Monoclonal Antibodies in Medicine
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Questions and Answers

What substance is used to facilitate the fusion of myeloma cells with immune spleen cells?

  • Freund's adjuvant
  • Polyethylene glycol (PEG) (correct)
  • Monoclonal antibodies
  • Thymidine

    • What type of medium is used to select for hybridoma cells after fusion?

  • HAT medium (correct)
  • RPMI 1640
  • LB broth
  • DMEM

    • Which method can be used for cloning hybridoma cell lines?

  • Polymerase chain reaction
  • Injection into mouse peritoneal cavity (correct)
  • Thermal cycling
  • Optical imaging

    • What is a common diagnostic application of monoclonal antibodies?

    <p>Blood typing</p> Signup and view all the answers

    Chimeric antibodies are beneficial because they contain which type of portion?

    <p>Human Fc portion</p> Signup and view all the answers

    What role do monoclonal antibodies play in cancer treatment?

    <p>Coupling with radioactive atoms to kill cancer cells</p> Signup and view all the answers

    Which of the following is an incorrect application of monoclonal antibodies?

    <p>Enhancing the immune response through vaccines</p> Signup and view all the answers

    What is a step involved in ensuring sufficient immune response in mice before hybridoma cell production?

    <p>Measuring serum antibody titers</p> Signup and view all the answers

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