Podcast
Questions and Answers
What is the main difference between insoluble polymer matrix systems and hydrophilic matrices?
What is the main difference between insoluble polymer matrix systems and hydrophilic matrices?
- Insoluble polymer matrices dissolve in water, while hydrophilic matrices do not.
- Insoluble polymer matrices have zero-order kinetics, while hydrophilic matrices do not.
- Insoluble polymer matrices stay intact in the gastrointestinal tract, while hydrophilic matrices do not. (correct)
- Insoluble polymer matrices release drug molecules through the membrane, while hydrophilic matrices do not.
Why is pore size and tortuosity important in controlling the drug release rate in insoluble polymer matrix systems?
Why is pore size and tortuosity important in controlling the drug release rate in insoluble polymer matrix systems?
- Pore size and tortuosity determine the color of the matrix.
- Pore size and tortuosity impact the weight of the matrix tablet.
- Pore size and tortuosity affect how drug molecules diffuse out of the matrix. (correct)
- Pore size and tortuosity regulate the temperature at which drug release occurs.
How does the presence of membrane differ between membrane-controlled systems and insoluble polymer matrix systems?
How does the presence of membrane differ between membrane-controlled systems and insoluble polymer matrix systems?
- Membrane-controlled systems have a higher tortuosity than insoluble polymer matrices.
- Membrane-controlled systems rely on a membrane for drug diffusion, while insoluble polymer matrices do not use a membrane. (correct)
- Membrane-controlled systems release drugs via pores, unlike insoluble polymer matrices.
- Membrane-controlled systems have drug molecules dispersed throughout the matrix, while insoluble polymer matrices do not.
Why does drug release from insoluble polymer matrix systems not follow zero-order kinetics?
Why does drug release from insoluble polymer matrix systems not follow zero-order kinetics?
What role do pore forming agents play in insoluble polymer matrix systems?
What role do pore forming agents play in insoluble polymer matrix systems?
Which factor greatly influences the drug release mechanism in insoluble polymer matrix systems?
Which factor greatly influences the drug release mechanism in insoluble polymer matrix systems?
How does a dry insoluble matrix tablet differ from a wet one in terms of drug diffusion?
How does a dry insoluble matrix tablet differ from a wet one in terms of drug diffusion?
What aspect does the rate-controlling part of membrane-controlled systems consist of?
What aspect does the rate-controlling part of membrane-controlled systems consist of?
How do membrane-controlled delivery systems differ from insoluble polymer matrix systems in terms of drug diffusion?
How do membrane-controlled delivery systems differ from insoluble polymer matrix systems in terms of drug diffusion?
What factors affect the control of drug release rate in insoluble polymer matrix systems?
What factors affect the control of drug release rate in insoluble polymer matrix systems?
Why is it essential for insoluble polymer matrices to stay intact throughout the gastrointestinal tract?
Why is it essential for insoluble polymer matrices to stay intact throughout the gastrointestinal tract?
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