Podcast
Questions and Answers
How does the orientation of the 1-OH group affect glucose?
How does the orientation of the 1-OH group affect glucose?
- It alters the number of covalent bonds within the glucose molecule.
- It distinguishes glucose from other monosaccharides like fructose.
- It determines whether glucose is a disaccharide or a polysaccharide.
- It results in two isomers (α or β) of glucose. (correct)
What characteristic of monosaccharides facilitates their transportation between cells?
What characteristic of monosaccharides facilitates their transportation between cells?
- Their polar and hydrophilic nature. (correct)
- Their non-polar molecular structure.
- Their ability to form complex associations with proteins.
- Their relatively large molecular weight.
Which process allows energy stored in the covalent bonds of monosaccharides to be released?
Which process allows energy stored in the covalent bonds of monosaccharides to be released?
- Hydrolysis.
- Condensation.
- Isomerization.
- Oxidation via cellular respiration. (correct)
What dictates the properties of the polymer formed from monosaccharides?
What dictates the properties of the polymer formed from monosaccharides?
In what form do organisms typically store glucose for later use?
In what form do organisms typically store glucose for later use?
What type of reaction creates a glycosidic bond?
What type of reaction creates a glycosidic bond?
If a researcher is studying the energy source that cells primarily utilize, which monosaccharide should they focus on?
If a researcher is studying the energy source that cells primarily utilize, which monosaccharide should they focus on?
A scientist discovers a new disaccharide composed of two glucose molecules. What is this disaccharide most likely to be?
A scientist discovers a new disaccharide composed of two glucose molecules. What is this disaccharide most likely to be?
Which of the following is NOT a characteristic of monosaccharides?
Which of the following is NOT a characteristic of monosaccharides?
What kind of molecule is a glycoprotein?
What kind of molecule is a glycoprotein?
How does the presence of double bonds in unsaturated fatty acids affect their physical properties, compared to saturated fatty acids?
How does the presence of double bonds in unsaturated fatty acids affect their physical properties, compared to saturated fatty acids?
Which statement best describes why saturated fats are typically solid at room temperature?
Which statement best describes why saturated fats are typically solid at room temperature?
A scientist is analyzing a lipid sample and finds it is liquid at room temperature and contains multiple double bonds. What type of fatty acid is most likely present?
A scientist is analyzing a lipid sample and finds it is liquid at room temperature and contains multiple double bonds. What type of fatty acid is most likely present?
How does the molecular structure of unsaturated fatty acids affect the way they pack together, and what is the consequence of this packing?
How does the molecular structure of unsaturated fatty acids affect the way they pack together, and what is the consequence of this packing?
Which structural feature of saturated fatty acids allows them to have higher melting points compared to unsaturated fatty acids?
Which structural feature of saturated fatty acids allows them to have higher melting points compared to unsaturated fatty acids?
A food manufacturer is deciding between using saturated or unsaturated fats in a product. They need a fat that remains solid at room temperature. Which type of fat should they choose and why?
A food manufacturer is deciding between using saturated or unsaturated fats in a product. They need a fat that remains solid at room temperature. Which type of fat should they choose and why?
How do the intermolecular forces differ between saturated and unsaturated fatty acids, and how does this difference manifest in their physical state at room temperature?
How do the intermolecular forces differ between saturated and unsaturated fatty acids, and how does this difference manifest in their physical state at room temperature?
What is the primary structural difference between monounsaturated and polyunsaturated fatty acids, and how does this difference affect their properties?
What is the primary structural difference between monounsaturated and polyunsaturated fatty acids, and how does this difference affect their properties?
Why do plants in warmer climates tend to produce more saturated fats compared to those in cooler climates?
Why do plants in warmer climates tend to produce more saturated fats compared to those in cooler climates?
Why are unsaturated fatty acids less likely to contribute to the formation of fatty deposits in blood vessels compared to saturated fatty acids?
Why are unsaturated fatty acids less likely to contribute to the formation of fatty deposits in blood vessels compared to saturated fatty acids?
How do trans fatty acids differ structurally from cis-unsaturated fatty acids, and what is the consequence of this difference?
How do trans fatty acids differ structurally from cis-unsaturated fatty acids, and what is the consequence of this difference?
Why are trans fats considered particularly unhealthy compared to other types of fats?
Why are trans fats considered particularly unhealthy compared to other types of fats?
How does the production of trans fats typically occur?
How does the production of trans fats typically occur?
What are the two key functions of adipose tissue in animals?
What are the two key functions of adipose tissue in animals?
How does blubber, a specialized form of adipose tissue in marine mammals, contribute to their survival in aquatic environments?
How does blubber, a specialized form of adipose tissue in marine mammals, contribute to their survival in aquatic environments?
Why are triglycerides considered effective as a long-term energy storage molecule?
Why are triglycerides considered effective as a long-term energy storage molecule?
Which of the following statements accurately describes the roles of estradiol and testosterone?
Which of the following statements accurately describes the roles of estradiol and testosterone?
Why does continual over-eating lead to the accumulation of adipose tissue?
Why does continual over-eating lead to the accumulation of adipose tissue?
What is the basic structural unit of steroids?
What is the basic structural unit of steroids?
What characteristic of proteins enables them to perform a wide range of functions within a cell?
What characteristic of proteins enables them to perform a wide range of functions within a cell?
How does the non-polar and hydrophobic nature of steroids affect their function in the body?
How does the non-polar and hydrophobic nature of steroids affect their function in the body?
How do protein expression levels adjust to meet cellular requirements?
How do protein expression levels adjust to meet cellular requirements?
Which chemical groups are common to all amino acids?
Which chemical groups are common to all amino acids?
What is the precursor molecule from which steroid hormones are synthesized?
What is the precursor molecule from which steroid hormones are synthesized?
Which of the following is an example of a steroid hormone?
Which of the following is an example of a steroid hormone?
If an amino acid is described as 'essential,' what does this imply about its availability to an organism?
If an amino acid is described as 'essential,' what does this imply about its availability to an organism?
How do the solubility properties of triglycerides relate to their function as a long-term energy storage molecule?
How do the solubility properties of triglycerides relate to their function as a long-term energy storage molecule?
Under what circumstances might a conditional amino acid become essential?
Under what circumstances might a conditional amino acid become essential?
If a plant species is introduced from a cold climate to a warmer climate, what changes in its lipid composition might be expected over several generations?
If a plant species is introduced from a cold climate to a warmer climate, what changes in its lipid composition might be expected over several generations?
Consider a scenario where a cell is deficient in a particular non-essential amino acid. What mechanism would the cell most likely employ to address this deficiency?
Consider a scenario where a cell is deficient in a particular non-essential amino acid. What mechanism would the cell most likely employ to address this deficiency?
A researcher analyzes a newly discovered organism and finds that its proteins are composed of only 15 different amino acids. What would be a valid conclusion based on this observation?
A researcher analyzes a newly discovered organism and finds that its proteins are composed of only 15 different amino acids. What would be a valid conclusion based on this observation?
A patient has a metabolic disorder that impairs their ability to convert one non-essential amino acid into another. How should their diet be modified to address this issue?
A patient has a metabolic disorder that impairs their ability to convert one non-essential amino acid into another. How should their diet be modified to address this issue?
During periods of intense physical stress, such as recovery from severe burns, the body's demand for certain amino acids increases significantly. How does this change affect the classification of some amino acids?
During periods of intense physical stress, such as recovery from severe burns, the body's demand for certain amino acids increases significantly. How does this change affect the classification of some amino acids?
How does altering the isoelectric point (pI) of an amino acid typically affect its properties within a protein?
How does altering the isoelectric point (pI) of an amino acid typically affect its properties within a protein?
Which of the following best describes the central dogma of molecular biology regarding protein synthesis?
Which of the following best describes the central dogma of molecular biology regarding protein synthesis?
What is the primary role of transcription in protein expression?
What is the primary role of transcription in protein expression?
How can alternative splicing increase protein diversity, and why is this important?
How can alternative splicing increase protein diversity, and why is this important?
What is the significance of post-translational modifications in protein function?
What is the significance of post-translational modifications in protein function?
Given that the human genome encodes approximately 20,000 proteins, how can the human proteome include approximately 100,000 proteins?
Given that the human genome encodes approximately 20,000 proteins, how can the human proteome include approximately 100,000 proteins?
How would a mutation affecting the splice sites within a gene most likely impact the resulting protein?
How would a mutation affecting the splice sites within a gene most likely impact the resulting protein?
Which of the following describes a scenario where a gene does not get translated?
Which of the following describes a scenario where a gene does not get translated?
What is a 'proteome', and how does it differ from the genome?
What is a 'proteome', and how does it differ from the genome?
Considering post-translational modifications, which of the following modifications is most likely to influence protein-protein interactions?
Considering post-translational modifications, which of the following modifications is most likely to influence protein-protein interactions?
What structural feature distinguishes amylopectin from amylose?
What structural feature distinguishes amylopectin from amylose?
Which characteristic of cellulose contributes most to its mechanical stability?
Which characteristic of cellulose contributes most to its mechanical stability?
What is the primary function of glycoproteins, in the context of cell recognition?
What is the primary function of glycoproteins, in the context of cell recognition?
Which of the following properties is characteristic of non-polar molecules, such as lipids, that defines their interaction with water?
Which of the following properties is characteristic of non-polar molecules, such as lipids, that defines their interaction with water?
What type of reaction is involved in the formation of ester linkages in lipids?
What type of reaction is involved in the formation of ester linkages in lipids?
How does the structure of phospholipids contribute to their ability to form biological membranes?
How does the structure of phospholipids contribute to their ability to form biological membranes?
Which of the following best explains why animals store energy as fats rather than as glycogen?
Which of the following best explains why animals store energy as fats rather than as glycogen?
How does the presence of double bonds in unsaturated fatty acids affect their physical properties?
How does the presence of double bonds in unsaturated fatty acids affect their physical properties?
How do waxes provide effective water-repelling surfaces in plants and animals?
How do waxes provide effective water-repelling surfaces in plants and animals?
In the context of lipid classification, how are derived lipids different from simple and compound lipids?
In the context of lipid classification, how are derived lipids different from simple and compound lipids?
What is the role of the endoplasmic reticulum and Golgi body in the context of glycoproteins
What is the role of the endoplasmic reticulum and Golgi body in the context of glycoproteins
What is the significance of 1'-4' and 1'-6' linkages in polysaccharides like starch and glycogen?
What is the significance of 1'-4' and 1'-6' linkages in polysaccharides like starch and glycogen?
How does the alternating arrangement of $\beta$-glucose monomers affect the structure of cellulose?
How does the alternating arrangement of $\beta$-glucose monomers affect the structure of cellulose?
What is the role of thermal insulation in lipids and their properties?
What is the role of thermal insulation in lipids and their properties?
Considering the chemical structure, what makes saturated fatty acids different from unsaturated fatty acids?
Considering the chemical structure, what makes saturated fatty acids different from unsaturated fatty acids?
Flashcards
Glucose
Glucose
A simple sugar and primary energy source for cells.
Isomers
Isomers
Different compounds with the same molecular formula but different structures.
Monosaccharides
Monosaccharides
Single sugar molecules that are the building blocks of carbohydrates.
Hydrophilic
Hydrophilic
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Cellular Respiration
Cellular Respiration
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ATP
ATP
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Glycosidic Bond
Glycosidic Bond
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Disaccharide
Disaccharide
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Polysaccharides
Polysaccharides
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Starch
Starch
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Saturated Fatty Acids
Saturated Fatty Acids
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Melting Point
Melting Point
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Intermolecular Forces
Intermolecular Forces
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Unsaturated Fatty Acids
Unsaturated Fatty Acids
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Double Bonds
Double Bonds
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Mono-unsaturated
Mono-unsaturated
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Polyunsaturated
Polyunsaturated
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Kinked Chains
Kinked Chains
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Estradiol
Estradiol
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Testosterone
Testosterone
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Proteins
Proteins
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Macromolecule
Macromolecule
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Protein Synthesis
Protein Synthesis
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Amino Acids
Amino Acids
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Essential Amino Acids
Essential Amino Acids
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Non-Essential Amino Acids
Non-Essential Amino Acids
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Conditional Amino Acids
Conditional Amino Acids
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Protein Expression Levels
Protein Expression Levels
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Amino Acid Charge
Amino Acid Charge
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Protein Structure
Protein Structure
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Gene Expression
Gene Expression
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Transcription
Transcription
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Translation
Translation
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Proteome
Proteome
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Alternative Splicing
Alternative Splicing
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Post-Translational Modifications
Post-Translational Modifications
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Polypeptide Variability
Polypeptide Variability
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Human Proteins
Human Proteins
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Energy Storage Polymers
Energy Storage Polymers
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Glycogen Structure
Glycogen Structure
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Starch Types
Starch Types
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Cellulose
Cellulose
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Microfibrils
Microfibrils
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Glycoproteins
Glycoproteins
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Glycosylation
Glycosylation
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Lipids
Lipids
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Amphipathic Molecules
Amphipathic Molecules
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Triglycerides
Triglycerides
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Phospholipids
Phospholipids
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Condensation Reaction
Condensation Reaction
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Derived Lipids
Derived Lipids
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Hydrogen Bonds in Cellulose
Hydrogen Bonds in Cellulose
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Unsaturated oils
Unsaturated oils
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Saturated fats in plants
Saturated fats in plants
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Atherosclerosis
Atherosclerosis
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Cis vs Trans fatty acids
Cis vs Trans fatty acids
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Trans fats
Trans fats
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Adipose tissue
Adipose tissue
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Blubber
Blubber
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Solubility of triglycerides
Solubility of triglycerides
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Osmotic pressure
Osmotic pressure
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Energy yield of triglycerides
Energy yield of triglycerides
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Steroids
Steroids
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Steroid hormones
Steroid hormones
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Intracellular receptors
Intracellular receptors
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Fatty deposits
Fatty deposits
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Study Notes
Carbohydrates
- Made of C, H, and O (typically in the ratio CHâ‚‚O)â‚™
- Monosaccharides are the repeating monomers, forming simple sugars
- Monosaccharides form ring structures, which is more energetically favorable
- Monosaccharides - most have 5 carbons (pentose sugars) or 6 carbons (hexose sugars)
- Examples of pentoses include ribose and deoxyribose
- Glucose, a hexose sugar, is a primary energy source in cells.
- Isomers exist for glucose with different orientations, examples a-glucose and ß-glucose
Energy Source
- Primary role: chemical energy, often glucose
- Energy stored in covalent bonds, released via cellular respiration
- Smaller, polar molecules making them hydrophilic and easy transport between cells
- Glucose converted to starch or glycogen for storage
Polysaccharides
- Glycosidic bonds form in condensation reactions, linking monosaccharides
- Disaccharides: two monosaccharides linked together (e.g., maltose, sucrose, lactose)
- Polysaccharides can be complexed with other molecules (e.g., glycoproteins)
- Energy storage polymers:
- Glycogen (animals)
- Starch (plants)
- Amylose: helical, 1-4' linkages
- Amylopectin: branched, additional 1-6' linkages
- Structure
- Cellulose: linear chains of β-glucose with alternating arrangements. Hydrogen bonds increase mechanical stability, forming microfibrils.
Recognition
- Glycoproteins: proteins with attached carbohydrates via glycosidic linkages.
- Glycosylation occurs in the endoplasmic reticulum or Golgi body
- ABO blood types are examples of glycoproteins on red blood cells.
Lipids
- Nonpolar molecules, some with polar regions (amphipathic)
- Roles: energy storage, thermal insulation, membrane structure, signaling
- Properties: nonpolar, low solubility in polar solvents, aggregate in aqueous solvents
- Types of Lipids
- Simple lipids:
- Triglycerides (fats and oils), waxes
- Compound lipids:
- Phospholipids, glycolipids
- Derived lipids:
- Steroids, prostaglandins
- Simple lipids:
- Ester linkages: fatty acid chains covalently linked to an alcohol group via condensation reactions
- Triglycerides: 3 fatty acid chains linked to a glycerol
- Phospholipids: one fatty acid replaced by a polar phosphate group
Fatty Acids
- Saturated: no double bonds, straight chains, solid at room temp (higher melting point)
- Unsaturated: one or more double bonds, kinked chains, liquid at room temp (lower melting point)
- Fats vs. Oils - based on saturation level and their respective properties
- Endotherms store more saturated fats
- Plants in warmer climates store more saturated fats compared to plants in cooler climates
Health Consequences
- Saturated fats tend to stay solid at high temperatures → more likely to form deposits in blood vessels, leading to atherosclerosis and high blood pressure.
- Unsaturated fats stay liquid → less likely to clog blood vessels.
- Trans fats: unsaturated fatty acids with different arrangements, acting more like saturated fats and raising cholesterol levels.
- Industrial cooking processes produce trans fats.
- Triglycerides store energy in adipose tissue, providing thermal insulation and buoyancy.
Steroids
- Derived lipids composed of four fused carbon rings
- Signaling molecules (hormones): pass through the phospholipid bilayer and bind to intracellular receptors
- Examples: oestrogen (produced by ovaries) and testosterone (produced by testes)
Proteins
-
Extremely diverse organic compounds, fulfilling a wide range of functions
-
Made of amino acids
-
Amino acids have an amine group, carboxyl group, and variable group.
-
Types of amino acids exist:
- Essential: body cannot synthesize, must be obtained from the diet.
- Nonessential: body can synthesize.
- Conditional: body may synthesize but under certain conditions (e.g., pregnancy).
-
Protein folding: amino acid sequence determines the 3D structure, crucial for function
-
Protein functions include: structure, hormones, immunity, transport, sensitivity, movement and enzymes
-
Denaturation: Change in protein structure due to factors like temperature or pH changes, leading to loss of biological activity.
Proteome
- Total proteins expressed within a cell or organism at a given time
- Larger than the totality of genes due to alternative splicing.
- Protein expression levels change with the requirements of the cell, controlled by genetic instructions.
Nucleic Acids
- Store genetic instructions and pass them between generations
- Two types:
- DNA: Deoxyribonucleic acid (double-stranded)
- RNA: Ribonucleic acid (single-stranded)
- Nucleotides: monomers consisting of a pentose sugar, phosphate group and a nitrogenous base
- Purines (adenine, guanine)
- Pyrimidines (cytosine, thymine, uracil)
- DNA and RNA structures: DNA is a double helix , RNA is a single strand. Each have a backbones, which are combinations of sugars and phosphates
###DNA Organization
- Prokaryotes have circular chromosomes (unpackaged form)
- Eukaryotes have linear chromosomes with packaged DNA (DNA and histone proteins form chromatin)
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