Neuroanatomy Chapters 13 and 16

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Questions and Answers

What primary function does the parasympathetic nervous system (PNS) have on the heart?

  • Accelerates heart rate
  • Inhibits heart muscle contraction
  • Increases blood pressure
  • Lowers heart rate (correct)

During a moment of crisis, which system predominantly stimulates the body?

  • Sympathetic nervous system (correct)
  • Somatic nervous system
  • Enteric nervous system
  • Parasympathetic nervous system

What neurotransmitter is primarily associated with the adrenergic system?

  • Norepinephrine (correct)
  • Dopamine
  • Acetylcholine
  • Serotonin

Which enzyme converts histidine into histamine?

<p>Histidine Hydroxylase (B)</p> Signup and view all the answers

What is one of the primary roles of the serotonergic system?

<p>Gastrointestinal motility (A)</p> Signup and view all the answers

What is the final product of the epinephrine pathway?

<p>Epinephrine (D)</p> Signup and view all the answers

In which area does acetaminophen primarily exert its effects?

<p>Brain and spinal cord (B)</p> Signup and view all the answers

Which neurotransmitter pathway does not involve cAMP as a primary mechanism?

<p>Acetylcholine (B)</p> Signup and view all the answers

What type of neurons are contained in the Dorsal Root of the spinal column?

<p>Sensory neurons (C)</p> Signup and view all the answers

Which structure is responsible for carrying motor signals down the spinal cord?

<p>Anterior Root (C)</p> Signup and view all the answers

Which statement describes the post-ganglionic neurons of the sympathetic nervous system?

<p>They are long and non-myelinated. (B)</p> Signup and view all the answers

What type of receptors do post-ganglionic neurons in the parasympathetic nervous system target?

<p>Cholinergic muscarinic receptors (B)</p> Signup and view all the answers

What is the primary neurotransmitter released by the adrenal medulla in the sympathetic nervous system?

<p>Epinephrine (B)</p> Signup and view all the answers

Which of the following accurately describes the origin of the sympathetic nervous system?

<p>Thoracolumbar region T1-L2 (A)</p> Signup and view all the answers

What characterizes the autonomic tone of autonomic motor neurons?

<p>Maintains a resting level of activity. (D)</p> Signup and view all the answers

Which types of receptors are always excitatory when activated by acetylcholine?

<p>Nicotinic receptors (D)</p> Signup and view all the answers

Flashcards

What does the dorsal root carry?

The dorsal root of the spinal cord carries sensory neurons, which transmit information from the body to the central nervous system (CNS).

What does the ventral root carry?

The ventral root of the spinal cord carries motor neurons, which transmit signals from the CNS to muscles and glands.

What do motor neurons do?

Motor neurons are responsible for sending signals from the central nervous system to muscles and glands, causing them to contract or secrete.

What do sensory neurons do?

Sensory neurons are responsible for transmitting information from sensory receptors (like skin, eyes, ears) to the central nervous system.

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What is a reflex arc?

A reflex arc is a neural pathway that allows for a rapid response to a stimulus without conscious thought. It involves a sensory receptor, sensory neuron, interneuron, motor neuron, and effector.

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What is the sympathetic nervous system responsible for?

The sympathetic nervous system is responsible for the 'fight or flight' response, increasing heart rate, dilating pupils, and preparing the body for stress.

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What is the parasympathetic nervous system responsible for?

The parasympathetic nervous system is responsible for the 'rest and digest' response, slowing down heart rate, constricting pupils, and promoting digestion.

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What is autonomic tone?

Autonomic tone refers to the constant, low-level activity of the autonomic nervous system that helps maintain homeostasis in the body.

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Autonomic Plexuses

Nerve networks found in the thoracic and abdominopelvic cavities, composed of sympathetic post-ganglionic and parasympathetic pre-ganglionic fibers. They travel alongside blood and lymphatic vessels to supply visceral organs.

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Autonomic Tone

The balance between sympathetic and parasympathetic nervous system activity at a given moment.

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Dual Innervation

State where a single organ is innervated by both sympathetic and parasympathetic systems, promoting simultaneous but often opposing effects.

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Sympathetic Nervous System (SNS)

The nervous system branch responsible for "fight-or-flight" responses, releasing norepinephrine (NE) and epinephrine (E)

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Parasympathetic Nervous System (PNS)

The nervous system branch responsible for "rest-and-digest" responses, releasing acetylcholine (ACh)

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Norepinephrine (NE)

A type of neurotransmitter that primarily acts on adrenergic receptors in the sympathetic nervous system. Also known as noradrenaline.

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Epinephrine Pathway

The pathway that produces epinephrine, the primary hormone released by the adrenal glands during stress

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Dopamine Pathway

The pathway that produces dopamine, a neurotransmitter involved in movement, motivation, and reward. Found in parts of the brain like the substantia nigra.

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Study Notes

Chapter 13: Spinal Column Structure

  • The posterior root is the dorsal root, containing sensory neurons.
  • The spinal (dorsal) root ganglion also holds sensory neurons.
  • The anterior root is the ventral root, housing motor neurons.
  • Motor neurons send signals from the CNS, traveling down the spinal cord.
  • Sensory neurons carry signals to the CNS, traveling upwards towards the brain.
  • A reflex arc involves a sensory receptor, sensory neuron, CNS processing, motor neuron, and effector.

Chapter 16: PNS and SNS

  • The sympathetic system originates in the thoracolumbar region (T1-L2).
  • Sympathetic preganglionic fibers are short and myelinated.
  • Sympathetic postganglionic fibers are long and unmyelinated.
  • Sympathetic postganglionic fibers are adrenergic.
  • The parasympathetic system originates in craniosacral regions.
  • Parasympathetic preganglionic fibers are long and myelinated.
  • Parasympathetic postganglionic fibers are short and unmyelinated.
  • Parasympathetic postganglionic fibers are cholinergic.
  • Sympathetic systems generally increase or dilate, whereas para-sympathetic systems generally decrease or constrict.
  • The "MANTRA" for synaptic transmitters: cholinergic neurotransmitter (acetylcholine) is released by all preganglionic neurons in both systems, and by postganglionic neurons in parasympathetic. Adrenergic neurotransmitters (norepinephrine and epinephrine) are used by postganglionic sympathetic neurons.

Dual Innervation

  • Autonomic plexuses are nerve networks in the thoracic and abdominal cavities, formed by sympathetic and parasympathetic fibers.
  • The heart receives dual innervation.
  • Acetylcholine (ACh) slows heart rate while norepinephrine (NE) speeds it up.
  • Parasympathetic dominates during rest, but sympathetic takes over in times of stress.

Autonomic Pathways

  • Parasympathetic pathways involve ganglia near target organs.
  • Cholinergic pathways use ACh at all synapses.
  • Sympathetic pathways use ganglia near the spinal cord.
  • Norepinephrine is released at the target organ.

Postganglionic Autonomic Neurotransmitters

  • Sympathetic division uses norepinephrine (NE), with alpha and beta adrenergic receptors.
  • Parasympathetic division uses acetylcholine (ACh), with muscarinic and nicotinic cholinergic receptors.
  • Acetylcholinesterase inactivates ACh; MAO inactivates NE.

Adrenergic, Dopaminergic, and Serotonergic Synapses

  • Diagrams illustrate neurotransmitter synthesis, release, reuptake, and inactivation in these pathways.
  • Various drugs influence these pathways, with specific target receptors and effects.

Agonists and Antagonists of Neurotransmitter Receptors

  • Cholinergic receptors have muscarinic and nicotinic types,
  • Adrenergic receptors have alpha and beta subtypes.
  • Agonists and antagonists bind to receptors, affecting the neurotransmitter's action.

Properties of Adrenergic Receptors

  • Different adrenergic receptors (α1, α2, β1, β2, β3) have distinct locations and responses to norepinephrine and epinephrine.

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