Neurodegenerative Diseases Overview

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12 Questions

What is a common feature of neurodegenerative diseases?

Activation of the innate immune system

Which of the following is NOT a type of dementia mentioned in the passage?

Vascular Dementia

What is the most common cause of dementia in the elderly according to the passage?

Alzheimer's Disease

What is a characteristic feature of the neurofibrillary tangles in Alzheimer's Disease?

They are found in the cytoplasm of neurons

What is the appearance of neurofibrillary tangles in tissue sections according to the passage?

They appear as ghost-like or tombstone-like structures

Which of the following statements about the diagnosis of Alzheimer's Disease is correct according to the passage?

Diagnosis is made by a combination of clinical, radiological and pathological methods

Which neurodegenerative disease is characterized by progressive neuron loss affecting the basal ganglia?

Parkinson's Disease

What is the histological marker of Huntington's Disease?

Protein communities appear in inclusions

Which neurodegenerative disease is associated with cognitive changes, memory, behavior, and language disorders?

Alzheimer's Disease

What is a common feature of neurodegenerative diseases in terms of neuronal loss?

Neuronal loss is selective

Which protein is directly toxic to neurons due to its aberrant localization in neurodegenerative diseases?

α-synuclein

Which neurodegenerative disease primarily affects motor neurons resulting in weakness, difficulty in swallowing, and breathing?

Amyotrophic Lateral Sclerosis

Learn about neurodegenerative diseases such as Alzheimer’s Disease, Frontotemporal Lobar Degenerations, Parkinson’s Disease, Multiple System Atrophy, Huntington's Disease, and Spinocerebellar Degenerations. Understand how these diseases affect primary gray matter through progressive neuron loss and selective neuronal loss.

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