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Questions and Answers
What is the main mechanism for transporting maternal antibodies to fetus/newborns?
What is the main mechanism for transporting maternal antibodies to fetus/newborns?
- IgA specific Fc receptor in fetal gut epithelium
- TGF-b in maternal circulation
- Neonatal Fc receptor (FcRn) in placenta (correct)
- Poly-Ig receptor in fetal intestines
What is the key regulator for isotype switching to IgA?
What is the key regulator for isotype switching to IgA?
- TGF-b (correct)
- IgM
- IgA specific Fc receptor
- Tumor suppressor
What percentage of daily Ig production is IgA in the intestines?
What percentage of daily Ig production is IgA in the intestines?
- 30-40%
- 60-70% (correct)
- 10-20%
- 80-90%
What is the role of TGFβ in tumorigenesis?
What is the role of TGFβ in tumorigenesis?
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How do microbes evade detection by antibodies?
How do microbes evade detection by antibodies?
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