Podcast Beta
Questions and Answers
What is the definition of a drug?
A drug is any chemical or biological substance, synthetic or non-synthetic, intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in man or other animals.
Give an example of a source of synthetic drugs.
Propranolol
Name one source of biological drugs.
Penicillin
Why are new drugs needed?
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What are some examples of unmet medical needs mentioned in the text?
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What are the downstream health costs mentioned in the text?
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What are some factors contributing to the cost of therapy according to the text?
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What is the term used for the occasional discovery of new drugs by luck?
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Who discovered the antibiotic penicillin by accident?
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What drug was considered just a better tolerable prodrug of salicylic acid but turned out to have a unique mechanism?
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What use was initially thought for phenolphthalein before its drastic diarrheal activity was discovered?
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What was warfarin originally used for before its current medical use?
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What was the basis for preparing nitro derivatives used in angina treatment?
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What led to the discovery of drugs used in leukemia to inhibit excessive proliferation of white blood cells?
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What is the approach of screening a large number of chemical compounds or natural products for a desired effect called?
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What are some drawbacks of the random screening approach for drug development?
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