Neoplasia and Tumor Growth Quiz BMS LAB
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Questions and Answers

Which pattern of follicles is characterized by the presence of well-defined nidi of small uniform cells?

  • Microfollicular (correct)
  • Normofollicular
  • Macrofollicular
  • Trabecular

What is the definition of carcinoma in-situ?

  • Increased cell production
  • Development of secondary implants discontinuous with the primary tumor
  • Localized growth without invasion
  • Malignant cells involving the entire thickness of the epithelium without penetration of the basement membrane (correct)

What distinguishes dysplasia from hyperplasia and carcinoma in-situ?

  • Intraepithelial malignancy without penetration of the basement membrane
  • Increased cell production
  • Loss of organizational structure of cells (correct)
  • Development of secondary implants discontinuous with the primary tumor

Which type of tumors may develop through lymphatic spread?

<p>Breast carcinoma (D)</p> Signup and view all the answers

What are paraneoplastic syndromes?

<p>Nonmetastatic systemic effects that accompany malignant disease (C)</p> Signup and view all the answers

What may be the first or most prominent manifestation of a cancer?

<p>Paraneoplastic syndromes (A)</p> Signup and view all the answers

Which type of tumors are favored through hematogenous spread?

<p>Sarcomas (B)</p> Signup and view all the answers

Which type of benign tumor may produce a microscopic or macroscopic finger-like pattern?

<p>Papilloma (A)</p> Signup and view all the answers

Which type of malignant tumor arises from mesenchymal tissue?

<p>Sarcoma (D)</p> Signup and view all the answers

What distinguishes hyperplasia from dysplasia?

<p>Increased cell production (B)</p> Signup and view all the answers

What is the characteristic feature of microfollicular pattern?

<p>Presence of well-defined nidi of small uniform cells (D)</p> Signup and view all the answers

What is the definition of neoplasia?

<p>New growths of cells uncoordinated with normal tissues (A)</p> Signup and view all the answers

What is the study of tumors called?

<p>Oncology (C)</p> Signup and view all the answers

What are the two basic components of a tumor?

<p>Parenchyma and stroma (A)</p> Signup and view all the answers

What determines the biological behavior of a tumor?

<p>Parenchyma (A)</p> Signup and view all the answers

What does the suffix '-oma' indicate in the nomenclature of tumors?

<p>Tumor (B)</p> Signup and view all the answers

What is the term for the extent to which the parenchymal cells of a tumor resemble their normal counterparts morphologically and functionally?

<p>Differentiation (D)</p> Signup and view all the answers

Which type of tumor is well differentiated and closely resembles their normal counterparts?

<p>'Well differentiated' (D)</p> Signup and view all the answers

What does 'pleomorphism' refer to in histological examination of a tumor?

<p>'Variation in size' (A)</p> Signup and view all the answers

What does 'anaplasia' refer to in the context of tumor differentiation?

<p>'Poorly differentiated' (C)</p> Signup and view all the answers

'Fibro + oma' in nomenclature indicates a tumor originating from which type of tissue?

<p>'Fibrous tissue' (D)</p> Signup and view all the answers

'Chondro + oma' in nomenclature indicates a tumor originating from which type of tissue?

<p>'Cartilage' (C)</p> Signup and view all the answers

'Leiomyo + oma' in nomenclature indicates a tumor originating from which type of tissue?

<p>'Smooth muscle' (A)</p> Signup and view all the answers

Malignant tumors are always well differentiated and closely resemble their normal counterparts.

<p>False (B)</p> Signup and view all the answers

Well-differentiated tumors closely resemble their normal counterparts morphologically and functionally.

<p>True (A)</p> Signup and view all the answers

Anaplasia refers to the extent to which the parenchymal cells of a tumor resemble their normal counterparts.

<p>False (B)</p> Signup and view all the answers

Pleomorphism in histological examination of a tumor refers to uniform cell size and shape.

<p>False (B)</p> Signup and view all the answers

Benign tumors have the potential to spread to distant sites in the body.

<p>False (B)</p> Signup and view all the answers

The biological behavior of a tumor is primarily determined by the stroma.

<p>False (B)</p> Signup and view all the answers

Oncology is the study of benign tumors only.

<p>False (B)</p> Signup and view all the answers

The suffix '-oma' in the nomenclature of tumors always indicates a malignant tumor.

<p>False (B)</p> Signup and view all the answers

Neoplasia refers to the uncoordinated growth of cells that is in harmony with normal tissues.

<p>False (B)</p> Signup and view all the answers

Malignant neoplasms cannot be locally excised and generally lead to patient survival.

<p>False (B)</p> Signup and view all the answers

Dysplasia always progresses to cancer?

<p>False (B)</p> Signup and view all the answers

Metastasis can only occur through lymphatic spread.

<p>False (B)</p> Signup and view all the answers

Pleomorphism refers to the loss of the organizational structure of cells.

<p>False (B)</p> Signup and view all the answers

Carcinoma in-situ involves penetration of the basement membrane.

<p>False (B)</p> Signup and view all the answers

Paraneoplastic syndromes are metastatic effects that accompany malignant disease.

<p>False (B)</p> Signup and view all the answers

Anaplasia refers to the extent to which parenchymal cells of a tumor resemble their normal counterparts.

<p>False (B)</p> Signup and view all the answers

Benign tumors always grow faster than malignant tumors.

<p>False (B)</p> Signup and view all the answers

Carcinoma can arise from mesenchymal tissue.

<p>False (B)</p> Signup and view all the answers

Abnormal mitotic spindles are a characteristic of benign tumors.

<p>False (B)</p> Signup and view all the answers

Chromatin clearing and margination are characteristics of well-differentiated tumors.

<p>False (B)</p> Signup and view all the answers

Study Notes

Tumor Characteristics

  • The presence of well-defined nidi of small uniform cells characterizes a follicular pattern.
  • Carcinoma in-situ is defined as a neoplasm that remains confined to the epithelium of origin without penetrating the basement membrane.
  • Dysplasia is distinguished from hyperplasia and carcinoma in-situ by the presence of cytologic atypia and loss of normal tissue architecture.

Tumor Spread

  • Tumors that develop through lymphatic spread are known as lymph node metastases.
  • Paraneoplastic syndromes are systemic effects that accompany malignant disease, but are not directly related to the primary tumor.

Tumor Types

  • Tumors favored through hematogenous spread are those that metastasize through the bloodstream.
  • Benign tumors that produce a microscopic or macroscopic finger-like pattern are known as papillary tumors.
  • Malignant tumors that arise from mesenchymal tissue are known as sarcomas.

Tumor Histology

  • Hyperplasia is distinguished from dysplasia by the presence of normal tissue architecture.
  • The characteristic feature of microfollicular pattern is the presence of small, uniform follicles.
  • Pleomorphism refers to the variation in cell size and shape.
  • Anaplasia refers to the loss of differentiation in tumor cells.

Neoplasia

  • Neoplasia is defined as the uncoordinated growth of cells that is not in harmony with normal tissues.
  • The study of tumors is called oncology.

Tumor Components

  • The two basic components of a tumor are the parenchyma and stroma.
  • The biological behavior of a tumor is primarily determined by the parenchyma.

Tumor Nomenclature

  • The suffix '-oma' in the nomenclature of tumors indicates a benign tumor.
  • 'Fibro + oma' in nomenclature indicates a tumor originating from fibrous tissue.
  • 'Chondro + oma' in nomenclature indicates a tumor originating from cartilaginous tissue.
  • 'Leiomyo + oma' in nomenclature indicates a tumor originating from smooth muscle tissue.

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