Podcast
Questions and Answers
Which type of interactions are primarily responsible for the tertiary structure of myoglobin and hemoglobin?
Which type of interactions are primarily responsible for the tertiary structure of myoglobin and hemoglobin?
- Covalent interactions
- Van der Waals interactions
- Ionic interactions
- Hydrophobic interactions (correct)
In the binding of oxygen to heme iron in hemoglobin, what is the state of iron that is important for this process?
In the binding of oxygen to heme iron in hemoglobin, what is the state of iron that is important for this process?
- Oxidized state
- Reduced state
- Ferrous state (correct)
- Ferric state
Which molecule binds to both adult hemoglobin and fetal hemoglobin, affecting their oxygenation properties?
Which molecule binds to both adult hemoglobin and fetal hemoglobin, affecting their oxygenation properties?
- 2,3-bisphosphoglycerate (correct)
- Carbon monoxide
- Oxygen
- Carbon dioxide
What is the primary therapeutic approach for carbon monoxide poisoning due to its competitive interaction with oxygen in hemoglobin?
What is the primary therapeutic approach for carbon monoxide poisoning due to its competitive interaction with oxygen in hemoglobin?
Which factor does not affect the oxygenation of hemoglobin in the lungs and in the tissues?
Which factor does not affect the oxygenation of hemoglobin in the lungs and in the tissues?
What is the main chemical difference between hemoglobin and methemoglobin?
What is the main chemical difference between hemoglobin and methemoglobin?
What is the role of the distal histidine in myoglobin and hemoglobin?
What is the role of the distal histidine in myoglobin and hemoglobin?
Which statement describes the function of the proximal histidine in myoglobin and hemoglobin?
Which statement describes the function of the proximal histidine in myoglobin and hemoglobin?
What causes methemoglobin formation?
What causes methemoglobin formation?
What is the role of heme in cytochromes?
What is the role of heme in cytochromes?
What is the primary function of myoglobin?
What is the primary function of myoglobin?
What does a lower P50 indicate for hemoglobin's affinity for oxygen?
What does a lower P50 indicate for hemoglobin's affinity for oxygen?
Which of the following binds to hemoglobin in the T form, shifting the equilibrium between the R and T states toward the T form?
Which of the following binds to hemoglobin in the T form, shifting the equilibrium between the R and T states toward the T form?
What is the primary effect of carbon monoxide poisoning on hemoglobin?
What is the primary effect of carbon monoxide poisoning on hemoglobin?
In what form does methemoglobin contain iron?
In what form does methemoglobin contain iron?
What is the main difference between alpha thalassemia and beta thalassemia?
What is the main difference between alpha thalassemia and beta thalassemia?
What is the abnormality associated with Hemoglobin Gun Hill?
What is the abnormality associated with Hemoglobin Gun Hill?
In uncontrolled diabetes, what happens to the levels of HbA1c compared to normal?
In uncontrolled diabetes, what happens to the levels of HbA1c compared to normal?
What does hereditary persistence of fetal hemoglobin (HPFH) refer to?
What does hereditary persistence of fetal hemoglobin (HPFH) refer to?
What is the impact of CO poisoning on hemoglobin?
What is the impact of CO poisoning on hemoglobin?