Podcast
Questions and Answers
Which of the following is the primary target of the autoimmune response in myasthenia gravis?
Which of the following is the primary target of the autoimmune response in myasthenia gravis?
A patient with myasthenia gravis is experiencing increased weakness in their intercostal muscles. This can most directly lead to which of the following?
A patient with myasthenia gravis is experiencing increased weakness in their intercostal muscles. This can most directly lead to which of the following?
What is the typical initial presentation of symptoms in a patient with myasthenia gravis?
What is the typical initial presentation of symptoms in a patient with myasthenia gravis?
Which diagnostic test is commonly used to assess a patient with suspected Myasthenia Gravis?
Which diagnostic test is commonly used to assess a patient with suspected Myasthenia Gravis?
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Which of the following is a key difference between myasthenia gravis and multiple sclerosis?
Which of the following is a key difference between myasthenia gravis and multiple sclerosis?
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Which of the following best describes the primary characteristic of meningitis?
Which of the following best describes the primary characteristic of meningitis?
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What are the two main classifications of meningitis based on etiology?
What are the two main classifications of meningitis based on etiology?
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Aseptic meningitis is most often caused by:
Aseptic meningitis is most often caused by:
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Which pathogen is commonly associated with meningitis outbreaks in communal living settings, such as college campuses?
Which pathogen is commonly associated with meningitis outbreaks in communal living settings, such as college campuses?
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Besides headache and fever, which combination of signs and symptoms is most indicative of meningitis?
Besides headache and fever, which combination of signs and symptoms is most indicative of meningitis?
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What clinical finding is associated with the Kernig sign?
What clinical finding is associated with the Kernig sign?
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A patient with suspected meningitis presents with severe headache and stiff neck. During the assessment, when the patient's neck is flexed forward, they react by flexing their knees and hips. Which sign is this indicative of?
A patient with suspected meningitis presents with severe headache and stiff neck. During the assessment, when the patient's neck is flexed forward, they react by flexing their knees and hips. Which sign is this indicative of?
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Which of the following is NOT a typical manifestation of meningitis?
Which of the following is NOT a typical manifestation of meningitis?
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Which of the following describes the Kernig sign?
Which of the following describes the Kernig sign?
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What is the primary rationale for administering dexamethasone in the treatment of bacterial meningitis?
What is the primary rationale for administering dexamethasone in the treatment of bacterial meningitis?
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Which intervention is crucial for preventing complications associated with immobility in a patient with meningitis?
Which intervention is crucial for preventing complications associated with immobility in a patient with meningitis?
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A patient with a brain abscess is exhibiting signs of increased intracranial pressure (ICP). Which of the following symptoms would you expect the patient to display?
A patient with a brain abscess is exhibiting signs of increased intracranial pressure (ICP). Which of the following symptoms would you expect the patient to display?
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What is the main diagnostic procedure for identifying the causative organisms of a brain abscess?
What is the main diagnostic procedure for identifying the causative organisms of a brain abscess?
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What is the primary nursing intervention when caring for a patient with encephalitis who is experiencing an altered level of consciousness?
What is the primary nursing intervention when caring for a patient with encephalitis who is experiencing an altered level of consciousness?
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A patient is diagnosed with meningitis. Which of the following lab results would the nurse prioritize for review?
A patient is diagnosed with meningitis. Which of the following lab results would the nurse prioritize for review?
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In addition to antibiotics, what other medication class might be prescribed when managing a brain abscess to address cerebral edema?
In addition to antibiotics, what other medication class might be prescribed when managing a brain abscess to address cerebral edema?
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Which of the following describes the Brudzinski sign?
Which of the following describes the Brudzinski sign?
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A patient with meningitis is experiencing photophobia. What nursing intervention would be most appropriate to manage this symptom?
A patient with meningitis is experiencing photophobia. What nursing intervention would be most appropriate to manage this symptom?
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What is the main goal of medical management for Myasthenia Gravis?
What is the main goal of medical management for Myasthenia Gravis?
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Which of the following medications are NOT typically used in the treatment of Myasthenia Gravis?
Which of the following medications are NOT typically used in the treatment of Myasthenia Gravis?
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What is the most common cause of a Myasthenic Crisis?
What is the most common cause of a Myasthenic Crisis?
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Which of the following symptoms is characteristic of both Myasthenic Crisis and Cholinergic Crisis?
Which of the following symptoms is characteristic of both Myasthenic Crisis and Cholinergic Crisis?
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What is the primary cause of a Cholinergic Crisis?
What is the primary cause of a Cholinergic Crisis?
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Which of the following measures is NOT recommended in the management of Myasthenic and Cholinergic Crisis?
Which of the following measures is NOT recommended in the management of Myasthenic and Cholinergic Crisis?
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What is the purpose of chest physiotherapy in the management of Myasthenic and Cholinergic Crisis?
What is the purpose of chest physiotherapy in the management of Myasthenic and Cholinergic Crisis?
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What is the primary focus of patient education regarding Myasthenic and Cholinergic Crisis?
What is the primary focus of patient education regarding Myasthenic and Cholinergic Crisis?
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What is the primary reason patients with trigeminal neuralgia might isolate themselves?
What is the primary reason patients with trigeminal neuralgia might isolate themselves?
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Which branch of the trigeminal nerve is most commonly involved in trigeminal neuralgia?
Which branch of the trigeminal nerve is most commonly involved in trigeminal neuralgia?
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What is a potential side effect of carbamazepine, an anticonvulsant used for trigeminal neuralgia?
What is a potential side effect of carbamazepine, an anticonvulsant used for trigeminal neuralgia?
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What is the most common age range for the onset of Bell's Palsy?
What is the most common age range for the onset of Bell's Palsy?
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What intervention can help in the recovery from Bell’s Palsy?
What intervention can help in the recovery from Bell’s Palsy?
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What is the purpose of corticosteroid therapy in the management of Bell's Palsy?
What is the purpose of corticosteroid therapy in the management of Bell's Palsy?
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Which of the following is NOT a nursing intervention for trigeminal neuralgia?
Which of the following is NOT a nursing intervention for trigeminal neuralgia?
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What symptom includes unilateral facial muscle weakness and distortion?
What symptom includes unilateral facial muscle weakness and distortion?
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What is a common aggravating factor for trigeminal neuralgia pain?
What is a common aggravating factor for trigeminal neuralgia pain?
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Which medical treatment is considered an adjunctive therapy for trigeminal neuralgia?
Which medical treatment is considered an adjunctive therapy for trigeminal neuralgia?
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What is the most common initial symptom of Guillain–Barré Syndrome?
What is the most common initial symptom of Guillain–Barré Syndrome?
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What is a significant risk associated with the rapid progression of Guillain–Barré Syndrome?
What is a significant risk associated with the rapid progression of Guillain–Barré Syndrome?
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Which of the following is NOT a clinical manifestation of Guillain–Barré Syndrome?
Which of the following is NOT a clinical manifestation of Guillain–Barré Syndrome?
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What is the goal of therapeutic plasma exchange in Guillain–Barré Syndrome?
What is the goal of therapeutic plasma exchange in Guillain–Barré Syndrome?
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When planning care for a patient with Multiple Sclerosis, which goal is least likely to be prioritized?
When planning care for a patient with Multiple Sclerosis, which goal is least likely to be prioritized?
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In the context of Multiple Sclerosis, what age range is associated with the peak onset of the disease?
In the context of Multiple Sclerosis, what age range is associated with the peak onset of the disease?
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Which of the following therapies is commonly used in the medical management of Multiple Sclerosis?
Which of the following therapies is commonly used in the medical management of Multiple Sclerosis?
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Which assessment parameter is crucial for early detection of complications in Guillain–Barré Syndrome?
Which assessment parameter is crucial for early detection of complications in Guillain–Barré Syndrome?
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Which nursing intervention is recommended for enhancing mobility in patients with Guillain–Barré Syndrome?
Which nursing intervention is recommended for enhancing mobility in patients with Guillain–Barré Syndrome?
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What lifestyle factor is associated with a higher prevalence of Multiple Sclerosis?
What lifestyle factor is associated with a higher prevalence of Multiple Sclerosis?
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Which cranial nerve disorder is characterized by unilateral pain described as shooting or stabbing?
Which cranial nerve disorder is characterized by unilateral pain described as shooting or stabbing?
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In the management of Multiple Sclerosis, which of the following is a recommended intervention to minimize stress?
In the management of Multiple Sclerosis, which of the following is a recommended intervention to minimize stress?
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Which of the following interventions is crucial in the prevention of deep vein thrombosis (DVT) for Guillain–Barré Syndrome patients?
Which of the following interventions is crucial in the prevention of deep vein thrombosis (DVT) for Guillain–Barré Syndrome patients?
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Which symptom is commonly associated with autonomic dysfunction in Guillain–Barré Syndrome?
Which symptom is commonly associated with autonomic dysfunction in Guillain–Barré Syndrome?
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Flashcards
Meningitis
Meningitis
Inflammation of the meninges, the protective membranes surrounding the brain and spinal cord.
Septic Meningitis
Septic Meningitis
A type of meningitis caused by bacteria like Streptococcus pneumoniae or Neisseria meningitidis.
Aseptic Meningitis
Aseptic Meningitis
A type of meningitis caused by a viral infection, often secondary to a weakened immune system or cancer.
Nuchal Rigidity
Nuchal Rigidity
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Kernig Sign
Kernig Sign
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Brudzinski Sign
Brudzinski Sign
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Subarachnoid Space
Subarachnoid Space
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Pia Mater
Pia Mater
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Myasthenia Gravis
Myasthenia Gravis
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Ocular Myasthenia Gravis
Ocular Myasthenia Gravis
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Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
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Myasthenic Crisis
Myasthenic Crisis
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Acetylcholinesterase Inhibitor Test
Acetylcholinesterase Inhibitor Test
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Brain Abscess
Brain Abscess
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Encephalitis
Encephalitis
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Increased ICP
Increased ICP
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Fluid and Volume Expanders
Fluid and Volume Expanders
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Dexamethasone
Dexamethasone
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Antibiotics for Bacterial Meningitis
Antibiotics for Bacterial Meningitis
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Anticonvulsants
Anticonvulsants
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What is a myasthenic crisis?
What is a myasthenic crisis?
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What is a cholinergic crisis?
What is a cholinergic crisis?
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How is ventilation managed in myasthenic and cholinergic crises?
How is ventilation managed in myasthenic and cholinergic crises?
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What are the important assessments for myasthenic and cholinergic crises?
What are the important assessments for myasthenic and cholinergic crises?
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Why do you need to avoid sedatives and tranquilizers in myasthenic and cholinergic crises?
Why do you need to avoid sedatives and tranquilizers in myasthenic and cholinergic crises?
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What is a thymectomy?
What is a thymectomy?
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What is intravenous immune globulin (IVIG)?
What is intravenous immune globulin (IVIG)?
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What is therapeutic plasma exchange?
What is therapeutic plasma exchange?
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Trigeminal Neuralgia
Trigeminal Neuralgia
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Second and Third Branches of the Trigeminal Nerve
Second and Third Branches of the Trigeminal Nerve
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Vascular Compression
Vascular Compression
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Fifth and Sixth Decades
Fifth and Sixth Decades
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Stimulation
Stimulation
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Carbamazepine
Carbamazepine
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Microvascular Decompression
Microvascular Decompression
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Bell's Palsy
Bell's Palsy
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Unilateral Facial Muscle Weakness
Unilateral Facial Muscle Weakness
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Corticosteroid Therapy
Corticosteroid Therapy
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What is Guillain-Barré Syndrome?
What is Guillain-Barré Syndrome?
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What is Multiple Sclerosis (MS)?
What is Multiple Sclerosis (MS)?
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What is the typical time frame for Guillain-Barré Syndrome symptoms?
What is the typical time frame for Guillain-Barré Syndrome symptoms?
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What are the key clinical manifestations of Guillain-Barré Syndrome?
What are the key clinical manifestations of Guillain-Barré Syndrome?
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How is Guillain-Barré Syndrome medically managed?
How is Guillain-Barré Syndrome medically managed?
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What are the primary treatments for Guillain-Barré Syndrome?
What are the primary treatments for Guillain-Barré Syndrome?
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What are the key aspects of ongoing assessment for Guillain-Barré Syndrome patients?
What are the key aspects of ongoing assessment for Guillain-Barré Syndrome patients?
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What are the primary collaborative problems and potential complications in Guillain-Barré Syndrome?
What are the primary collaborative problems and potential complications in Guillain-Barré Syndrome?
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What are the major goals of nursing care for Guillain-Barré Syndrome patients?
What are the major goals of nursing care for Guillain-Barré Syndrome patients?
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What are some key nursing interventions for Guillain-Barré Syndrome patients?
What are some key nursing interventions for Guillain-Barré Syndrome patients?
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How can nurses help reduce fear and anxiety in Guillain-Barré Syndrome patients?
How can nurses help reduce fear and anxiety in Guillain-Barré Syndrome patients?
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What are some common disease-modifying therapies for Multiple Sclerosis?
What are some common disease-modifying therapies for Multiple Sclerosis?
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How are symptoms effectively managed in Multiple Sclerosis?
How are symptoms effectively managed in Multiple Sclerosis?
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What are the essential aspects of nursing care for Multiple Sclerosis patients?
What are the essential aspects of nursing care for Multiple Sclerosis patients?
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What are some key nursing interventions for Multiple Sclerosis patients?
What are some key nursing interventions for Multiple Sclerosis patients?
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Study Notes
Chapter 64: Management of Patients with Neurologic Infections, Autoimmune Disorders, and Neuropathies
- This chapter focuses on the management of patients with neurologic infections, autoimmune disorders, and neuropathies.
- Learning objectives include differentiating infectious nervous system disorders, describing the pathophysiology and management of multiple sclerosis, myasthenia gravis, and Guillain-Barré syndrome, utilizing the nursing process for patient care, explaining cranial nerve disorders and their management, and applying the nursing process to cranial nerve disorders.
Infectious Neurologic Disorders
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Meningitis: Inflammation of the meninges (membranes surrounding the brain and spinal cord). Two main types: bacterial and viral. Bacterial meningitis is often caused by Streptococcus pneumoniae or Neisseria meningitidis. Aseptic meningitis is caused by viral infection. Symptoms include headache, fever, changes in LOC, stiff neck, positive Kernig and Brudzinski signs, and photophobia.
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Brain Abscesses: Collections of infectious material within brain tissue. Most commonly caused by bacteria. Symptoms include headache (often worse in the morning), fever, vomiting, neurological deficits, and signs of increased intracranial pressure (ICP). ICP increases as the abscess expands, leading to decreased LOC and seizures. Diagnosis is done using MRI or CT scans, and CT-guided aspiration is used to identify the causative organisms.
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Encephalitis: An acute, inflammatory process of the brain tissue. Caused by viral infections (e.g., herpes simplex virus [HSV], West Nile virus, St. Louis encephalitis virus) or fungal infections. Symptoms include headache, fever, confusion, hallucinations, rash, flaccid paralysis, and Parkinson's-like movements.
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Creutzfeldt-Jakob Disease (CJD) and Variant CJD (vCJD): Rare, degenerative, transmissible spongiform encephalopathies (TSEs). Caused by prions (small proteinaceous particles). Not spread by casual contact. vCJD may be contracted through ingestion of infected beef. Symptoms include cognitive impairments, sensory and motor problems, behavioral changes, and sleep disturbances. There is no effective treatment. The disease is progressive and fatal, typically within one year.
Meningitis: Medical Management
- Prevention by meningococcal vaccine.
- Early administration of high doses of appropriate intravenous (IV) antibiotics for bacterial meningitis.
- Dexamethasone (review dosing).
- Close contacts with patients should receive chemoprophylaxis using rifampin, ciprofloxacin, or ceftriaxone.
- Treatment for dehydration and shock (fluid and volume expanders).
- Monitoring for signs of increasing intracranial pressure (ICP).
- Monitoring for decreased level of consciousness (LOC) and focal motor deficits.
- Monitoring for signs of sepsis.
- Recognizing signs like an abrupt onset of high fever, shock, disseminated intravascular coagulation (DIC), and purpura.
Meningitis: Nursing Management
- Collaborate with the care team for critically ill patients.
- Frequent neurological assessment, including vital signs and level of consciousness.
- Pain and fever management.
- Protect the patient from injury related to seizure activity or altered LOC.
- Monitor daily weight, electrolytes, urine volume, specific gravity, and osmolality.
- Prevent complications associated with immobility.
- Review laboratory tests.
- Providing supportive care in a quiet, controlled, darkened room.
- Facilitate coping for the patient and family.
Brain Abscess: Medical and Nursing Management
- Medical management is focused on controlling increased ICP and draining the abscess.
- Appropriate antibiotic therapy, initiated as soon as possible based on culture and sensitivity, is crucial.
- Corticosteroids may be used to treat cerebral edema, and anticonvulsants might be necessary to control seizures.
- Nursing management includes frequent and ongoing neurological assessments, administering medications, assessing the patient's response to treatment, and providing supportive care.
Encephalitis: Medical Management
- Acyclovir for HSV infection.
- Antifungal agents for fungal infection (up to 3 weeks).
- Frequent and ongoing neurological assessments.
- Dim lighting, limited visitors, and clustering of care.
- Analgesics and cautious opioid use.
- Monitoring of kidney function with antiviral use.
- Supportive care.
Creutzfeldt-Jakob Disease: Medical Management
- Prevention of disease transmission via blood and body fluid precautions.
- Use of disposable medical instruments whenever possible.
- Supportive and palliative care.
- Psychological support.
Autoimmune Nervous System Disorders
- This section covers multiple sclerosis (MS), myasthenia gravis, and Guillain-Barré syndrome.
Multiple Sclerosis (MS):
- An immune-mediated, progressive demyelinating disease in the central nervous system.
- Clinical manifestations vary.
- Four main clinical forms.
- Higher prevalence in northern, colder latitudes.
- Onset usually between 20 and 50 years of age. Affects women more than men.
- Commonly relapsing and remitting, with exacerbations and recurrences of symptoms, including fatigue, weakness, numbness, balance problems, pain, and visual disturbances.
Myasthenia Gravis:
- An autoimmune disorder affecting the myoneural junction.
- Characterized by varying degrees of weakness of voluntary muscles.
- Antibodies impair acetylcholine transmission at the myoneural junctions.
- Two clinical forms: ocular and generalized. Initial symptoms often involve the ocular muscles (diplopia, ptosis).
- Generalized weakness can affect facial muscles, swallowing, voice, and all extremities, potentially progressing to intercostal muscles and respiratory failure (myasthenic crisis).
- Diagnostic tests include acetylcholinesterase inhibitor testing (with atropine on hand to prevent side effects), and ice tests for those with cardiac or asthma issues.
Guillain-Barré Syndrome:
- An autoimmune disorder causing an acute attack on peripheral nerve myelin.
- Rapid demyelination can lead to respiratory failure and autonomic dysfunction (e.g., CV instability).
- Often triggered by a viral infection (1-3 weeks prior).
- Maximum weakness peaks within 2-4 weeks.
- Variable manifestations include weakness or paralysis that starts in the lower extremities and ascends symmetrically, bulbar weakness, cranial nerve symptoms, tachycardia, bradycardia, hypertension, or hypotension.
- Includes supportive treatment (plasma exchange, immunoglobulin or IVIG). Recovery rates vary, but most patients improve fully.
Cranial Nerve Disorders
- This section discusses specific cranial nerve disorders like trigeminal neuralgia (tic douloureux), Bell's palsy
Trigeminal Neuralgia:
- Condition of the fifth cranial nerve, characterized by brief, sudden attacks of severe pain.
- Pain may be unilateral and is described as shooting, stabbing, or burning.
- Most commonly affects the second and third branches of the trigeminal nerve.
- Vascular compression is often a cause.
- Common in the fifth and sixth decades of life, and may occur in people with multiple sclerosis.
- Patients may avoid stimulation (e.g., eating, washing face).
Bell's Palsy:
- Unilateral inflammation of the seventh cranial nerve causing facial paralysis.
- Symptoms include unilateral facial muscle weakness or paralysis, facial distortion, increased lacrimation, and possibly pain in the facial area.
- Most patients recover completely in 3 to 5 weeks.
- Treatment focuses on maintaining muscle tone and preventing denervation.
Medical and Nursing Interventions
- Summaries of medical and nursing interventions for each disorder are presented throughout the notes. These interventions are specific for each condition and may include medications, supportive care, prevention of complications, managing symptoms, patient education, and emotional support. There is a particular focus on recognizing and addressing signs of impending complications (e.g., increased ICP in meningitis) from the outset.
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Description
Test your knowledge on myasthenia gravis and meningitis with this quiz. Explore key symptoms, diagnostic tests, and pathogen associations. Perfect for medical students and professionals looking to reinforce their understanding of these conditions.