Neurodegenerative Diseases Overview

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Questions and Answers

What is a common feature of neurodegenerative diseases?

  • Lack of any immune system involvement
  • Activation of the innate immune system (correct)
  • Suppression of the immune system
  • Activation of the adaptive immune system

Which of the following is NOT a type of dementia mentioned in the passage?

  • Alzheimer's Disease
  • Huntington's Disease
  • Vascular Dementia (correct)
  • Frontotemporal Lobar Degeneration

What is the most common cause of dementia in the elderly according to the passage?

  • Alzheimer's Disease (correct)
  • Frontotemporal Lobar Degeneration
  • Parkinson's disease
  • Amyotrophic Lateral Sclerosis

What is a characteristic feature of the neurofibrillary tangles in Alzheimer's Disease?

<p>They are found in the cytoplasm of neurons (D)</p> Signup and view all the answers

What is the appearance of neurofibrillary tangles in tissue sections according to the passage?

<p>They appear as ghost-like or tombstone-like structures (C)</p> Signup and view all the answers

Which of the following statements about the diagnosis of Alzheimer's Disease is correct according to the passage?

<p>Diagnosis is made by a combination of clinical, radiological and pathological methods (B)</p> Signup and view all the answers

Which neurodegenerative disease is characterized by progressive neuron loss affecting the basal ganglia?

<p>Parkinson's Disease (A)</p> Signup and view all the answers

What is the histological marker of Huntington's Disease?

<p>Protein communities appear in inclusions (C)</p> Signup and view all the answers

Which neurodegenerative disease is associated with cognitive changes, memory, behavior, and language disorders?

<p>Alzheimer's Disease (B)</p> Signup and view all the answers

What is a common feature of neurodegenerative diseases in terms of neuronal loss?

<p>Neuronal loss is selective (D)</p> Signup and view all the answers

Which protein is directly toxic to neurons due to its aberrant localization in neurodegenerative diseases?

<p>α-synuclein (D)</p> Signup and view all the answers

Which neurodegenerative disease primarily affects motor neurons resulting in weakness, difficulty in swallowing, and breathing?

<p>Amyotrophic Lateral Sclerosis (D)</p> Signup and view all the answers

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