Mycobacterium Tuberculosis - TB Corral Quiz
24 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary characteristic of the GHON complex seen in primary tuberculosis infection?

  • Formation of caseating granulomas in the lung parenchyma
  • Involvement of the right middle lung lobe
  • Visual calcification of lung parenchyma and hilar lymph nodes on chest X-ray (correct)
  • Presence of red cactus fruit near the hilum

What is the significance of the 'millet seed' imagery in the context of tuberculosis?

  • It symbolizes the granulomatous lesions formed in the macrophages during primary infection
  • It represents the dissemination of tuberculosis to multiple organs, leading to miliary TB (correct)
  • It denotes the reactivation of tuberculosis, with the 'seeds' pouring out of the macrophage 'cart'
  • It indicates the progression of the disease to a latent state, like 'sleeping seeds'

Why is screening for latent tuberculosis infection important before starting a TNF-alpha inhibitor?

  • TNF-alpha inhibitors can lead to the development of miliary tuberculosis
  • TNF-alpha inhibitors can cause the formation of caseating granulomas
  • TNF-alpha inhibitors can reactivate latent tuberculosis infection (correct)
  • TNF-alpha inhibitors can cause the immune system to become more susceptible to tuberculosis

What is the significance of the 'right upper lobe' in the context of tuberculosis reactivation?

<p>Reactivation of tuberculosis is more common in the right upper lobe due to the presence of more oxygen-rich alveoli (B)</p> Signup and view all the answers

What is the significance of the 'Pott's disease' in the context of tuberculosis?

<p>Pott's disease is a form of extrapulmonary tuberculosis that affects the spinal column (A)</p> Signup and view all the answers

What is the significance of the 'PPD' (Mantoux) test in the diagnosis of tuberculosis?

<p>The PPD test is a measure of the zone of induration, which is used to determine the risk of tuberculosis infection (A)</p> Signup and view all the answers

What is the primary reason for the acid-fast staining property of Mycobacterium tuberculosis?

<p>The high concentration of mycolic acids (A)</p> Signup and view all the answers

Which medium is typically used for the growth of Mycobacterium tuberculosis in the laboratory?

<p>Lowenstein-Jensen medium (C)</p> Signup and view all the answers

What is the primary mode of transmission for Mycobacterium tuberculosis?

<p>Respiratory droplets (C)</p> Signup and view all the answers

Which virulence factor of Mycobacterium tuberculosis is responsible for its serpentine cord formation?

<p>Cord factor (trehalose dimycolate) (C)</p> Signup and view all the answers

What is the primary mechanism by which Mycobacterium tuberculosis evades destruction within macrophages?

<p>Prevention of phagosome-lysosome fusion (D)</p> Signup and view all the answers

What type of immune response is primarily responsible for the formation of granulomas in tuberculosis?

<p>Type IV hypersensitivity (cell-mediated immunity) (C)</p> Signup and view all the answers

Which of the following is the primary reason for the acid-fast staining property of Mycobacterium tuberculosis?

<p>The high concentration of mycolic acids in the cell wall (A)</p> Signup and view all the answers

What is the primary mechanism by which Mycobacterium tuberculosis evades destruction within macrophages?

<p>Inhibition of phagosome-lysosome fusion by sulfatides (D)</p> Signup and view all the answers

What is the significance of the 'cord factor' (trehalose dimycolate) in the pathogenesis of tuberculosis?

<p>It promotes the formation of a serpentine cord structure, which is a virulence factor (D)</p> Signup and view all the answers

Which medium is typically used for the growth of Mycobacterium tuberculosis in the laboratory?

<p>Lowenstein-Jensen medium (C)</p> Signup and view all the answers

What is the primary characteristic of the GHON complex seen in primary tuberculosis infection?

<p>Formation of a granuloma in the lung parenchyma (A)</p> Signup and view all the answers

Why is screening for latent tuberculosis infection important before starting a TNF-alpha inhibitor?

<p>To prevent the reactivation of latent tuberculosis infection (A)</p> Signup and view all the answers

What does the 'cactus with holes in the middle lobe' represent?

<p>Primary tuberculosis infection affecting the middle lobe of the lungs (B)</p> Signup and view all the answers

What is the significance of the 'broken carts' imagery?

<p>It represents the formation of granulomas due to the breakdown of macrophages (C)</p> Signup and view all the answers

What does the 'sick child in a burlap sack' symbolize?

<p>The primary symptoms of tuberculosis infection in children (D)</p> Signup and view all the answers

What is the significance of the 'guy strapped to barrels of TNF'?

<p>It represents the reactivation of latent tuberculosis due to immunosuppression and inhibition of TNF-alpha (B)</p> Signup and view all the answers

What does the 'right cactus with holes in the upper lung' represent?

<p>Reactivation of tuberculosis infection affecting the right upper lobe of the lungs (D)</p> Signup and view all the answers

What does the 'shovel with dirt' symbolize?

<p>The use of the purified protein derivative (PPD) skin test for diagnosing tuberculosis (B)</p> Signup and view all the answers

More Like This

Tuberculosis (TB) Quiz
10 questions

Tuberculosis (TB) Quiz

CostSavingDatePalm avatar
CostSavingDatePalm
Anti-TB drugs
23 questions

Anti-TB drugs

FelicitousCognition avatar
FelicitousCognition
Use Quizgecko on...
Browser
Browser