Patho 2 - Module 14
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Questions and Answers

Which neurotransmitter is primarily affected in Parkinson's Disease?

  • Norepinephrine
  • Serotonin
  • Dopamine (correct)
  • Acetylcholine
  • What is the main function of dopamine in the context of Parkinson's Disease?

  • Ensuring efficiency and grace of movement (correct)
  • Regulating sleep-wake cycles
  • Controlling appetite and satiety
  • Regulating mood and emotions
  • Which part of the brain is primarily responsible for producing dopamine in the context of Parkinson's Disease?

  • Thalamus
  • Hippocampus
  • Cerebellum
  • Basal ganglia (correct)
  • What is the classical presentation of tremors in Parkinson's Disease?

    <p>Pill rolling tremors</p> Signup and view all the answers

    What is the characteristic feature of bradykinesia in Parkinson's Disease?

    <p>Slow movement</p> Signup and view all the answers

    What type of movements are most affected by rigidity in Parkinson's Disease?

    <p>Smooth and coordinated movements</p> Signup and view all the answers

    What aggravates tremors in Parkinson's Disease?

    <p>Resting</p> Signup and view all the answers

    At what stage of movement are cogwheel movements most evident in Parkinson's Disease?

    <p>During passive range of motion</p> Signup and view all the answers

    What is the approximate percentage of dopamine loss before symptoms of Parkinson's Disease occur?

    <p>80%</p> Signup and view all the answers

    What is the most common age of incidence for Parkinson's Disease?

    <p>50</p> Signup and view all the answers

    What is the most common gender affected by Parkinson's Disease?

    <p>Both men and women equally</p> Signup and view all the answers

    What is the etiology of Parkinson's Disease?

    <p>Unknown - multifactorial</p> Signup and view all the answers

    Which neurological disorder is characterized by difficulty in walking, freezing, small shuffling steps, and stiff facial features?

    <p>Parkinson's disease</p> Signup and view all the answers

    What is the goal of treatment for Parkinson's disease?

    <p>To restore neurotransmitter balance, reduce rigidity, and improve mobility</p> Signup and view all the answers

    Which disorder is associated with family history, multiple sclerosis, and degeneration of myelin sheath?

    <p>Young-Onset Parkinson's Disease</p> Signup and view all the answers

    What is the characteristic symptom of Multiple Sclerosis?

    <p>Paresthesias</p> Signup and view all the answers

    How is the diagnosis of Multiple Sclerosis typically made?

    <p>Based on history, physical examination, and MRI</p> Signup and view all the answers

    What is the cause of loss of motor function in ALS (Lou Gehrig's Disease)?

    <p>Damaged motor neurons</p> Signup and view all the answers

    Which therapy aims to control excessive oxidative stress in ALS patients?

    <p>Radicava</p> Signup and view all the answers

    What is the characteristic complication of Huntington's Disease?

    <p>Dementia</p> Signup and view all the answers

    What is the main characteristic of Parkinson's Disease?

    <p>Dopamine deficiency</p> Signup and view all the answers

    Which disorder is associated with impaired mobility, risk for aspiration, and autonomic nervous system issues?

    <p>Parkinson's disease</p> Signup and view all the answers

    What is the primary cause of symptoms in Multiple Sclerosis?

    <p>Destruction of the myelin sheath in the central nervous system</p> Signup and view all the answers

    Which treatment aims to preserve nerve function and reduce flare-ups in ALS (Lou Gehrig's Disease)?

    <p>Immunosuppression therapy</p> Signup and view all the answers

    Study Notes

    Neurological Disorders Overview

    • Bradykinesia: difficulty in walking, freezing, small shuffling steps, impaired mobility, stiff facial features, rigidity, and risk for aspiration
    • Parkinson's disease: diagnosed based on history, physical examination, and response to dopamine replacement, with symptoms including autonomic nervous system issues, orthostatic hypotension, constipation, urine retention, speech impairment, and cognitive dysfunction
    • Treatment for Parkinson's: goal to restore neurotransmitter balance, reduce rigidity, and improve mobility through medications, deep brain stimulation, and levodopa-carbidopa gel infusion
    • Young-Onset Parkinson's Disease: associated with family history, multiple sclerosis, and degeneration of myelin sheath
    • Multiple Sclerosis: autoimmune disease affecting the central nervous system, causing myelin breakdown, and leading to symptoms such as paresthesias, visual impairments, and motor weakness
    • Diagnosis of Multiple Sclerosis: based on history, physical examination, and diagnostic tests including MRI, visual evoked potential, and spinal tap
    • ALS (Lou Gehrig's Disease): results in loss of motor function due to damaged motor neurons, leading to muscle weakness, atrophy, and respiratory failure
    • ALS Treatment: aims to preserve nerve function and reduce flare-ups through immunosuppression therapy
    • Radicava: drug therapy used to control excessive oxidative stress in ALS patients
    • Huntington's Disease: autosomal dominant disorder causing degeneration of basal ganglia, leading to random jerky movements, dementia, and complications such as pneumonia and falls
    • Multiple Sclerosis: an autoimmune disease causing destruction of the myelin sheath in the central nervous system, leading to disturbances in nerve transmission
    • Parkinson's Disease: characterized by dopamine deficiency, leading to muscle rigidity, bradykinesia, and resting tremors

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    Description

    Test your knowledge of neurological disorders with this overview quiz. Learn about the symptoms, diagnosis, and treatment of Parkinson's disease, multiple sclerosis, ALS (Lou Gehrig's Disease), and Huntington's disease. Explore the impact of these conditions on the central nervous system and the strategies used to manage them.

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