Neonatal Sepsis

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Questions and Answers

Which group of neonates is most likely to have a rapid onset of sepsis?

  • Neonates born to mothers with a history of sepsis
  • Premature neonates (correct)
  • Full-term neonates
  • Neonates born via Cesarean section

How many newborns with early-onset sepsis present within 24 hours?

  • 50%
  • 5%
  • 15%
  • 85% (correct)

How is early-onset sepsis most commonly acquired by the neonate?

  • Hematogenous spread from an infected mother
  • Colonization of the birth canal
  • Transplacental spread from an infected mother
  • Ascending infection from the cervix (correct)

Which microorganisms are most commonly associated with early-onset sepsis?

<p>Group B Streptococcus (GBS) (B)</p> Signup and view all the answers

What trend has been observed in the incidence of GBS disease in early-onset sepsis?

<p>Decreasing incidence (C)</p> Signup and view all the answers

Flashcards

Which neonates have rapid sepsis?

Premature neonates are at higher risk.

Early-onset sepsis: how quickly?

85% of newborns with early-onset sepsis show symptoms within the first 24 hours.

How is early-onset sepsis acquired?

Most commonly acquired via ascending infection from the cervix.

Most common early-onset sepsis microorganism?

Group B Streptococcus (GBS).

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GBS early-onset sepsis trend?

The incidence of GBS disease has been decreasing.

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Study Notes

Sepsis in Neonates

  • Premature neonates are most likely to have a rapid onset of sepsis
  • In early-onset sepsis, 85% of newborns present within 24 hours
  • Early-onset sepsis is most commonly acquired by the neonate via vertical transmission from the maternal genital tract
  • Group B Streptococcus (GBS) and Escherichia coli (E. coli) are the microorganisms most commonly associated with early-onset sepsis
  • There has been a decreasing trend in the incidence of GBS disease in early-onset sepsis, likely due to the increased use of intrapartum antibiotic prophylaxis

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