29 Questions
What is the primary component of the cell wall of Mycobacterium tuberculosis?
N-glycolylmuramic acid
What is the optimal pH range for the growth of Mycobacterium tuberculosis?
6.5 - 6.8
Which of the following is NOT a characteristic of Mycobacterium tuberculosis?
Spore-forming
What is the generation time of Mycobacterium tuberculosis?
>12 hours
Which of the following is a rapid-growing mycobacterium?
Mycobacterium fortuitum
What is the optimal temperature for the growth of Mycobacterium tuberculosis?
35-37°C
What is the primary means of transmission of Mycobacterium tuberculosis?
Inhalation of airborne droplet nuclei
Which of the following is a common symptom of tuberculosis in the spine?
Severe back pain
What is the primary method of diagnosis for pulmonary tuberculosis?
Tuberculin test
Which of the following is a risk factor for developing tuberculosis?
Malnourished patients
What is the characteristic feature of Miliary tuberculosis?
Millet-seed-like granuloma formation in various organs
What is the term used to describe the sulfates attached to the disaccharide (trehalose) in Mycoside Cord Factor?
Sulfides
Which of the following Mycobacterium species has been isolated from tuberculosis patients in both immunocompetent and immunocompromised individuals?
Mycobacterium microti
What is the primary function of the most common virulence factor for M.tuberculosis?
Activating the protective cellular immune system
What is the characteristic appearance of rough colonies of M.tuberculosis?
Curved strands of bacilli exhibiting 'cording'
What is the purpose of the BCG strain of Mycobacterium bovis?
To vaccinate newborns against tuberculosis
What is the mode of transmission of Mycobacterium bovis to humans?
Through contaminated milk from infected cows
What is the characteristic of Mycobacterium bovis growth on Egg-based media?
Slow growing, small, and non-pigmented
What is the primary function of albumin in serum agar-based media?
to protect AFB against toxic agents in the culture media
Which medium is specifically designed for heavily contaminated specimens?
Petragnani medium
What is the name of the oxygen sensor used in the MGIT 960 system?
Fluorescence quenching-based oxygen sensor
Which of the following inhibitory agents is NOT used in Middlebrook 7H11 medium?
Trimethoprim lactate
What is the primary advantage of the BACTEC 12B system?
Reduced processing time for the isolation of AFB
What is the name of the test used for extrapulmonary specimens?
XPERT MTB/RIF test
Which of the following species of Mycobacterium is known to produce yellow to orange pigmented colonies even without light exposure?
M. xenopi
What is the most common site of colonization by Mycobacterium avium complex?
Gastrointestinal tract
What is the growth rate of Mycobacterium xenopi?
10-21 days
Which biochemical test is variable in Mycobacterium avium complex?
Pyrazinamidase
What is the major species of Mycobacterium avium complex?
M. avium and M. intracellulare
Test your knowledge of Mycobacteria, including Mycobacterium tuberculosis complex. Learn about their characteristics, cell wall composition, and growth requirements.
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