Neurogenic Inflammation in Tendon Pathology

Which of the following is the primary function of long and thin tendons?

How does the cross-sectional area of a tendon affect the internal stress experienced by the tendon?

Which of the following is the primary source of nutrition for mature tendons?

Which part of the Tibialis Anterior tendon has an avascular zone?

Which tendon has a richer intrinsic vascularity that may enhance its use as a graft?

What is the primary cause of the transition to the symptomatic phase of tendinopathy according to the text?

What is the key factor that determines whether the tendon can fully heal according to the 'iceberg theory' of tendinopathy?

What is the primary reason for the slow healing process in tendinopathy according to the 'failed healing theory'?

What is the key difference between the 'under-stimulation' and 'over-stimulation' hypotheses for the pathogenesis of tendinopathy?

How does tendinopathy affect the mechanical function of the tendon according to the text?

What is the primary cause of tendon tissue denaturation according to the passage?

According to the continuum model of tendon pathology, which stage is characterized by failed tendon healing?

Which of the following is NOT a key factor in the pathogenesis of tendinopathy according to the passage?

What is the relationship between inflammation and tissue degeneration in the pathogenic cascade of tendinopathy, according to the passage?

Why is crimp morphology in tendon tissue important?

What is the function of tenocyte cell contractility in tendon healing and regeneration?

How do tendon collagen fibres behave during elongation (load)?

What characterizes normal tendon microstructure?

What is a proposed implication of crimp formation requiring forces generated by cells and being sensitive to the relative mechanical properties of fibrils and inter-fibrillar material?

What happens to the crimp angle in tendons as we age?

What is a proposed explanation for the changing crimp morphology with age?

Which fibers in a tendon receive differentially greater load during deformation, and why?

What is a proposed mechanism for the difference between tissue and fibril strain in tendons?

What is a potential consequence of failure to control exercise-induced hyperthermia in tendons?

Which of the following is a characteristic of the asymptomatic phase of tendinopathy?

Which of the following statements about the symptomatic phase of tendinopathy is true?

Which of the following is a function of inflammatory cytokines in the context of tendinopathy?

What is the role of matrix metalloproteinases in the pathogenesis of tendinopathy?

How does glycated lysine contribute to the structure of collagen fibers?

What is the main role of sugar-mediated AGEs in collagen crosslinking?

In tendon insertion, what is the function of the tendon-like finger projections into muscle tissue?

What happens at the muscle-tendon junction regarding collagenous fibrils and sarcolemma?

How do shear forces affect the interfaces at the muscle-tendon junction?

Which type of cross-linkages are associated with abnormal conditions like diabetes?

What effect does increased glycated lysine have on collagen fibers?

How do Advanced Glycation End products (AGEs) impact tissue mechanical properties?

What is the role of tendon crimp formation in mechanical function restoration?

How does collagen crosslinking affect tissue healing and regeneration?