Myocardial Infarction Manifestations and Pathophysiology

Macrophages, phagocytosis

Atherosclerosis, fatty streaks

Immune mediated

<p>None</p> Signup and view all the answers

<p>Mural thrombus</p> Signup and view all the answers

<p>Injured Endothelial Cells and Macrophages Produce Free Radicals</p> Signup and view all the answers

<p>Foam cells, some of which have died and released lipid</p> Signup and view all the answers

<p>Disruption, with superimposed thrombus, rupture</p> Signup and view all the answers

<p>Free radicals</p> Signup and view all the answers

<p>Smooth muscle proliferation, deposition of collagen and other extracellular matrix, and extracellular lipid deposition</p> Signup and view all the answers

<p>The outcome depends on the location/severity of occlusion, duration of occlusion, collateral circulation, blood pressure, and heart rate.</p> Signup and view all the answers

<p>The manifestations include angina pectoris, acute myocardial infarction, sudden cardiac death syndrome, chronic IHD, cardiac arrhythmias.</p> Signup and view all the answers

<p>Transmural myocardial infarction involves full thickness of the myocardium, while subendocardial myocardial infarction is limited to the inner 1/3 of the wall.</p> Signup and view all the answers

<p>The consequences and complications include death (arrhythmia), contractile dysfunction (acute cardiac failure, chronic congestive failure), arrhythmias, and myocardial rupture (haemopericardium/tamponade).</p> Signup and view all the answers

<p>Cell death (myocyte necrosis) leads to the release of cytoplasmic proteins into serum, such as Troponin, which can be measured to confirm diagnosis.</p> Signup and view all the answers