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Neoplasia Goldsmith Objectives

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20 Questions

What is the primary difference between benign and malignant tumors?

All of the above

Which of the following is NOT a characteristic of cancer cells?

Increased cell-cell adhesion

What is the role of proto-oncogenes in oncogenesis?

They encode growth factors or second messengers that stimulate cell growth

Which of the following is NOT a step in the cancer cell transformation process by chemicals?

Regression

What is the primary function of tumor suppressor genes (anti-oncogenes)?

Inhibit cell growth and differentiation

Which of the following is NOT a risk factor for cancer development?

Regular exercise

What is the primary cause of cancer cachexia?

Protein wasting

Which of the following is NOT a common treatment modality for cancer?

Gene therapy

What is the primary goal of targeted cancer therapy?

To target specific molecular pathways or mutations in cancer cells

What is the primary mechanism by which mutations in cancer cells can lead to unregulated cell growth and differentiation?

All of the above

What is the estimated number of new cancer cases in the United States for the year 2024?

Around 1.9 million new cases of cancer

Which phase of the cell cycle is responsible for DNA synthesis?

S phase

What is the primary role of cyclins in the cell cycle?

All of the above

Which of the following is NOT a characteristic of benign neoplasms?

Ability to metastasize

What is the primary difference between benign and malignant neoplasms in terms of cell differentiation?

Benign neoplasms are well-differentiated, while malignant neoplasms are undifferentiated

Which of the following is a characteristic of malignant neoplasms?

Ability to metastasize

What is the primary role of stem cells in cell differentiation?

To differentiate into various cell types

What is the meaning of the suffix '-oma' in the context of neoplasms?

It is added to the parenchymal tissue type to denote the tumor name

What is the primary difference between benign and malignant neoplasms in terms of growth rate?

Benign neoplasms have a progressive and slow growth rate, while malignant neoplasms have a variable growth rate

Which of the following is a characteristic of benign neoplasms?

Expansion without invasion

Learn about cancer incidence in the U.S., cell differentiation, growth factors, and their importance in neoplasia. Explore data on estimated new cancer cases by site and gender from the American Cancer Society.

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