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Mode of Action of Antimicrobials Quiz

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Questions and Answers

What is meant by selective toxicity in relation to antibiotics?

Binding easily to human cells

Causing minimal harm to the host organism

Disrupting a structure or process essential for microorganism growth and survival (correct)

Causing harm to the host organism

Why must antibiotics cause minimal harm to the host organism?

To cause disruption to a structure essential for microorganism growth and survival

To ensure they are therapeutic but not excessively toxic (correct)

To avoid binding easily to human cells

To increase their effectiveness against microorganisms

Which of the following is an essential requirement for antibiotics according to the text?

Causing minimal harm to the host organism

Binding easily to human cells

Causing disruption to a structure essential for microorganism growth and survival (correct)

Causing disruption to a structure not essential for microorganism growth and survival

Why is it important for some antibiotics to have a narrow therapeutic index?

To ensure they are therapeutic but not excessively toxic Signup and view all the answers

Which scenario represents selective toxicity in antibiotics?

The antibiotic target is absent in human cells but present in the bacteria Signup and view all the answers

What does therapeutic drug monitoring aim to achieve for some antibiotics?

Ensure they are therapeutic but not excessively toxic Signup and view all the answers

Which structure/process is disrupted by cell wall active agents in bacteria?

Peptidoglycan synthesis Signup and view all the answers

What is the mode of action of b-lactam antibiotics in bacteria?

Inhibiting transpeptidases Signup and view all the answers

Which type of bacteria can produce enzymes that destroy the b-lactam ring of antibiotics?

Both Gram-positive and Gram-negative bacteria Signup and view all the answers

What is the primary target of glycopeptides like vancomycin in bacteria?

Peptidoglycan synthesis Signup and view all the answers

Which enzyme is inhibited by b-lactam antibiotics in bacteria?

Transpeptidase Signup and view all the answers

What is the consequence of disrupting the process of peptidoglycan synthesis in bacterial cell walls?

Cell lysis Signup and view all the answers

Which type of bacteria are affected by glycopeptides like vancomycin?

Only Gram-positive bacteria Signup and view all the answers

What is the role of b-lactamase inhibitors in the presence of b-lactam antibiotics?

'Mop-up' b-lactamase enzymes Signup and view all the answers

'Transpeptidases' are enzymes involved in the:

"Cross-linking of peptidoglycan structure in bacterial cell walls" Signup and view all the answers

What is the primary target of glycopeptides like vancomycin in bacterial cells?

Peptidoglycan synthesis Signup and view all the answers

Mode of Action of Antimicrobials Quiz

Choose a study mode

Podcast

Questions and Answers

What is meant by selective toxicity in relation to antibiotics?

Why must antibiotics cause minimal harm to the host organism?

Which of the following is an essential requirement for antibiotics according to the text?

Why is it important for some antibiotics to have a narrow therapeutic index?

Which scenario represents selective toxicity in antibiotics?

What does therapeutic drug monitoring aim to achieve for some antibiotics?

Which structure/process is disrupted by cell wall active agents in bacteria?

What is the mode of action of b-lactam antibiotics in bacteria?

Which type of bacteria can produce enzymes that destroy the b-lactam ring of antibiotics?

What is the primary target of glycopeptides like vancomycin in bacteria?

Which enzyme is inhibited by b-lactam antibiotics in bacteria?

What is the consequence of disrupting the process of peptidoglycan synthesis in bacterial cell walls?

Which type of bacteria are affected by glycopeptides like vancomycin?

What is the role of b-lactamase inhibitors in the presence of b-lactam antibiotics?

'Transpeptidases' are enzymes involved in the:

What is the primary target of glycopeptides like vancomycin in bacterial cells?

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