Mucosal Immunity and IgA Antibodies
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Questions and Answers

What is the main mechanism for transporting maternal antibodies to fetus/newborns?

  • IgA specific Fc receptor in fetal gut epithelium
  • TGF-b in maternal circulation
  • Neonatal Fc receptor (FcRn) in placenta (correct)
  • Poly-Ig receptor in fetal intestines

    • What is the key regulator for isotype switching to IgA?

  • TGF-b (correct)
  • IgM
  • IgA specific Fc receptor
  • Tumor suppressor

    • What percentage of daily Ig production is IgA in the intestines?

  • 30-40%
  • 60-70% (correct)
  • 10-20%
  • 80-90%

    • What is the role of TGFβ in tumorigenesis?

    <p>Inhibits cell cycle promotion</p> Signup and view all the answers

    How do microbes evade detection by antibodies?

    <p>Undergo mutations</p> Signup and view all the answers

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