • Succinylcholine is a depolarizing neuromuscular blocker that causes muscle paralysis by initial contraction followed by flaccid paralysis.
    • The duration of action of succinylcholine is short, typically 4-6 minutes.

    Newer Agents

    • The effect of newer agents on the central nervous system (CNS) is minimal or negligible.

    Clinical Use of Competitive Neuromuscular Blockers

    • Competitive neuromuscular blockers are used clinically to produce muscle relaxation during anesthesia, particularly for surgical procedures that require muscle relaxation.

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    Description

    Test your knowledge of the neuromuscular junction and the history of curare. Learn about the early medicinal uses of curare and its classification as a competitive neuromuscular blocker.

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