Neuromuscular Junction Pathophysiology Quiz
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Questions and Answers

What is the mechanism of action of curare-like drugs?

  • Enhancing the release of inhibitory neurotransmitters
  • Inhibiting the production of acetylcholine
  • Stimulating muscle contraction
  • Blocking nicotinic ACh receptors on the postsynaptic membrane (correct)

How does Clostridium Tetani toxin lead to muscle spasms in tetanus?

  • Stimulates the release of excitatory neurotransmitters in the brain
  • Increases the production of acetylcholine at the neuromuscular junction
  • Inhibits the transmission of nerve impulses to the muscles
  • Blocks the release of inhibitory neurotransmitters in the spinal cord (correct)

What is the effect of curare-like drugs on muscle function?

  • Promotes muscle growth
  • Increases muscle flexibility
  • Induces muscle paralysis (correct)
  • Reduces muscle sensitivity to pain

What is the source of tetanus toxin?

<p>Clostridium tetani, a bacterium found in soil and dust (D)</p> Signup and view all the answers

What is a characteristic feature of tetanus?

<p>Sustained and painful muscle contractions (A)</p> Signup and view all the answers

What preventive measure is crucial for tetanus?

<p>Tetanus vaccination (A)</p> Signup and view all the answers

What is the pathophysiology of tetanus toxin action?

<p>Blocks the release of inhibitory neurotransmitters in the spinal cord (C)</p> Signup and view all the answers

What is the effect of curare-like drugs during surgical procedures?

<p>Facilitates intubation and muscle relaxation (D)</p> Signup and view all the answers

What is the primary pathophysiological mechanism in Myasthenia Gravis (MG)?

<p>Autoimmune attack on acetylcholine receptors (B)</p> Signup and view all the answers

What is the main effect of Botulinum Toxin on neuromuscular transmission?

<p>Inhibition of acetylcholine release (D)</p> Signup and view all the answers

What is the consequence of reduced effective density of acetylcholine receptors in MG?

<p>Impaired signal transmission and muscle weakness (A)</p> Signup and view all the answers

Which muscles are particularly affected in Myasthenia Gravis?

<p>Muscles controlling eye and facial movements, chewing, and swallowing (B)</p> Signup and view all the answers

What is the source of Botulinum Toxin?

<p>Clostridium botulinum bacteria (D)</p> Signup and view all the answers

How does Botulinum Toxin cause muscle paralysis?

<p>Blocking of acetylcholine receptors (A)</p> Signup and view all the answers

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