Myasthenia Gravis Overview
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Questions and Answers

Which muscles are most commonly affected by myasthenia gravis?

  • Muscles of the chest and shoulders
  • Muscles of the arms and legs
  • Muscles of the eyes, face, and swallowing (correct)
  • Muscles of the back and abdomen
  • What is the primary cause of myasthenia gravis?

  • Excessive production of acetylcholinesterase
  • Genetic mutations in muscle cells
  • Deficiency of immunoglobulin G1 (IgG1) and IgG3 antibodies
  • Antibodies that block or destroy nicotinic acetylcholine receptors (correct)
  • How is myasthenia gravis diagnosed?

  • Blood tests for specific antibodies, edrophonium test, or nerve conduction study (correct)
  • Urinalysis for acetylcholine levels
  • MRI scan of the brain
  • X-ray of the chest
  • What type of medications are commonly used to treat myasthenia gravis?

    <p>Acetylcholinesterase inhibitors</p> Signup and view all the answers

    In what cases may surgical removal of the thymus improve symptoms of myasthenia gravis?

    <p>When the patient has a large thymus or develops a thymoma</p> Signup and view all the answers

    What is a common symptom of cricopharyngeal spasm?

    <p>Sensation of a 'lump' in the back of the throat</p> Signup and view all the answers

    What exacerbates the symptoms of cricopharyngeal spasm?

    <p>Stress</p> Signup and view all the answers

    What happens to the sphincters in the esophagus when one swallows?

    <p>They relax to allow food to pass through</p> Signup and view all the answers

    What is a potential cause of cricopharyngeal spasm according to psychiatry assumptions?

    <p>Low levels of serotonin</p> Signup and view all the answers

    What is a distinguishing feature of cricopharyngeal spasm compared to other conditions?

    <p>The sensation of 'lump' is constant and severe</p> Signup and view all the answers

    Study Notes

    Myasthenia Gravis

    • The most commonly affected muscles by myasthenia gravis are those involved in facial expressions, swallowing, and eye movements.
    • The primary cause of myasthenia gravis is an autoimmune disorder, where the body's immune system mistakenly attacks the receptors for a neurotransmitter called acetylcholine.
    • Myasthenia gravis is diagnosed through a combination of physical examination, medical history, and diagnostic tests, such as electromyography (EMG) and edrophonium testing.

    Treatment of Myasthenia Gravis

    • Medications commonly used to treat myasthenia gravis include anticholinesterase agents, such as pyridostigmine, and immunosuppressive drugs, such as prednisone and azathioprine.

    Thymus Removal

    • Surgical removal of the thymus may improve symptoms of myasthenia gravis in certain cases, particularly those with thymoma (a tumor of the thymus).

    Cricopharyngeal Spasm

    • A common symptom of cricopharyngeal spasm is difficulty swallowing, characterized by a feeling of food sticking in the throat.
    • Cricopharyngeal spasm symptoms can be exacerbated by swallowing solid foods, eating too quickly, or experiencing stress.
    • When one swallows, the upper esophageal sphincter (UES) relaxes, and the lower esophageal sphincter (LES) opens, allowing food to pass through the esophagus.
    • According to psychiatry assumptions, a potential cause of cricopharyngeal spasm is anxiety or stress.
    • A distinguishing feature of cricopharyngeal spasm compared to other conditions is the sudden, brief, and repeated contractions of the UES, which can be detected through electromyography (EMG) or manometry.

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    Description

    Test your knowledge about the long-term neuromuscular junction disease known as Myasthenia Gravis (MG) which causes skeletal muscle weakness, particularly in the eyes, face, and swallowing muscles. Learn about its symptoms, onset, and association with autoimmune response.

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