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Questions and Answers
What is the main characteristic of supercritical fluids mentioned in the text?
What is the main characteristic of supercritical fluids mentioned in the text?
- Low density (correct)
- High viscosity
- Low dissolution capacity
- High vapor pressure
In the RESS technique, how is the solute precipitated from the supercritical fluid?
In the RESS technique, how is the solute precipitated from the supercritical fluid?
- By increasing the solvent density
- By rapid expansion reducing solvent density (correct)
- By using a high-pressure system
- By increasing the temperature
What is the purpose of the SAS technique in supercritical fluid technology?
What is the purpose of the SAS technique in supercritical fluid technology?
- To increase solvent density
- To act as an anti-solvent for the drug (correct)
- To act as a solvent for the drug
- To decrease drug solubility
In crystallization by precipitation, what are the two methods mentioned for inducing precipitation?
In crystallization by precipitation, what are the two methods mentioned for inducing precipitation?
What is a critical property mentioned in the text for N2 (Nitrogen)?
What is a critical property mentioned in the text for N2 (Nitrogen)?
Which method of crystallization involves the addition of an anti-solvent that is miscible with the solvent?
Which method of crystallization involves the addition of an anti-solvent that is miscible with the solvent?
What is the purpose of supercritical fluid technology in the context of drug particles?
What is the purpose of supercritical fluid technology in the context of drug particles?
Which process involves the particles precipitating and the solvent being extracted into the supercritical fluid?
Which process involves the particles precipitating and the solvent being extracted into the supercritical fluid?
In supercritical fluid technology, what happens to the drug particles?
In supercritical fluid technology, what happens to the drug particles?
What are two phase systems used for in the context of crystallization?
What are two phase systems used for in the context of crystallization?
Which reading source is recommended for understanding solid state properties and crystallization?
Which reading source is recommended for understanding solid state properties and crystallization?
What changes typically occur to substances during the process of cooling crystallization?
What changes typically occur to substances during the process of cooling crystallization?
What does Lysozyme represent in the context of 'Two phase systems'?
What does Lysozyme represent in the context of 'Two phase systems'?
What is the main focus of physical stability in pharmaceuticals?
What is the main focus of physical stability in pharmaceuticals?
How are crystals defined in the text?
How are crystals defined in the text?
What is the characteristic of amorphous material?
What is the characteristic of amorphous material?
In terms of physical stability, what is an indirect effect of chemical stability?
In terms of physical stability, what is an indirect effect of chemical stability?
Which method of crystallization is mentioned in the text?
Which method of crystallization is mentioned in the text?
What is the focus of supercritical fluid technology in the context of pharmaceuticals?
What is the focus of supercritical fluid technology in the context of pharmaceuticals?
What is the purpose of supersaturation in the process of crystallization from a solution?
What is the purpose of supersaturation in the process of crystallization from a solution?
In crystallization, what is the role of anti-solvent?
In crystallization, what is the role of anti-solvent?
Which method can be used to introduce anti-solvent in the crystallization process?
Which method can be used to introduce anti-solvent in the crystallization process?
What is heterogeneous nucleation in the context of crystallization?
What is heterogeneous nucleation in the context of crystallization?
What role does evaporation play in the crystallization process?
What role does evaporation play in the crystallization process?
How does cooling contribute to crystallization from a solution?
How does cooling contribute to crystallization from a solution?
What is the main purpose of nucleation in the crystallization process?
What is the main purpose of nucleation in the crystallization process?
Define chemical stability in pharmaceuticals.
Define chemical stability in pharmaceuticals.
Explain the concept of physical stability in pharmaceutical products.
Explain the concept of physical stability in pharmaceutical products.
What is the purpose of supersaturation in the crystallization process from a solution?
What is the purpose of supersaturation in the crystallization process from a solution?
Describe the main characteristic of ideal crystals.
Describe the main characteristic of ideal crystals.
What is the characteristic of amorphous material?
What is the characteristic of amorphous material?
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