12 Questions
What is the main function of natural killer cells?
Killing altered cells
How do natural killer cells recognize their targets?
Without the specificity of lymphocytes
Which process involves the formation of a phagosome?
Ingestion
What is responsible for killing microbes during phagocytosis?
Lysosomes
Which leukocyte is the first to move from blood to tissue during an inflammatory response?
Neutrophils
What is the major component of pus?
Neutrophils
Which cells use pattern recognition receptors (PRRs) to 'see' pathogen-associated molecular patterns (PAMPs)?
Dendritic Cells
What happens when a PRR binds a PAMP in phagocytosis?
Stimulation of pro-inflammatory cytokine secretion
What is the role of resident macrophages in the initial response to tissue damage?
Phagocytose pathogens and release cytokines
Which of the following is NOT a function of inflammation?
Activate an adaptive immune response
How do phagocytes contribute to the immune response?
Phagocytose pathogens and present antigens
What is the purpose of vasodilation and increased permeability of blood vessels during inflammation?
To prevent spread of infection to other tissues
Learn about natural killer cells, a unique group of defensive cells that do not require the specificity of lymphocytes to recognize targets. Discover their ability to spontaneously kill tumor or virally-infected cells through perforin, granzyme, and cytokines.
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