Neoplasia Goldsmith Objectives
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Questions and Answers

What is the primary difference between benign and malignant tumors?

  • Benign tumors are composed of differentiated cells, while malignant tumors are composed of undifferentiated cells
  • Benign tumors are unable to metastasize, while malignant tumors can metastasize
  • Benign tumors are slow-growing, while malignant tumors are rapidly dividing
  • All of the above (correct)

Which of the following is NOT a characteristic of cancer cells?

  • Increased cell-cell adhesion (correct)
  • Production of degradative enzymes
  • Loss of contact inhibition
  • Expression of altered tissue antigens

What is the role of proto-oncogenes in oncogenesis?

  • They encode growth factors or second messengers that stimulate cell growth (correct)
  • They inhibit cell growth and differentiation
  • They facilitate DNA repair
  • They promote apoptosis

Which of the following is NOT a step in the cancer cell transformation process by chemicals?

<p>Regression (D)</p> Signup and view all the answers

What is the primary function of tumor suppressor genes (anti-oncogenes)?

<p>Inhibit cell growth and differentiation (D)</p> Signup and view all the answers

Which of the following is NOT a risk factor for cancer development?

<p>Regular exercise (C)</p> Signup and view all the answers

What is the primary cause of cancer cachexia?

<p>Protein wasting (C)</p> Signup and view all the answers

Which of the following is NOT a common treatment modality for cancer?

<p>Gene therapy (B)</p> Signup and view all the answers

What is the primary goal of targeted cancer therapy?

<p>To target specific molecular pathways or mutations in cancer cells (D)</p> Signup and view all the answers

What is the primary mechanism by which mutations in cancer cells can lead to unregulated cell growth and differentiation?

<p>All of the above (D)</p> Signup and view all the answers

What is the estimated number of new cancer cases in the United States for the year 2024?

<p>Around 1.9 million new cases of cancer (C)</p> Signup and view all the answers

Which phase of the cell cycle is responsible for DNA synthesis?

<p>S phase (B)</p> Signup and view all the answers

What is the primary role of cyclins in the cell cycle?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT a characteristic of benign neoplasms?

<p>Ability to metastasize (A)</p> Signup and view all the answers

What is the primary difference between benign and malignant neoplasms in terms of cell differentiation?

<p>Benign neoplasms are well-differentiated, while malignant neoplasms are undifferentiated (D)</p> Signup and view all the answers

Which of the following is a characteristic of malignant neoplasms?

<p>Ability to metastasize (D)</p> Signup and view all the answers

What is the primary role of stem cells in cell differentiation?

<p>To differentiate into various cell types (A)</p> Signup and view all the answers

What is the meaning of the suffix '-oma' in the context of neoplasms?

<p>It is added to the parenchymal tissue type to denote the tumor name (B)</p> Signup and view all the answers

What is the primary difference between benign and malignant neoplasms in terms of growth rate?

<p>Benign neoplasms have a progressive and slow growth rate, while malignant neoplasms have a variable growth rate (B)</p> Signup and view all the answers

Which of the following is a characteristic of benign neoplasms?

<p>Expansion without invasion (B)</p> Signup and view all the answers

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