Questions and Answers
What is the characteristic of megakaryoblasts in Acute Megakaryoblastic Leukemia?
Lack of MPO
What is the age range for Acute Megakaryoblastic Leukemia associated with Down syndrome?
Before the age of 5
What is the primary complication of Myelodysplastic Syndromes?
Infection or bleeding
What is the characteristic of bone marrow in Myelodysplastic Syndromes?
Signup and view all the answers
What is the primary driver of Chronic Myeloid Leukemia (CML)?
Signup and view all the answers
What is the first line treatment for Chronic Myeloid Leukemia (CML)?
Signup and view all the answers
What is the characteristic feature of the bone marrow in Myelodysplastic Syndromes?
Signup and view all the answers
What is the percentage of Myelodysplastic Syndromes cases that progress to Acute Myeloid Leukemia?
Signup and view all the answers
What is the term for a chronically enlarged spleen that removes excessive numbers of formed blood elements, leading to anemia, leukopenia, or thrombocytopenia?
Signup and view all the answers
What is the typical appearance of megakaryocytes in Myelodysplastic Syndromes?
Signup and view all the answers
What is the primary defect in Myelodysplastic Syndromes?
Signup and view all the answers
What is the term for a group of clonal stem cell disorders characterized by maturation defects and ineffective hematopoiesis?
Signup and view all the answers
What is a characteristic of myeloproliferative neoplasms?
Signup and view all the answers
What is the average age of onset for Acute Myeloid Leukemia (AML)?
Signup and view all the answers
What is the hallmark of Auer rod AML?
Signup and view all the answers
What is the genetic abnormality associated with Acute Promyelocytic Leukemia (APL)?
Signup and view all the answers
What is the treatment for Acute Promyelocytic Leukemia (APL)?
Signup and view all the answers
What is a characteristic of acute monocytic leukemia?
Signup and view all the answers