6 Questions
Supercoiling refers to the higher-level coiling of DNA that is already a complementary strand.
True
Catenanes are linear molecules of DNA that become interlocked during transcription.
False
An enhancer is a regulatory sequence located close to the promoter region.
False
A primary transcript is the modified RNA molecule obtained after the initial transcription from a DNA template.
False
Housekeeping genes are switched on all of the time because they are needed for essential life functions.
False
The Pribnow box is a region of bacterial promoter located 10 bases upstream from the start of transcription.
True
Study Notes
Molecular Biology Terms
- Supercoiling: Higher level coiling of DNA that is already a complementary strand.
- Catenanes: Circular molecules of DNA may become interlocked during transcription or recombination.
- Open Reading Frame: Sequence of bases (either in DNA or RNA) that can be translated to give a protein.
- Constitutive Gene: Often have both their -10 and -35 region promoter sequences very close to consensus, which are repressed under rare conditions.
- Enhancer: Regulatory sequence inside, and often far away from, the promoter region that binds transcription factors.
- 5'-UTR: Region of an mRNA between the 5' end and the translation start site.
- Primary Transcript: The original RNA molecule obtained by transcription from a DNA template, before any processing or modification has occurred.
- Housekeeping Genes: Genes that are switched on some of the time because they are needed for essential life functions.
- Pribnow Box: Region of bacterial promoter 10 bases back from the start of transcription that is recognized by RNA polymerase.
Test your knowledge of key molecular biology terms, including supercoiling, catenanes, open reading frames, and constitutive genes.
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