MPharm Programme Introduction to Microbiology Textbooks

Microbiology is the generic term for the study of ______

Microbiology studies individual microbes and also communities of ______

Microbiology has a huge impact in a variety of fields such as fermented foods, baking, brewing, and wine making as well as water and sewage ______

Microbiology plays an important role in studying pathogens and infectious ______

Microbiology is relevant in the fields of human health and wellbeing, pharmaceuticals, and ______

Microorganisms (microbes) are ______ (1,000,000 tonnes/year produced)

Alkaline proteases digest protein-based ______ > 1,000 tonnes/year produced

Natural products of microbial origin include: ______

Cholesterol lowering-agents ______ (Fungi)

Bacteria can be genetically modified to produce therapeutic ______; e.g Insulin (humulin)

Gardasil Targets Human papilloma virus (HPV) Contains recombinant viral protein produced in a ______

Microbial spoilage can be defined as the deterioration of a product by a contaminating ______

Practical microbiology: Growing microbes. In general, microbes can be grown in the laboratory using solid or liquid ______

Specialist media exists... Identify unknown ______

Practical microbiology: Looking at microbes. Viruses, Bacteria, ______

Chicken Egg (~40-50mm). 1mm 10mm Naked eye Light microscope Electron ______

Practical microbiology: Molecular microbiology Extract genetic components DNA Targeted regions e.g ______

Prescott’s Microbiology (8th ed.) Publisher: McGraw- Hill Higher Education is a textbook used in the __________ Programme

Microbiology has a huge impact in a variety of fields such as fermented foods, baking, brewing, and wine making as well as water and sewage __________

Microbiology studies individual microbes and also communities of __________

Microorganisms (microbes) are ______ (1,000,000 tonnes/year produced)

Microbial spoilage can be defined as the deterioration of a product by a contaminating ______

Learning Objectives Gain awareness of basic microbiology principles What is microbiology What are microorganisms How do we study microbes Describe and provide examples of relevant areas in which microbiology plays an important role Human health and wellbeing ______

Practical microbiology: Molecular microbiology Extract genetic components DNA Targeted regions e.g ______

Microbial spoilage can be defined as the deterioration of a product by a contaminating ____

Gardasil Targets Human papilloma virus (HPV) Contains recombinant viral protein produced in a ______

Alkaline proteases digest protein-based ______; > 1,000 tonnes/year produced

Microbiology has a huge impact in a variety of fields such as fermented foods, baking, brewing, and wine making as well as water and sewage ______

Cholesterol lowering-agents ______ (Fungi)

Microorganisms (microbes) are ______ (1,000,000 tonnes/year produced)

Practical microbiology: Looking at microbes. Viruses, Bacteria, ____

Microorganisms (microbes) are microscopic ______ (1,000,000 tonnes/year produced)

Alkaline proteases digest protein-based ______ > 1,000 tonnes/year produced

Cholesterol lowering-agents ______ (Fungi)

Proteases Bacillus licheniformis (bacterium) Produces alkaline protease in response to nutrient limitation Enzymes used in laundry detergent Alkaline proteases digest protein-based ______ > 1,000 tonnes/year produced

Natural products of microbial origin include: Antimicrobials Penicillins, streptomycin (Fungi) Endolysins (Viral) Cholesterol lowering-agents ______ (Fungi)

Biotechnology: natural medicinal products Natural products of microbial origin include: Antimicrobials Penicillins, streptomycin (Fungi) Endolysins (Viral) Cholesterol lowering-agents Lovastatin (Fungi) Neurotoxins ______ toxin (Bacteria) Biotechnology: recombinant medicinal products Bacteria can be genetically modified to produce therapeutic proteins; e.g Insulin (humulin) First produced in 1978 by Genetech then licenced to Eli Lilly In use > 25 years Recombinant Vaccines e.g.

Biotechnology: recombinant medicinal products Bacteria can be genetically modified to produce therapeutic proteins; e.g Insulin (humulin) First produced in 1978 by Genetech then licenced to Eli Lilly In use > 25 years Recombinant Vaccines e.g.