Podcast
Questions and Answers
Which molecule is involved in down-regulating T cell activation by binding to B7.1/2 with higher affinity than CD28?
Which molecule is involved in down-regulating T cell activation by binding to B7.1/2 with higher affinity than CD28?
- TGF-b
- CTLA-4 (correct)
- PD-1
- IL-10
What is the function of CTLA-4 in activated T cells?
What is the function of CTLA-4 in activated T cells?
- Promote cell growth
- Enhance IL-2 production
- Activate APCs
- Inhibit proliferation (correct)
Do effector T cells require costimulatory signals?
Do effector T cells require costimulatory signals?
- Effector T cells require costimulatory signals only in the presence of APCs
- Yes, they always require costimulatory signals
- Effector T cells sometimes require costimulatory signals
- No, they never require costimulatory signals (correct)
Which pathway of cell death is triggered by the Fas-FasL pathway involving CTLs?
Which pathway of cell death is triggered by the Fas-FasL pathway involving CTLs?
Which type of Tregs arise in the periphery from CD4+ T cells?
Which type of Tregs arise in the periphery from CD4+ T cells?
What is the role of ILC2 and TH2 cells in infections?
What is the role of ILC2 and TH2 cells in infections?
Which molecule is expressed on activated T cells and down-regulates T cell activation?
Which molecule is expressed on activated T cells and down-regulates T cell activation?
What function do Treg cells serve in immune responses?
What function do Treg cells serve in immune responses?
What is the main function of Treg cells?
What is the main function of Treg cells?
When does clonal contraction occur in the immune response?
When does clonal contraction occur in the immune response?
Which molecule binds PDL-1 and PDL-2 to down-regulate T cell activation?
Which molecule binds PDL-1 and PDL-2 to down-regulate T cell activation?
Which cytokines are produced by ILC3 cells to defend against bacterial infection?
Which cytokines are produced by ILC3 cells to defend against bacterial infection?
What is the main function of IL-10 and TGF-b in the context of immune responses?
What is the main function of IL-10 and TGF-b in the context of immune responses?
What happens to most lymphocytes after an antigen is removed?
What happens to most lymphocytes after an antigen is removed?
What happens to B7 molecules when CTLA-4 binds to them?
What happens to B7 molecules when CTLA-4 binds to them?
Which type of infection do ILC2 and TH2 cells assist in clearing?
Which type of infection do ILC2 and TH2 cells assist in clearing?
What contributes to the activation of ILCs?
What contributes to the activation of ILCs?
What do effector T cells do once they have been activated, proliferated, and differentiated?
What do effector T cells do once they have been activated, proliferated, and differentiated?
What happens to newly generated B and T cells at the end of the primary immune response?
What happens to newly generated B and T cells at the end of the primary immune response?
