L1 Muscle Physiology: Membrane and Action Potentials
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Questions and Answers

What type of potential exactly balances the tendency of an ion to diffuse down its concentration gradient?

  • Membrane potential
  • Resting potential
  • Nernst potential (correct)
  • Equilibrium potential

What is the driving force behind the movement of uncharged molecules across a membrane?

  • Osmotic pressure
  • Hydrostatic pressure
  • Concentration gradient (correct)
  • Electrical charges

What is the typical value of the equilibrium potential for potassium ions (EK+)?

  • +65 mV
  • -90 mV
  • +120 mV
  • -85 mV (correct)

What is the primary factor that determines the diffusion potential across a membrane?

<p>Concentration gradient (C)</p> Signup and view all the answers

What would happen if the membrane was not permeable to the ion in question?

<p>No diffusion potential would be generated (A)</p> Signup and view all the answers

What type of cells undergo controlled changes in their membrane potential?

<p>Neurons and muscle cells (C)</p> Signup and view all the answers

What is the term for the difference in electric potential between the interior and exterior of a biological cell?

<p>Membrane potential (B)</p> Signup and view all the answers

What is the effect of a diffusion potential on the concentration of ions in bulk solution?

<p>It has no effect on the concentration of ions (C)</p> Signup and view all the answers

What is the typical value of the equilibrium potential for sodium ions (ENa+)?

<p>+65 mV (B)</p> Signup and view all the answers

What is the diffusion potential generated by?

<p>The movement of a charged solute down its concentration gradient (C)</p> Signup and view all the answers

What is the relationship between the diffusion potential and the concentration gradient?

<p>The diffusion potential is directly proportional to the concentration gradient (C)</p> Signup and view all the answers

What is the term for the membrane potential of a cell that remains relatively constant over time?

<p>Resting potential (C)</p> Signup and view all the answers

What is the resting potential of nerve fibers when not transmitting nerve signals?

<p>-70 millivolts (D)</p> Signup and view all the answers

What is the main contributor to the resting potential of nerve cells?

<p>Potassium diffusion (B)</p> Signup and view all the answers

What is the selectivity of the potassium leak channels?

<p>100x higher for K than for Na ions (B)</p> Signup and view all the answers

Why do potassium ions move into the cell?

<p>Attracted to negative charges (A)</p> Signup and view all the answers

What is the role of the Na-K pump?

<p>To maintain the resting potential of nerve cells (D)</p> Signup and view all the answers

Why is the membrane less permeable to sodium ions?

<p>The membrane is more permeable to potassium ions (B)</p> Signup and view all the answers

What is the minimal membrane potential required to trigger an action potential?

<p>-55 mV (A)</p> Signup and view all the answers

What happens to the membrane potential during depolarization?

<p>It rises in the positive direction (B)</p> Signup and view all the answers

What causes the rapid diffusion of K ions out of the cell during repolarization?

<p>Voltage-gated potassium channels (B)</p> Signup and view all the answers

What is the term for the state when neurons have a more negative membrane potential than normal?

<p>Hyperpolarization (B)</p> Signup and view all the answers

What is the absolute refractory period?

<p>The time needed for the voltage-gated sodium channels to revert from the inactivated state to the resting closed state (A)</p> Signup and view all the answers

What is the relative refractory period?

<p>The time when the membrane is in a hyperpolarization state (A)</p> Signup and view all the answers

What is the primary function of the Na-K pump?

<p>To transport Na+ out and K+ in (C)</p> Signup and view all the answers

What is the role of the ATPase function in the Na-K pump?

<p>To activate the pump after binding of Na+ and K+ ions (A)</p> Signup and view all the answers

What is the significance of the resting potential in neurons?

<p>It is necessary for the transmission of nerve signals (D)</p> Signup and view all the answers

What is the characteristics of an action potential?

<p>A rapid change in the membrane potential that spreads rapidly along the nerve fiber (A)</p> Signup and view all the answers

What are the five stages of an action potential?

<p>Resting, threshold, depolarization, repolarization, and hyperpolarization (A)</p> Signup and view all the answers

What is the significance of the Na-K pump in controlling the volume of a cell?

<p>It helps to remove excess sodium ions from the cell (A)</p> Signup and view all the answers

What is the primary driving force behind the movement of charged molecules across a membrane?

<p>Electrical charges (C)</p> Signup and view all the answers

What is necessary for a diffusion potential to be generated across a membrane?

<p>A concentration gradient of charged molecules and membrane permeability (A)</p> Signup and view all the answers

What is the effect of a diffusion potential on the bulk solution?

<p>No effect on the concentration of ions (D)</p> Signup and view all the answers

What determines the magnitude of the diffusion potential across a membrane?

<p>Both the concentration gradient and permeability of the membrane (B)</p> Signup and view all the answers

What would happen if a membrane was not permeable to the ion in question?

<p>No diffusion potential would be generated (B)</p> Signup and view all the answers

What is the relationship between the diffusion potential and the concentration gradient?

<p>The diffusion potential increases with an increase in concentration gradient (B)</p> Signup and view all the answers

What is the main factor that determines the equilibrium potential of an ion?

<p>Both the electrical charge and concentration inside and outside the membrane (B)</p> Signup and view all the answers

What is the characteristic of the membrane potential in most animal cells?

<p>It does not vary with time (B)</p> Signup and view all the answers

What is the term for the membrane potential that remains relatively constant over time?

<p>Resting potential (A)</p> Signup and view all the answers

What is the primary factor that determines the membrane potential of a cell?

<p>The relative permeability of each ion (D)</p> Signup and view all the answers

What is the difference between the electric potential inside and outside a biological cell?

<p>Membrane potential (D)</p> Signup and view all the answers

Which type of cells do not undergo controlled changes in their membrane potential?

<p>Most animal cells (A)</p> Signup and view all the answers

What is the primary contributor to the resting potential of nerve cells?

<p>Diffusion of potassium through the nerve cell membrane (C)</p> Signup and view all the answers

What determines the selectivity of potassium leak channels?

<p>The protein structure of the channel (D)</p> Signup and view all the answers

What is the direction of potassium ion movement in the resting state?

<p>Out of the cell (B)</p> Signup and view all the answers

What is the effect of the Na-K pump on the resting potential?

<p>It maintains the resting potential (C)</p> Signup and view all the answers

Why are potassium ions attracted to the inside of the cell?

<p>Because of the negative charges inside the cell (B)</p> Signup and view all the answers

What is the typical value of the resting potential of nerve fibers when not transmitting nerve signals?

<p>-70 millivolts (D)</p> Signup and view all the answers

What is the primary function of the Na-K pump in neurons?

<p>To control the volume of the cell and maintain the resting potential (A)</p> Signup and view all the answers

What is the characteristic of the action potential that allows it to spread rapidly along the nerve fiber membrane?

<p>The sudden change from the resting negative membrane potential to a positive potential (D)</p> Signup and view all the answers

What is the consequence of the dynamic changes in the membrane potential in neurons and muscle cells?

<p>The generation of action potentials (D)</p> Signup and view all the answers

What is the role of the ATPase function in the Na-K pump?

<p>To activate the pump after binding of sodium and potassium ions (B)</p> Signup and view all the answers

What is the significance of the resting potential in nerve cells?

<p>It is essential for the transmission of nerve signals (A)</p> Signup and view all the answers

How many stages are involved in the action potential?

<p>5 stages (D)</p> Signup and view all the answers

What is the minimum membrane potential required to initiate an action potential?

<p>-55 mV (A)</p> Signup and view all the answers

What type of channels are activated during depolarization?

<p>Voltage-gated sodium channels (B)</p> Signup and view all the answers

What is the term for the state when neurons have a more negative membrane potential than normal after an action potential?

<p>Hyperpolarization (A)</p> Signup and view all the answers

What is the primary function of the voltage-gated potassium channels during an action potential?

<p>To slow down the depolarization process (C)</p> Signup and view all the answers

What is the period during which the voltage-gated sodium channels are closed and cannot be reopened?

<p>Absolute refractory period (D)</p> Signup and view all the answers

What is the stage of the action potential during which the membrane potential becomes highly permeable to sodium ions?

<p>Depolarization (D)</p> Signup and view all the answers

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