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Questions and Answers

Which of the following is a semisynthetic derivative of beta-lactams?

  • Methicillin (correct)
  • Bacitracin
  • Penicillin G
  • Isoniazid
  • What defines a broad-spectrum antimicrobial agent?

  • Effective against many organisms with an unknown specific agent. (correct)
  • Agent is known and identified.
  • Effective against a limited range of organisms.
  • Used specifically for viral infections.
  • What is the primary action of Tetracyclines in microbial treatment?

  • Disrupting mycolic acid biosynthesis.
  • Blocking the transport of NAG and NAM.
  • Interfering with protein synthesis by blocking tRNA docking sites. (correct)
  • Attaching to ergosterol in fungal membranes.
  • What is the purpose of the therapeutic index in antimicrobial drugs?

    <p>To compare the blood concentration where a drug becomes toxic versus its effective dosage.</p> Signup and view all the answers

    Which compound disrupts mycolic acid synthesis?

    <p>Isoniazid</p> Signup and view all the answers

    Which agent is used in the disruption of cell membranes by targeting ergosterol?

    <p>Polyenes</p> Signup and view all the answers

    What is a key feature of semisynthetic antibiotics compared to natural antibiotics?

    <p>They are easier to administer and more effective against multiple types of bacteria.</p> Signup and view all the answers

    What is the main role of sulfonamides in antimicrobial therapy?

    <p>To interfere with nucleotide synthesis.</p> Signup and view all the answers

    What is the thermal death point?

    <p>The lowest temperature that kills all cells in 10 minutes</p> Signup and view all the answers

    What is the effect of lyophilization on microbial cultures?

    <p>It provides long-term preservation of microbial cultures</p> Signup and view all the answers

    What type of radiation is known to cause pyrimidine dimers in DNA?

    <p>Ultraviolet (UV) light</p> Signup and view all the answers

    What is the primary purpose of osmotic pressure in food preservation?

    <p>To inhibit microbial growth by causing cells to lose water</p> Signup and view all the answers

    Which method is most effective for sterilizing powders and oils?

    <p>Dry heat</p> Signup and view all the answers

    What is the term used to describe the ability of a microorganism to cause disease?

    <p>Pathogenicity</p> Signup and view all the answers

    Which of the following is NOT a mode of disease transmission?

    <p>Environmental transmission</p> Signup and view all the answers

    Which virulence factor helps bacteria evade phagocytosis?

    <p>Bacterial capsule</p> Signup and view all the answers

    What defines an epidemic in terms of disease occurrence?

    <p>Disease occurrence at a greater than normal frequency</p> Signup and view all the answers

    What stage of infectious disease is characterized by the most severe symptoms?

    <p>Illness</p> Signup and view all the answers

    Which type of toxin is produced by Gram-negative bacteria?

    <p>Endotoxins</p> Signup and view all the answers

    What is the term for the presence of toxins in the bloodstream?

    <p>Toxemia</p> Signup and view all the answers

    What is the role of attachment antagonists in viral infection?

    <p>Block the attachment of the virus to receptor proteins.</p> Signup and view all the answers

    Which of the following factors is NOT considered a part of hospital epidemiology?

    <p>Zoonotic</p> Signup and view all the answers

    Opportunistic pathogens are typically part of the normal microbiota but can cause disease under what conditions?

    <p>During periods of immune suppression or stress.</p> Signup and view all the answers

    Which of the following mechanisms is NOT a way bacteria can resist antimicrobial drugs?

    <p>Enhancing drug entry into the cell.</p> Signup and view all the answers

    What type of reservoir is a human carrier who is in the incubatory phase of an infection?

    <p>Incubatory reservoir.</p> Signup and view all the answers

    Contamination and infection differ in that contamination refers to what?

    <p>The mere presence of microbes in the body.</p> Signup and view all the answers

    In which of the following instances would the parenteral route be used?

    <p>Directly depositing microorganisms into tissues via a needle.</p> Signup and view all the answers

    Which of the following best describes 'synergism' in the context of drug interactions?

    <p>One drug enhances the effect of a second drug.</p> Signup and view all the answers

    Which of the following is considered a non-living reservoir of infection?

    <p>Soil contaminated with pathogens.</p> Signup and view all the answers

    What is the primary consequence of using antimicrobial drugs on resident microbiota?

    <p>Opportunity for other microorganisms to thrive</p> Signup and view all the answers

    Which phase of microbial control focuses on killing all viruses and microorganisms on an object?

    <p>Sterilization</p> Signup and view all the answers

    What method is characterized by the removal of microorganisms by mechanical means?

    <p>Degerming</p> Signup and view all the answers

    Which of the following is NOT a part of the public health role in limiting disease transmission?

    <p>Initiating antibiotic treatments</p> Signup and view all the answers

    Which biosafety level is characterized by pathogens that do NOT cause disease in healthy humans?

    <p>Level 1</p> Signup and view all the answers

    What is the main effect of extreme heat and chemicals on proteins during antimicrobial action?

    <p>Denatures proteins</p> Signup and view all the answers

    Which method specifically involves using heat to destroy pathogens and reduce spoilage in food and beverages?

    <p>Pasteurization</p> Signup and view all the answers

    Which term refers to the reduction in the number of microorganisms on living tissue?

    <p>Antisepsis</p> Signup and view all the answers

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