Immunology MCQs on Lymphoid Organs and Antibodies

Immunology Multiple Choice Questions (MCQs)

• Primary Lymphoid Organs: The thymus is a primary lymphoid organ.
• Complement Activation and Antibodies: IgM is the most effective antibody isotype for activating the classical complement pathway.
• MHC Class I Function: MHC Class I molecules present intracellular antigens to CD8+ T cells.
• Affinity Maturation Location: Affinity maturation occurs in the germinal centers of lymph nodes.
• Antibody Production: Plasma cells are the primary producers of antibodies.
• Alternative Pathway Complement Protein: C3 is the first complement protein activated in the alternative pathway.
• Membrane Attack Complex (MAC): MAC creates pores in pathogen membranes.
• TH1 Response Macrophage Activation: IFN-γ is critical for activating macrophages in a TH1 response.
• Chronic Inflammation Characteristic: Granuloma formation characterizes chronic inflammation.
• Type I Hypersensitivity Mechanism: IgE and mast cells are involved in Type I hypersensitivity.
• V(D)J Recombination Enzyme: Recombinase (RAG1/2) is responsible for V(D)J recombination in B and T cells.
• Secondary Lymphoid Organ: The spleen is a secondary lymphoid organ.
• Dendritic Cell Function: Dendritic cells present antigens to T cells.
• Classical Complement Pathway Regulation: C1 inhibitor (C1-INH) regulates the classical complement pathway.
• TH2 Cells and Immune Response: TH2 cells are involved in allergy and parasitic infections.
• CD8+ T Cell Recognition: CD8+ T cells recognize MHC Class I on target cells.
• Type III Hypersensitivity: Immune complexes mediate Type III hypersensitivity.
• Hygiene Hypothesis and Disease: Reduced exposure to pathogens can increase autoimmune and allergic diseases according to the hygiene hypothesis.
• Alternative Pathway C3b Stabilization: Properdin stabilizes C3b on pathogen surfaces in the alternative pathway.
• Histamine Production in Inflammation: Mast cells produce histamine during inflammation.
• T Regulatory (TREG) Cell Function: TREG cells suppress immune responses.
• Membrane Attack Complex (MAC) Target: The target of the MAC is the lipid bilayers of pathogens.
• TH17 Cell Differentiation: IL-23 drives the differentiation of TH17 cells.
• Adaptive Immunity Feature: Immunological memory is a key feature of adaptive immunity.
• Complement Pathway Requiring Antibodies: The classical pathway requires antibodies.
• Acute Phase Proteins: Acute phase proteins enhance phagocytosis and inflammation.
• First Immune Cell in Acute Inflammation: Neutrophils are the first immune cells to arrive during acute inflammation.
• IL-2 Function: IL-2 promotes T cell proliferation.
• MHC Class II Antigen Processing: MHC Class II antigen processing involves lysosomal degradation of extracellular antigens.
• Rheumatoid Arthritis Lab Marker: Rheumatoid factor (RF) is associated with Rheumatoid Arthritis.

Test your knowledge with these multiple-choice questions on immunology. This quiz covers essential topics such as primary lymphoid organs, antibody production, complement activation, and the TH1 immune response. Ideal for students studying immunology and related disciplines.