Neisseria Meningitidis: Clinical Significance

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What is the primary mechanism by which Neisseria meningitides causes severe septicemia and shock?

Antibody-dependent complement activation
Invasion of the bloodstream by Neisseria meningitides
Production of exotoxin
Release of lipopolysaccharide endotoxin (correct)

What is the primary goal of vaccination against Neisseria meningitides?

To prevent colonization of the nasopharynx
To induce herd immunity in the population (correct)
To eradicate the bacteria from the environment
To reduce the severity of disease symptoms

What is the primary purpose of using Thayer-Martin medium in the diagnosis of Neisseria meningitides?

To identify the capsular polysaccharides
To select for Gram-negative diplococci (correct)
To enhance the growth of Neisseria meningitides
To inhibit the growth of contaminants

Which of the following is the most common way to detect asymptomatic carriers of Neisseria meningitides?

Culturing swabs from the nasopharyngeal region (A) Signup and view all the answers

What is the primary mode of transmission of Acinetobacter in hospitals?

Through contaminated medical equipment (C) Signup and view all the answers

What is the drug of choice for the treatment of Neisseria meningitides infection?

Penicillin (D) Signup and view all the answers

What is the gold standard for the diagnosis of systemic meningococcal infection?

Isolation of N. meningitidis (B) Signup and view all the answers

What is the primary mechanism of Neisseria meningitidis attachment to nasopharyngeal mucosa?

Pili (B) Signup and view all the answers

What is the primary function of IgA protease in N. meningitidis?

Cleavage of IgA antibodies (B) Signup and view all the answers

Which of the following is a risk factor for Neisseria meningitidis infection?

Recent viral or mycoplasma upper respiratory tract infection (A) Signup and view all the answers

Which serogroups of N. meningitidis are responsible for most cases of meningococcal disease?

A, B, and C (B) Signup and view all the answers

What is the most effective way to prevent N. meningitidis infection?

Vaccination against N. meningitidis (B) Signup and view all the answers

What is the primary benefit of using automated susceptibility testing in identifying A. baumannii?

To guide the physician in making appropriate treatment decisions (D) Signup and view all the answers

What is the primary role of pulsed-field gel electrophoresis (PFGE) in A. baumannii diagnosis?

To differentiate between strains of bacteria (B) Signup and view all the answers

What is the primary advantage of 16s rDNA sequencing in A. baumannii diagnosis?

It provides information on the genotype of the bacteria (D) Signup and view all the answers

What is the primary role of molecular methods in hospital infection control?

To identify the source of hospital-acquired infections (D) Signup and view all the answers

What is the primary advantage of using molecular methods in Acinetobacter infections?

They provide information on the genotype of the bacteria (D) Signup and view all the answers

What is the primary role of molecular testing in the diagnosis of A. baumannii infections?

To identify the genotype of the bacteria and guide infection control measures (C) Signup and view all the answers