43 Questions
Which pattern of follicles is characterized by the presence of well-defined nidi of small uniform cells?
Microfollicular
What is the definition of carcinoma in-situ?
Malignant cells involving the entire thickness of the epithelium without penetration of the basement membrane
What distinguishes dysplasia from hyperplasia and carcinoma in-situ?
Loss of organizational structure of cells
Which type of tumors may develop through lymphatic spread?
Breast carcinoma
What are paraneoplastic syndromes?
Nonmetastatic systemic effects that accompany malignant disease
What may be the first or most prominent manifestation of a cancer?
Paraneoplastic syndromes
Which type of tumors are favored through hematogenous spread?
Sarcomas
Which type of benign tumor may produce a microscopic or macroscopic finger-like pattern?
Papilloma
Which type of malignant tumor arises from mesenchymal tissue?
Sarcoma
What distinguishes hyperplasia from dysplasia?
Increased cell production
What is the characteristic feature of microfollicular pattern?
Presence of well-defined nidi of small uniform cells
What is the definition of neoplasia?
New growths of cells uncoordinated with normal tissues
What is the study of tumors called?
Oncology
What are the two basic components of a tumor?
Parenchyma and stroma
What determines the biological behavior of a tumor?
Parenchyma
What does the suffix '-oma' indicate in the nomenclature of tumors?
Tumor
What is the term for the extent to which the parenchymal cells of a tumor resemble their normal counterparts morphologically and functionally?
Differentiation
Which type of tumor is well differentiated and closely resembles their normal counterparts?
'Well differentiated'
What does 'pleomorphism' refer to in histological examination of a tumor?
'Variation in size'
What does 'anaplasia' refer to in the context of tumor differentiation?
'Poorly differentiated'
'Fibro + oma' in nomenclature indicates a tumor originating from which type of tissue?
'Fibrous tissue'
'Chondro + oma' in nomenclature indicates a tumor originating from which type of tissue?
'Cartilage'
'Leiomyo + oma' in nomenclature indicates a tumor originating from which type of tissue?
'Smooth muscle'
Malignant tumors are always well differentiated and closely resemble their normal counterparts.
False
Well-differentiated tumors closely resemble their normal counterparts morphologically and functionally.
True
Anaplasia refers to the extent to which the parenchymal cells of a tumor resemble their normal counterparts.
False
Pleomorphism in histological examination of a tumor refers to uniform cell size and shape.
False
Benign tumors have the potential to spread to distant sites in the body.
False
The biological behavior of a tumor is primarily determined by the stroma.
False
Oncology is the study of benign tumors only.
False
The suffix '-oma' in the nomenclature of tumors always indicates a malignant tumor.
False
Neoplasia refers to the uncoordinated growth of cells that is in harmony with normal tissues.
False
Malignant neoplasms cannot be locally excised and generally lead to patient survival.
False
Dysplasia always progresses to cancer?
False
Metastasis can only occur through lymphatic spread.
False
Pleomorphism refers to the loss of the organizational structure of cells.
False
Carcinoma in-situ involves penetration of the basement membrane.
False
Paraneoplastic syndromes are metastatic effects that accompany malignant disease.
False
Anaplasia refers to the extent to which parenchymal cells of a tumor resemble their normal counterparts.
False
Benign tumors always grow faster than malignant tumors.
False
Carcinoma can arise from mesenchymal tissue.
False
Abnormal mitotic spindles are a characteristic of benign tumors.
False
Chromatin clearing and margination are characteristics of well-differentiated tumors.
False
Study Notes
Tumor Characteristics
- The presence of well-defined nidi of small uniform cells characterizes a follicular pattern.
- Carcinoma in-situ is defined as a neoplasm that remains confined to the epithelium of origin without penetrating the basement membrane.
- Dysplasia is distinguished from hyperplasia and carcinoma in-situ by the presence of cytologic atypia and loss of normal tissue architecture.
Tumor Spread
- Tumors that develop through lymphatic spread are known as lymph node metastases.
- Paraneoplastic syndromes are systemic effects that accompany malignant disease, but are not directly related to the primary tumor.
Tumor Types
- Tumors favored through hematogenous spread are those that metastasize through the bloodstream.
- Benign tumors that produce a microscopic or macroscopic finger-like pattern are known as papillary tumors.
- Malignant tumors that arise from mesenchymal tissue are known as sarcomas.
Tumor Histology
- Hyperplasia is distinguished from dysplasia by the presence of normal tissue architecture.
- The characteristic feature of microfollicular pattern is the presence of small, uniform follicles.
- Pleomorphism refers to the variation in cell size and shape.
- Anaplasia refers to the loss of differentiation in tumor cells.
Neoplasia
- Neoplasia is defined as the uncoordinated growth of cells that is not in harmony with normal tissues.
- The study of tumors is called oncology.
Tumor Components
- The two basic components of a tumor are the parenchyma and stroma.
- The biological behavior of a tumor is primarily determined by the parenchyma.
Tumor Nomenclature
- The suffix '-oma' in the nomenclature of tumors indicates a benign tumor.
- 'Fibro + oma' in nomenclature indicates a tumor originating from fibrous tissue.
- 'Chondro + oma' in nomenclature indicates a tumor originating from cartilaginous tissue.
- 'Leiomyo + oma' in nomenclature indicates a tumor originating from smooth muscle tissue.
Take this quiz to test your understanding of neoplasia, tumors, and the study of oncology. Explore the differences between benign and malignant tumors, their characteristics, and their impact on patients.
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