Myelodysplastic Syndrome (MDS) Symptoms
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Questions and Answers

What is the most common age group for Myelodysplastic syndrome (MDS)?

  • 40-50 years
  • 50-60 years
  • >70 years (correct)
  • 60-70 years

    • What are the common symptoms related to anemia in MDS?

  • Fever and arthritis
  • Fatigue and decreased exercise tolerance (correct)
  • Bleeding and easy bruising
  • Recurrent infections

    • What is a predisposing factor for MDS in younger patients?

  • Chronic myelomonocytic leukaemia
  • Fanconi's syndrome (correct)
  • Acute lymphoblastic leukemia (ALL)
  • Splenomegaly

    • What is the significance of splenomegaly, hepatomegaly, and lymphadenopathy in MDS?

    <p>They are usually seen only in association with chronic myelomonocytic leukaemia</p> Signup and view all the answers

    What is the incidence pattern of acute lymphoblastic leukemia (ALL)?

    <p>A second peak around the age of 35 years, and a third peak at the age of 80 to 84 years</p> Signup and view all the answers

    What are the common symptoms associated with cytopenias in ALL?

    <p>Recurrent infections</p> Signup and view all the answers

    In MDS, what is the significance of autoimmune manifestations?

    <p>They are less common but possible</p> Signup and view all the answers

    What are the common symptoms of thrombocytopenia in ALL?

    <p>Bleeding and easy bruising</p> Signup and view all the answers

    What are the common symptoms of neutropenia in ALL?

    <p>Recurrent infections, which may cause fever.</p> Signup and view all the answers

    Which disease should be considered in younger patients who have had chemotherapy or who have a predisposing factor such as Fanconi's syndrome?

    <p>Myelodysplastic syndrome (MDS)</p> Signup and view all the answers

    Which of the following is a common autoimmune manifestation in Myelodysplastic syndrome (MDS)?

    <p>Rash and joint pain</p> Signup and view all the answers

    What is a significant difference in the presentation of acute lymphoblastic leukemia (ALL) compared to Myelodysplastic syndrome (MDS)?

    <p>ALL usually presents with signs and symptoms for only a few weeks prior to diagnosis</p> Signup and view all the answers

    What is a potential predisposing factor for Myelodysplastic syndrome (MDS) in younger patients?

    <p>Fanconi's syndrome</p> Signup and view all the answers

    What age group has a second peak in the incidence of acute lymphoblastic leukemia (ALL)?

    <p>35 years</p> Signup and view all the answers

    What are the common symptoms associated with cytopenias in Myelodysplastic syndrome (MDS)?

    <p>Easy bruising and bleeding</p> Signup and view all the answers

    Which of the following is usually seen only in association with chronic myelomonocytic leukaemia under the FAB Cooperative Group classification system for Myelodysplastic syndrome (MDS)?

    <p>Splenomegaly, hepatomegaly, and lymphadenopathy</p> Signup and view all the answers

    In Myelodysplastic syndrome (MDS), what are the common symptoms related to anemia?

    <p>Fatigue and light-headedness</p> Signup and view all the answers

    What is a possible manifestation of acute illness in Myelodysplastic syndrome (MDS)?

    <p>Rash and joint pain</p> Signup and view all the answers

    What are the common symptoms associated with thrombocytopenia in acute lymphoblastic leukemia (ALL)?

    <p>Easy bruising and bleeding</p> Signup and view all the answers

    In acute lymphoblastic leukemia (ALL), what are the common symptoms related to neutropenia?

    <p>Recurrent infections and fever</p> Signup and view all the answers

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