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13 Questions

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W3-Contractile Cells

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Questions and Answers

What causes transmitter release?

Neuronal action potential

Nicotinic AchR activation

Acetylcholine release

Synaptic vesicle (correct)

What does a rise in calcium do?

Causes membrane depolarization

Promotes actin-myosin interaction and cell shortening (correct)

Triggers acetylcholine release

Activates voltage-sensitive DHP protein

What is the main difference between skeletal and smooth muscle contraction?

Smooth muscle uses troponin-tropomyosin complex, while skeletal muscle does not

Smooth muscle has motor nerve activation, while skeletal muscle does not

Skeletal muscle contracts more slowly than smooth muscle

Skeletal muscle has striations, while smooth muscle does not (correct)

What leads to a rise in calcium during skeletal muscle activation?

Opening of voltage-sensitive calcium channels Signup and view all the answers

What is the primary event following acetylcholine release at the neuromuscular junction?

Activation of nicotinic AchR Signup and view all the answers

What is the role of SERCA in skeletal muscle contraction?

Pumping calcium ions out of the cytoplasm into the sarcoplasmic reticulum Signup and view all the answers

What triggers calcium-induced calcium release (CICR) in cardiac muscle contraction?

Membrane depolarization through T-tubules Signup and view all the answers

What is the function of Troponin-T?

Binds to tropomyosin Signup and view all the answers

How does calcium influx affect smooth muscle contraction?

Activates Myosin Light Chain Kinase (MLCK) Signup and view all the answers

What differentiates the myosin isoform in smooth muscle from that in skeletal muscle?

Lower ATPase activity Signup and view all the answers

What is the role of Myosin Light Chain Kinase (MLCK) in smooth muscle cells?

Activates myosin light chains by phosphorylation Signup and view all the answers

What is the function of Troponin-C?

Calcium binding Signup and view all the answers

What initiates the depolarization process in a skeletal muscle cell?

Neuronal Action Potential (AP) Signup and view all the answers