Neoplasia and Tumors
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Questions and Answers

Which stage of thyroid carcinoma has: marked pleomorphism, high nuclear to cytoplasmic ratios, hyperchromatic nuclei, abnormal nuclear contours, prominent nucleoli, and loss of normal polarity

  • papillary (conventional) - well differentiated
  • follicular - well diff
  • medullar - poorly differentiated (insular)
  • anaplastic - undifferentiated (correct)

What is the definition of dysplasia?

  • An intraepithelial malignancy in which malignant cells involve the entire thickness of the epithelium without penetration of the basement membrane
  • Loss of the organizational structure of cells (correct)
  • Increased cell production
  • Development of secondary implants discontinuous with the primary tumor

In what type of neoplasm does pleural, peritoneal cavities, and cerebral ventricles seeding occur?

  • Adenoma
  • Carcinoma (correct)
  • Sarcoma
  • Papilloma

Which tumor type is classified based on the basis of the cell of origin, microscopic pattern, and macroscopic pattern?

<p>Epithelial benign tumors (B)</p> Signup and view all the answers

what is paraneoplastic syndrome

<p>Rare disorder as a result of an abnormal immune system response to the tumor, rather than the direct effects of the tumor itself (C)</p> Signup and view all the answers

What is the distinct feature of carcinoma in-situ?

<p>Penetration of the basement membrane by malignant cells (C)</p> Signup and view all the answers

Which tumor arises from mesenchymal tissue?

<p>Sarcoma (C)</p> Signup and view all the answers

What is a characteristic feature of benign tumors?

<p>Usually grows slowly and is affected by blood supply and hormonal effects (B)</p> Signup and view all the answers

What is the study of tumors called?

<p>Oncology (A)</p> Signup and view all the answers

What is the main characteristic that distinguishes benign from malignant neoplasms?

<p>Nature of cellular differentiation (D)</p> Signup and view all the answers

What is the functional tissue component of a tumor called?

<p>Parenchyma (A)</p> Signup and view all the answers

What does the suffix '-oma' typically denote in tumor nomenclature?

<p>Type of cell (A)</p> Signup and view all the answers

What term is used to describe the variation in size and shape of cells within a tissue sample?

<p>Pleomorphism (C)</p> Signup and view all the answers

Which component of a tumor determines its biological behavior?

<p>Parenchyma (C)</p> Signup and view all the answers

What term refers to the extent to which the parenchymal cells of a tumor resemble their normal counterparts morphologically and functionally?

<p>Differentiation (B)</p> Signup and view all the answers

What does a high nuclear/cytoplasm ratio (N/C ratio) indicate in histological examination of a tumor?

<p>Anaplasia (C)</p> Signup and view all the answers

What does hyperchromasia indicate in histological examination of a tumor?

<p>Anaplasia (B)</p> Signup and view all the answers

Which neoplasm will remain localized and cannot spread to distant sites?

<p>Benign neoplasm (A)</p> Signup and view all the answers

Which of the following best describes neoplasia?

<p>Abnormal mass of autonomous cells (D)</p> Signup and view all the answers

What are the two basic components of a neoplasm as described in the text?

<p>Proliferating neoplastic cells and reactive stroma (A)</p> Signup and view all the answers

Which suffix is typically used for naming benign tumors?

<p>-oma (B)</p> Signup and view all the answers

In tumor nomenclature, which suffix is used for tumors arising from glandular epithelium?

<p>-carcinoma (D)</p> Signup and view all the answers

What is the term used for a tumor that shows variation in size and shape of cells within a tissue sample?

<p>Dysplastic tumor (C)</p> Signup and view all the answers

What is the term for a genetic disease caused by DNA mutations that are monoclonal in essence and inherited?

<p>Retinoblastoma (A)</p> Signup and view all the answers

Which of the following conditions is characterized by abnormal cells within a tissue or organ, leading to uncontrolled growth disregarding the normal rule of cell division?

<p>Anaplasia (B)</p> Signup and view all the answers

What does the suffix '-sarcoma' typically denote in tumor nomenclature?

<p>Mesenchymal neoplasm (C)</p> Signup and view all the answers

Which of the following features is a characteristic of invasive carcinoma?

<p>Locally invasive, infiltrating the surrounding normal tissues (D)</p> Signup and view all the answers

What term is used to describe the variation in size and shape of cells within a tissue sample?

<p>Pleomorphism (A)</p> Signup and view all the answers

Which condition involves loss of cellular uniformity and orientation, hyperchromatic nuclei, and increased mitosis?

<p>Anaplasia (A)</p> Signup and view all the answers

What is the term for the study of tumors?

<p>Oncology (B)</p> Signup and view all the answers

Which of the following is NOT commonly associated with paraneoplastic syndromes?

<p>Hypertension (D)</p> Signup and view all the answers

What term refers to the extent to which the parenchymal cells of a tumor resemble their normal counterparts morphologically and functionally?

<p>Differentiation (A)</p> Signup and view all the answers

In what type of neoplasm does pleural, peritoneal cavities, and cerebral ventricles seeding occur?

<p>Malignant tumors (cancerous) (A)</p> Signup and view all the answers

Which neoplasm will remain localized and cannot spread to distant sites?

<p>Basal cell carcinoma (C)</p> Signup and view all the answers

What is the functional tissue component of a tumor called?

<p>Parenchyma (C)</p> Signup and view all the answers

Which of the following is NOT considered an environmental factor that can induce cancer?

<p>Mutations in DNA replication (B)</p> Signup and view all the answers

What virus is a chief suspect for causing cervix cancer?

<p>Human papilloma virus (HPV) (A)</p> Signup and view all the answers

Which of the following is a physical carcinogen?

<p>UV rays (D)</p> Signup and view all the answers

What is the genetic change that can lead to uncontrolled cell division and cancer?

<p>Mutation in proto-oncogene (D)</p> Signup and view all the answers

What is the function of a tumor suppressor gene?

<p>Acts to regulate cell division (C)</p> Signup and view all the answers

Which type of tumor marker can be found in the blood, urine, stool, or other bodily fluids?

<p>Circulating markers (D)</p> Signup and view all the answers

What do tumor tissue markers help to do?

<p>Estimate prognosis (C)</p> Signup and view all the answers

What is the role of an oncogene in regulating normal cell division?

<p>Plays a role in regulating normal cell division (C)</p> Signup and view all the answers

What is the main characteristic of circulating tumor markers?

<p>Present in blood, urine, stool, or other bodily fluids (C)</p> Signup and view all the answers

What is the primary role of a tumor suppressor gene?

<p>Acts to regulate cell division (D)</p> Signup and view all the answers

What is the role of a proto-oncogene before it becomes mutated?

<p>Plays a role in regulating normal cell division (A)</p> Signup and view all the answers

Which type of marker is used to monitor whether the treatment has stopped working?

<p>Circulating markers (B)</p> Signup and view all the answers

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