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Questions and Answers
What is the electrical potential of a resting nerve cell?
What is the electrical potential of a resting nerve cell?
-70mV
Which of the following is NOT a reason why the inside of a resting nerve cell has a negative electrical charge?
Which of the following is NOT a reason why the inside of a resting nerve cell has a negative electrical charge?
What is the name of the protein embedded in the cell membrane that helps maintain the resting membrane potential?
What is the name of the protein embedded in the cell membrane that helps maintain the resting membrane potential?
Sodium-Potassium pump
Ion channels are ion-specific.
Ion channels are ion-specific.
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Which type of ion channel is always open?
Which type of ion channel is always open?
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What is the function of a gated ion channel?
What is the function of a gated ion channel?
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What type of gated ion channel is responsible for the rapid depolarization of the cell membrane during an action potential?
What type of gated ion channel is responsible for the rapid depolarization of the cell membrane during an action potential?
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At rest, sodium channels are open.
At rest, sodium channels are open.
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Potassium channels are always open.
Potassium channels are always open.
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How does the movement of potassium through ungated channels contribute to the resting membrane potential?
How does the movement of potassium through ungated channels contribute to the resting membrane potential?
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Study Notes
Nervous System Lecture 2: Electrical Properties of a Resting Nerve Cell
- Nerve cells communicate electrically. The electrical signal travels from the cell body down the axon. Chemical communication also occurs, but this lecture focuses on the electrical properties.
- A resting nerve cell's interior is more negatively charged than its exterior. This difference is measured in millivolts (mV) and typically is -70mV.
- The inside of the cell is more negative, while the outside is more positive.
- Three reasons for the negative electrical charge of a resting nerve cell include
- A higher concentration of negatively charged proteins inside the cell
- The sodium-potassium pump
- The behavior of ion channels
Sodium-Potassium Pump
- The sodium-potassium pump actively moves sodium ions (Na+) out of the cell and potassium ions (K+) into the cell. This process is critical in maintaining the cell's negative resting potential.
- This pump requires energy in the form of ATP to function.
- The pump actively moves 3 sodium ions out of the cell and 2 potassium ions into the cell; this creates an electrochemical gradient (difference in concentration on either side of the membrane).
Behavior of ion channels
- Ion channels are proteins that allow ions to pass through the cell membrane.
- Channels can be either gated or ungated. Ungated channels are always open. Gated channels can open and close.
- Several types of gated channels exist:
- Voltage-gated channels: Open or close in response to changes in the membrane potential
- Ligand-gated channels: Open or close in response to a specific chemical signal (ligand)
- Mechanically-gated channels: Open or close in response to mechanical pressure or stretching
- Ions move from areas of high concentration to low concentration.
- At rest, sodium channels are mostly closed, allowing little sodium to cross the membrane; gated potassium channels usually allow some passive movement of potassium to maintain resting potential.
- Ungated potassium channels allow potassium ions to leak out of the cell, contributing to the negative charge inside the cell.
- Sodium channels are predominantly closed, keeping sodium ions outside of the cell.
Nerve Cell Activation
- When the nerve cell is activated, the membrane potential changes. This results in a rapid reversal of the electrical charge across the cell membrane.
- This change in charge allows an electrochemical signal to travel along the axon.
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Description
Explore the electrical properties of a resting nerve cell in this lecture quiz. Learn about the mechanisms behind the negative charge of the cell and the crucial role of the sodium-potassium pump. Test your understanding of nerve cell communication.