Mycobacteria Growth and Culturing Quiz
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Questions and Answers

What is the term for when primary tuberculosis heals without causing disease?

  • Latent infection (correct)
  • Active bacteria
  • Hematogenous focus
  • Fibrosis infection

Which of the following is a risk factor for tuberculosis reactivation?

  • Intravenous drug use
  • Being a health-care worker
  • Having a Ghon focus in the lower lung
  • Smoking (correct)

In approximately what percentage of cases do those with latent infection progress to active disease (reactivation) later on?

  • 15%
  • 1%
  • 5%
  • 10% (correct)

What type of tuberculosis occurs with a cavity in the upper lobes?

<p>Secondary tuberculosis (C)</p> Signup and view all the answers

Which drug type poses a risk factor for tuberculosis reactivation?

<p>Corticosteroids (D)</p> Signup and view all the answers

What is the term used for the progression from latent infection to active disease?

<p>Reactivation (A)</p> Signup and view all the answers

What is the main mode of transmission of tuberculosis?

<p>Aerosols generated by coughing of smear-positive individuals (B)</p> Signup and view all the answers

What percentage of people are infected by aerosols produced by coughing of smear-negative individuals?

<p>20% (D)</p> Signup and view all the answers

In which type of countries does Mycobacterium bovis cause tuberculosis in humans?

<p>Both developed and underdeveloped countries (D)</p> Signup and view all the answers

Who is at the highest risk of tuberculosis infection and disease?

<p>Elderly, malnourished individuals (B)</p> Signup and view all the answers

What is the most common site of infection for Mycobacterium tuberculosis?

<p>Lungs (B)</p> Signup and view all the answers

Which group of individuals in the US is mostly associated with cases of reactivation tuberculosis?

<p>Elderly, malnourished men (C)</p> Signup and view all the answers

What is the reason why cultures of clinical specimens for M.tuberculosis must be held for 6 to 8 weeks before being recorded as negative?

<p>M.tuberculosis grows slowly (A)</p> Signup and view all the answers

Why are dyes like malachite green included in the media used for culturing Mycobacteria?

<p>To inhibit normal flora in sputum samples (C)</p> Signup and view all the answers

Which specific fatty acids in the cell wall of M.tuberculosis contribute to its acid-fast property?

<p>Long-chain fatty acids (D)</p> Signup and view all the answers

What is the correlation between Cord factor (trehalose dimycolate) and the virulence of Mycobacteria?

<p>Virulent strains exhibit a serpentine cordlike growth pattern (C)</p> Signup and view all the answers

Which lipid located in the bacterial cell wall of Mycobacteria is essential for pathogenesis in the lung?

<p>Phthiocerol dimycocerosate (C)</p> Signup and view all the answers

Why does NaOH destroy unwanted bacteria, human cells, and mucus but not Mycobacteria?

<p>Mycobacteria have a thick cell wall with mycolic acids (C)</p> Signup and view all the answers

What are the main symptoms of pulmonary TB?

<p>Cough and hemoptysis (B)</p> Signup and view all the answers

Which region is most commonly involved in gastrointestinal TB?

<p>Ileocecal (C)</p> Signup and view all the answers

What is a characteristic chest X-ray finding in reactivation TB of the lung?

<p>Upper lobe infiltrate with or without a cavity (D)</p> Signup and view all the answers

Which symptom is characteristic of oropharyngeal TB?

<p>Painless ulcer (A)</p> Signup and view all the answers

What is a common manifestation of renal tuberculosis?

<p>Flank pain and hematuria (D)</p> Signup and view all the answers

What is Mycobacteria Miliary TB characterized by?

<p>Multiple disseminated lesions resembling millet seeds (C)</p> Signup and view all the answers

What is the main determinant of whether overt tuberculosis disease occurs?

<p>Adequacy of the host's cell-mediated immune response (B)</p> Signup and view all the answers

Which staining method is commonly used for rapid screening purposes to detect M.tuberculosis?

<p>Auramine stain (B)</p> Signup and view all the answers

What type of infections are most M.tuberculosis infections initially?

<p>Latent infections (D)</p> Signup and view all the answers

Which enzyme isolated from fireflies is used in the luciferase assay to detect drug-resistant organisms?

<p>Luciferase (B)</p> Signup and view all the answers

What percentage of 'smear-negative' samples are found to be 'culture-positive'?

<p>50% (A)</p> Signup and view all the answers

Why is multidrug therapy used during tuberculosis treatment?

<p>To prevent the emergence of drug-resistant mutants (A)</p> Signup and view all the answers

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