Mitotic Abnormalities Overview
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Questions and Answers

Which type of mitotic abnormality occurs specifically during prophase?

  • Bridge in Anaphase
  • Sticky Metaphase
  • Lagging chromosomes
  • Despiralization (correct)
  • What phenomenon occurs during metaphase that can cause chromosomes to not align properly?

  • C-Metaphase (correct)
  • Un-oriented chromosomes
  • Sticky Metaphase (correct)
  • Micronuclei formation
  • Which of the following abnormalities is categorized under anaphase?

  • Despiralization
  • Micronuclei
  • Multipolar Anaphase (correct)
  • Multinuclei
  • Which abnormality is characterized by chromosomes that do not separate properly and can lead to extra nuclei?

    <p>Multinuclei</p> Signup and view all the answers

    What is a common environmental factor that contributes to the development of mitotic abnormalities?

    <p>Radiation</p> Signup and view all the answers

    Study Notes

    Mitotic Abnormalities

    • Mitotic abnormalities arise from environmental factors like radiation, chemicals, pesticides, or toxic agents.
    • The abnormalities manifest at different phases of mitosis.

    Types of Mitotic Abnormalities

    Prophase

    • Despiralization: Chromosomes fail to condense properly.

    Metaphase

    • C-Metaphase: Chromosomes fail to align at the metaphase plate.
    • Sticky Metaphase: Chromosomes stick together.

    Anaphase

    • Lagging chromosomes: Chromosomes fail to separate.
    • Sticky Anaphase: Chromosomes stick together during separation.
    • Bridge in Anaphase: Chromosomes fail to separate completely and leave a "bridge" of DNA.
    • Multipolar Anaphase: Multiple poles of spindle fibers form, pulling chromatids to multiple locations instead of two poles.

    Telophase

    • Un-oriented chromosome: Chromosomes do not move towards the poles and are unaligned.
    • Multinuclei: Multiple nuclei form in a cell due to improper cytokinesis.
    • Micronuclei: Small extra nuclei form within the cell.

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    Mitotic Abnormalities PDF

    Description

    Explore the various types of mitotic abnormalities that can occur due to environmental factors such as radiation and chemicals. This quiz covers the manifestations of these abnormalities at different phases of mitosis, including prophase, metaphase, anaphase, and telophase. Test your understanding of the complexities involved in cellular division and potential errors during the process.

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