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MPharm PHA112 Enzymes Lectures Summary
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MPharm PHA112 Enzymes Lectures Summary

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Questions and Answers

What is the primary function of enzymes?

  • Transcription of DNA
  • Acting as catalysts for chemical reactions (correct)
  • Cellular respiration
  • Synthesis of RNA
  • What is the most common type of enzymes?

  • Globular proteins (correct)
  • Fibrous proteins
  • RNA
  • Lipids
  • Which of the following is an example of RNA that can act as an enzyme?

  • Ribosomal RNA
  • Transfer RNA
  • Messenger RNA
  • Ribozymes (correct)
  • What determines the specificity of enzymes for their substrates?

    <p>Shape of the enzyme's active site</p> Signup and view all the answers

    Which plot is associated with enzyme kinetics?

    <p>Michaelis-Menten Plot</p> Signup and view all the answers

    How do small changes in pH affect enzyme function?

    <p>Altered critical ionization states affect the binding of the substrate with the enzyme active site</p> Signup and view all the answers

    What is the optimum pH range for most human enzymes?

    <p>pH 6-8</p> Signup and view all the answers

    How does extreme pH levels affect enzymes?

    <p>Extreme pH levels cause enzyme denaturation, disrupting the enzyme's 3D shape and active site</p> Signup and view all the answers

    How does changes in salinity affect enzyme function?

    <p>Changes in salinity disrupt attraction between charged amino acids and affect enzyme structure</p> Signup and view all the answers

    What is the study of the rates of chemical reactions catalyzed by enzymes called?

    <p>Enzyme Kinetics</p> Signup and view all the answers

    Study Notes

    Functions and Types of Enzymes

    • Enzymes primarily function as biological catalysts, speeding up chemical reactions in living organisms.
    • The most common type of enzymes are globular proteins that facilitate metabolic processes by lowering activation energy.

    RNA and Enzymatic Activity

    • Ribozymes are examples of RNA that can act as enzymes, exhibiting catalytic properties similar to proteins.

    Enzyme Specificity

    • Enzyme specificity for substrates is determined by the unique three-dimensional shape of the enzyme and the active site's compatibility with the substrate.

    Enzyme Kinetics

    • The Michaelis-Menten plot is associated with enzyme kinetics, illustrating the relationship between substrate concentration and reaction rate.

    pH and Enzyme Function

    • Small changes in pH can affect enzyme function by altering the charge and shape of the active site, potentially diminishing catalytic activity.
    • The optimum pH range for most human enzymes is typically around 6 to 8, where they exhibit peak activity.

    Effects of Extreme pH

    • Extreme pH levels can lead to denaturation of enzymes, resulting in the loss of their functional shape and activity.

    Salinity and Enzyme Function

    • Changes in salinity can influence enzyme function, as ions can disrupt the ionic bonds and interactions that maintain enzyme structure.

    Enzyme Reaction Rates

    • The study of the rates of chemical reactions catalyzed by enzymes is known as enzyme kinetics, focusing on how factors like substrate concentration and environmental conditions affect reaction speeds.

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    Related Documents

    Enzymes 1 (2023).pdf
    Enzymes 2 (2023).pdf

    Description

    Summary of lectures for MPharm PHA112 Enzymes covering enzyme structure, classification, co-factors, cellular metabolism, enzyme function, substrate interaction, kinetics, and inhibition.

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