Molecular Biology: Insertional Mutagenesis and Oncogenes
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Questions and Answers

What is the most common type of inherited cancer syndrome?

  • X-linked dominant
  • Mitochondrial inheritance
  • Autosomal dominant (correct)
  • Autosomal recessive

What is the result of non-lethal genetic damage in terms of cancer development?

  • Carcinoma
  • Cancer (correct)
  • Apoptosis
  • Leukemia

What is the relationship between oncogenes and protooncogenes?

  • Oncogenes are normal growth/differentiation genes
  • Oncogenes are CA-causing derivatives of tumor suppressors
  • Oncogenes are CA-causing derivatives of protooncogenes (correct)
  • Oncogenes are DNA repair genes

What is the most common type of cancer in terms of incidence in men?

<p>Prostate (A)</p> Signup and view all the answers

What is the consequence of defective DNA repair genes?

<p>Cancer (C)</p> Signup and view all the answers

What is the example of autosomal recessive syndrome of DNA repair?

<p>Xeroderma pigmentosum (B)</p> Signup and view all the answers

What is the primary function of cyclin D in the cell cycle?

<p>Phosphorylating Rb to release E2F (A)</p> Signup and view all the answers

Which of the following is a characteristic of oncogene activation?

<p>Change in structure or regulation of a proto-oncogene (A)</p> Signup and view all the answers

What is the primary function of p53 in response to DNA damage?

<p>Activating cell cycle checkpoints (C)</p> Signup and view all the answers

What is the term for the process by which tumor cells invade the ECM?

<p>Invasion (C)</p> Signup and view all the answers

Which of the following is a characteristic of a malignant tumor?

<p>Local invasion and metastases (A)</p> Signup and view all the answers

What is the term for the process by which tumor cells disseminate through the vascular system and home to specific organs?

<p>Vascular dissemination and homing (A)</p> Signup and view all the answers

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