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Neuromuscular Junction Pathophysiology Quiz

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Neuromuscular Junction Pathophysiology Quiz

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Questions and Answers

What is the mechanism of action of curare-like drugs?

Enhancing the release of inhibitory neurotransmitters

Inhibiting the production of acetylcholine

Stimulating muscle contraction

Blocking nicotinic ACh receptors on the postsynaptic membrane (correct)

How does Clostridium Tetani toxin lead to muscle spasms in tetanus?

Stimulates the release of excitatory neurotransmitters in the brain

Increases the production of acetylcholine at the neuromuscular junction

Inhibits the transmission of nerve impulses to the muscles

Blocks the release of inhibitory neurotransmitters in the spinal cord (correct)

What is the effect of curare-like drugs on muscle function?

Promotes muscle growth

Increases muscle flexibility

Induces muscle paralysis (correct)

Reduces muscle sensitivity to pain

What is the source of tetanus toxin?

Clostridium tetani, a bacterium found in soil and dust (D) Signup and view all the answers

What is a characteristic feature of tetanus?

Sustained and painful muscle contractions (A) Signup and view all the answers

What preventive measure is crucial for tetanus?

Tetanus vaccination (A) Signup and view all the answers

What is the pathophysiology of tetanus toxin action?

Blocks the release of inhibitory neurotransmitters in the spinal cord (C) Signup and view all the answers

What is the effect of curare-like drugs during surgical procedures?

Facilitates intubation and muscle relaxation (D) Signup and view all the answers

What is the primary pathophysiological mechanism in Myasthenia Gravis (MG)?

Autoimmune attack on acetylcholine receptors (B) Signup and view all the answers

What is the main effect of Botulinum Toxin on neuromuscular transmission?

Inhibition of acetylcholine release (D) Signup and view all the answers

What is the consequence of reduced effective density of acetylcholine receptors in MG?

Impaired signal transmission and muscle weakness (A) Signup and view all the answers

Which muscles are particularly affected in Myasthenia Gravis?

Muscles controlling eye and facial movements, chewing, and swallowing (B) Signup and view all the answers

What is the source of Botulinum Toxin?

Clostridium botulinum bacteria (D) Signup and view all the answers

How does Botulinum Toxin cause muscle paralysis?

Blocking of acetylcholine receptors (A) Signup and view all the answers