Nervous System Overview

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Questions and Answers

Which part of the brain is responsible for regulating visceral functions?

  • Thalamus
  • Autonomic Nervous System (correct)
  • Hippocampus
  • Cerebellum

What is the main function of unipolar neurons?

  • Transmit sensory information (correct)
  • Motor impulse transmission
  • Facilitate muscle contraction
  • Connect different parts of the nervous system

Which division of the autonomic nervous system is primarily responsible for the 'fight or flight' response?

  • Central Nervous System
  • Cerebral division
  • Parasympathetic division
  • Sympathetic division (correct)

Which structure is part of the rhombencephalon?

<p>Cerebellum (D)</p> Signup and view all the answers

What is the structural and functional unit of the nervous system?

<p>Neuron (A)</p> Signup and view all the answers

Which of the following is a characteristic of multipolar neurons?

<p>Have many poles with one axon (C)</p> Signup and view all the answers

What part of the forebrain is involved in the processing of sensory information?

<p>Cerebral hemispheres (D)</p> Signup and view all the answers

Which nervous system division is concerned with skeletal muscle activity?

<p>Somatic Nervous System (D)</p> Signup and view all the answers

What is the function of the myelin sheath in nerve fibers?

<p>Facilitates faster conduction of nerve impulses (C)</p> Signup and view all the answers

Which cells are responsible for the formation of the myelin sheath in peripheral nerves?

<p>Schwann cells (B)</p> Signup and view all the answers

What is the role of neurotrophins?

<p>To support the growth and functioning of nervous tissue (B)</p> Signup and view all the answers

Which structure facilitates 'saltatory conduction' in axons?

<p>Nodes of Ranvier (D)</p> Signup and view all the answers

What is the primary function of sensory or afferent neurons?

<p>To carry sensory impulses from the periphery to the central nervous system (D)</p> Signup and view all the answers

Which type of neuron is characterized by a long axon and a cell body located in different parts of the central nervous system?

<p>Golgi Type I Neuron (D)</p> Signup and view all the answers

Which type of flow transports proteins from the soma to the axon?

<p>Axonal flow (D)</p> Signup and view all the answers

What is the primary role of Nissl bodies in neurons?

<p>To synthesize proteins (D)</p> Signup and view all the answers

At which developmental stage is the myelin sheath of the peripheral nerve formed?

<p>Begins at the 4th month of intrauterine life (C)</p> Signup and view all the answers

Which structure is not found in the axon of a neuron?

<p>Nissl granules (C)</p> Signup and view all the answers

What is the primary component of the axon's structure?

<p>Axoplasm (C)</p> Signup and view all the answers

What is the approximate length of the longest axon in a neuron?

<p>1 meter (C)</p> Signup and view all the answers

What type of membrane surrounds the axon?

<p>Neurilemmal membrane (C)</p> Signup and view all the answers

What is the function of the epineurium in nerve coverings?

<p>To cover the entire nerve (D)</p> Signup and view all the answers

Which part of the neuron is responsible for transmitting impulses toward the nerve cell body?

<p>Dendrite (D)</p> Signup and view all the answers

What is a defining characteristic of Golgi Type II neurons?

<p>They have short axons (D)</p> Signup and view all the answers

What is the primary characteristic of first-degree nerve fiber injury?

<p>Only demyelination occurs (D)</p> Signup and view all the answers

Which degree of nerve injury is characterized by the interruption of the endoneurium while the epineurium and perineurium remain intact?

<p>Third Degree (D)</p> Signup and view all the answers

Wallerian degeneration typically occurs in which degree of nerve injury?

<p>Second Degree (D)</p> Signup and view all the answers

What is NOT a requirement for successful regeneration of a nerve fiber?

<p>The nerve must be surgically repaired (D)</p> Signup and view all the answers

During which stage of regeneration does the myelination of a new axon occur?

<p>Stage 3 (D)</p> Signup and view all the answers

What is the primary function of beta-subunits in nerve growth factor?

<p>Stimulating nerve growth (C)</p> Signup and view all the answers

Which neurotrophic factor is known to protect motor neurons and is used in treating motor neuron diseases?

<p>Glial cell line-derived neurotrophic factor (GDNF) (B)</p> Signup and view all the answers

What characteristic distinguishes myelinated nerve fibers from non-myelinated nerve fibers?

<p>Myelinated fibers conduct impulses faster (B)</p> Signup and view all the answers

What type of nerve fibers arise from the spinal cord?

<p>Spinal Nerve Fibers (A)</p> Signup and view all the answers

Neurotrophin-3 (NT-3) is primarily involved in which function?

<p>Regulating neurotransmitter release (D)</p> Signup and view all the answers

Which factor is known to protect dopaminergic neurons?

<p>Glial cell line-derived neurotrophic factor (GDNF) (B)</p> Signup and view all the answers

Which type of nerve fibers supply skeletal muscles?

<p>Somatic Nerve Fibers (D)</p> Signup and view all the answers

BDGF is primarily found in which of the following tissues?

<p>Pig brains and human brain (D)</p> Signup and view all the answers

Which type of nerve fibers secrete noradrenaline?

<p>Adrenergic Nerve Fibers (D)</p> Signup and view all the answers

What is the characteristic of Type C nerve fibers?

<p>They are the thinnest nerve fibers. (A)</p> Signup and view all the answers

What occurs during the absolute refractory period?

<p>The nerve does not respond to any stimulus. (A)</p> Signup and view all the answers

Which term describes the form of conduction where impulses jump from one node to another?

<p>Saltatory Conduction (B)</p> Signup and view all the answers

What is the effect of continuous depolarization on nerve fibers?

<p>Decreases excitability over time. (D)</p> Signup and view all the answers

Which statement best describes excitability in nerve fibers?

<p>It is a physiochemical change in response to a stimulus. (D)</p> Signup and view all the answers

What happens when multiple subliminal stimuli are combined in a short time?

<p>Summation occurs. (B)</p> Signup and view all the answers

Which of the following describes the all-or-none law of nerve stimulation?

<p>A nerve either responds at maximum capacity or not at all. (A)</p> Signup and view all the answers

Flashcards

Cerebral Hemispheres

The largest part of the brain, responsible for higher cognitive functions like thinking, memory, and language.

Basal Ganglia

A group of structures deep within the brain involved in planning, movement, and coordination.

Hippocampus

A structure in the brain involved in forming new memories.

Thalamus

The central relay station for sensory information.

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Hypothalamus

A structure responsible for regulating body temperature, hunger, thirst, and sleep.

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Central Nervous System (CNS)

Part of the nervous system made of the brain and spinal cord.

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Peripheral Nervous System (PNS)

Part of the nervous system that connects the CNS to the rest of the body.

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Somatic Nervous System

The subdivision of the PNS responsible for voluntary control of skeletal muscles.

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What do sensory neurons do?

Sensory neurons carry sensory impulses from the periphery to the central nervous system (CNS). They act like messengers, bringing information about your senses, like touch, taste, and smell, to the brain and spinal cord.

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Golgi Type I neurons:

Golgi Type I neurons have long axons that can reach remote peripheral organs. Imagine them as long-distance runners, connecting different parts of the nervous system.

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Golgi Type II neurons:

Golgi Type II neurons have short axons that stay within the cerebral cortex or spinal cord. Think of them as local messengers, communicating within a specific area.

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What is the nerve cell body?

The nerve cell body, or soma, is the control center of a neuron. It contains the nucleus and other important components for the neuron's function.

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What are Nissl bodies?

Nissl bodies are small granules found in the cytoplasm of neurons. They synthesize proteins, which are essential for the neuron's function.

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What do dendrites do?

Dendrites are branched processes of a neuron that transmit impulses towards the nerve cell body. Think of them as receivers, gathering information from other neurons.

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What does the axon do?

The axon is a long, thin process of a neuron that transmits impulses away from the nerve cell body. Think of it as a transmitter, sending information to other neurons or muscle cells.

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What is the epineurium?

The epineurium is a membrane that covers the entire nerve. It provides protection and support for the nerve fibers.

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Third Degree Nerve Injury (Neurotmesis)

A type of nerve injury where the endoneurium is interrupted, but the epineurium and perineurium remain intact. Recovery is slow.

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Wallerian Degeneration

The process of degeneration that occurs in the axon of a nerve fiber distal to the injury site.

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Retrograde Degeneration

A process that occurs in the neuron cell body after an injury to its axon, leading to changes in the cell body.

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Fifth Degree Nerve Injury

A type of nerve injury where all coverings of the nerve are interrupted, leading to complete nerve damage.

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Axon Regeneration

A process of nerve regeneration where a new axon grows from the cell body to the site of injury.

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Axoplasm

The cytoplasm within the axon, containing structures like mitochondria, neurofibrils, and axoplasmic vesicles.

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Axolemma

The membrane covering the axon, responsible for regulating what enters and exits the axon.

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Axonal Flow

The process by which proteins synthesized in the cell body are transported along the axon.

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Myelin Sheath

The fatty sheath covering the axon, responsible for faster conduction of nerve impulses.

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Nodes of Ranvier

Gaps in the myelin sheath where the axolemma is exposed, allowing for saltatory conduction.

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Internode

The segment of the axon between two Nodes of Ranvier, covered by myelin.

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Myelinogenesis

The process of forming the myelin sheath by Schwann cells, starting in the 4th month of fetal development.

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Neurilemma

A thin membrane surrounding the axon, containing Schwann cells with flattened nuclei, and essential for myelin sheath formation.

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Nerve Growth Factor (NGF)

A protein that promotes the growth and survival of neurons, particularly in sympathetic and sensory neurons.

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Beta-subunits of NGF

One of the subunits of NGF, responsible for its ability to stimulate nerve growth.

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Brain-Derived Neurotrophic Factor (BDNF)

A protein found in the brain and sperm that promotes the survival of sensory and motor neurons.

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Ciliary Neurotrophic Factor (CNTF)

A protein secreted by peripheral nerves, ocular muscles, and cardiac muscle that protects neurons in specific regions.

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Glial Cell Line-Derived Neurotrophic Factor (GDNF)

A protein found in neuroglial cells that protects dopaminergic neurons, critical for movement control.

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Fibroblast Growth Factor (FGF)

A protein originally discovered for its role in promoting the growth of fibroblasts, but also known to protect neurons.

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Neurotrophin-3 (NT-3)

A protein that acts on various neurons, including motor neurons, and regulates neurotransmitter release.

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Classification of Nerve Fibers

A classification of nerve fibers based on their structural features, distribution, origin, and function.

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Cholinergic Nerve Fibers

Nerve fibers that release acetylcholine (ACh) as their neurotransmitter. They play a crucial role in various functions, including muscle contraction, heart rate regulation, and cognitive processes.

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Adrenergic Nerve Fibers

Nerve fibers that release noradrenaline (norepinephrine) as their neurotransmitter. They are involved in regulating various physiological processes, such as heart rate, blood pressure, and stress response.

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Type A Nerve Fibers

The thickest type of nerve fiber, classified into subtypes based on their speed and function. These fibers are responsible for transmitting rapid and precise signals, including those involved in muscle contraction and sensory perception.

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Type B Nerve Fibers

Thinner than Type A fibers, these myelinated nerve fibers transmit signals at a moderate speed. They are involved in various functions, including sensory perception, pain transmission, and autonomic regulation.

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Type C Nerve Fibers

The thinnest and unmyelinated nerve fibers, transmitting signals at the slowest speed. They are responsible for carrying pain sensations, temperature signals, and autonomic functions.

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Excitability

The ability of a nerve fiber to respond to a stimulus by generating an action potential. It is a fundamental property of nerve cells, allowing them to communicate with each other and the rest of the body.

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Action Potential

The rapid depolarization and repolarization of a nerve fiber membrane, creating a brief electrical signal that travels along the nerve. It is the primary way nerve cells communicate with each other and the rest of the body.

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Refractory Period

The period after an action potential during which the nerve cell is less likely to generate another action potential. This limits the rate of nerve impulse transmission.

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Study Notes

Nervous System Overview

  • The nervous system is divided into two main sections: central and peripheral.
  • The central nervous system consists of the brain and spinal cord.
  • The peripheral nervous system consists of nerves branching out from the brain and spinal cord.

Parts of the Brain

  • Prosencephalon (Forebrain): Divided into telencephalon and diencephalon.
    • Telencephalon: Cerebral hemispheres, basal ganglia, hippocampus, amygdala.
    • Diencephalon: Thalamus, hypothalamus, metathalamus, subthalamus.
  • Mesencephalon (Midbrain): Also known as the midbrain.
  • Rhombencephalon (Hindbrain): Divided into metencephalon and myelencephalon.
    • Metencephalon: Pons and cerebellum.
    • Myelencephalon: Medulla oblongata.

Peripheral Nervous System (PNS)

  • The peripheral nervous system (PNS) is made up of neurons and their processes throughout the body.
  • Cranial nerves arise from the brain.
  • Spinal nerves arise from the spinal cord.
  • It is divided into two subdivisions:
    • Somatic nervous system: Controls voluntary muscle movements.
    • Autonomic nervous system: Regulates involuntary functions (e.g., heart rate, digestion).

Neuron Structure

  • Neurons consist of a cell body, dendrites, and an axon.
  • Dendrites receive signals.
  • Axons transmit signals.

Neuron Classification

  • Classified by number of poles:
    • Unipolar: Single pole.
    • Bipolar: Two poles.
    • Multipolar: Multiple poles.
  • Classified by function:
    • Motor (efferent): Carry impulses from CNS to muscles/glands.
    • Sensory (afferent): Carry impulses from sensory receptors to CNS.
  • Classified by length of axon:
    • Golgi type I: Long axons.
    • Golgi type II: Short axons.

Neuron Structure Continued

  • Nerve cell bodies contain Nissl bodies (granules), neurofibrils, nucleus, etc.
  • Nissl bodies are associated with protein synthesis.
  • Myelin sheath surrounds some nerve fibers and helps speed up transmission.

Myelin Sheath Detail

  • Myelin sheath, is responsible for faster conduction of the nerve impulse.
  • Saltatory conduction: The way an impulse jumps from one node of Ranvier to the next.
  • Neurilemma is the outer layer of the myelin.

Functions of Myelin Sheath

  • Faster conduction of impulses.
  • Insulating capacity, preventing stimulation of adjacent nerve fibres.

Neurotrophic factors

  • These proteins play a vital role in the growth, survival and functioning of the neurons.
  • Nerve growth factor (NGF) is a key neurotrophin.

Nerve Fiber Properties

  • Excitability: Ability of a neuron to respond to a stimulus.
  • Conductivity: Ability of a neuron to transmit an impulse.
  • Refractory Period: Period of time immediately after a nerve impulse when the neuron cannot respond to another stimulus.
  • Summation: Adding together multiple subthreshold stimuli to reach a threshold for firing.
  • Adaptation: Decreased responsiveness to a sustained stimulus.
  • All-or-None Law: A nerve fiber will fire at maximum strength or not at all.

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