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Questions and Answers
Which of the following is NOT an agent in the FOLFIRINOX regimen?
Which of the following is NOT an agent in the FOLFIRINOX regimen?
- Gemcitabine (correct)
- FOLinic acid
- OXaliplatin
- IRINotecan
What is the role of OXaliplatin in the FOLFIRINOX regimen?
What is the role of OXaliplatin in the FOLFIRINOX regimen?
- Detoxifying agent
- Topoisomerase inhibitor
- DNA-adduct forming agent (correct)
- None of the above
Why is FOLFIRINOX considered extremely toxic?
Why is FOLFIRINOX considered extremely toxic?
- The DNA-adduct forming property of OXaliplatin (correct)
- Due to the presence of IRINotecan
- It contains leucovorin (folinic acid)
- Its association with gemcitabine
In which type of cancer is FOLFIRINOX typically administered?
In which type of cancer is FOLFIRINOX typically administered?
What is the mechanism of action of IRINotecan in the FOLFIRINOX regimen?
What is the mechanism of action of IRINotecan in the FOLFIRINOX regimen?
Which publication introduced FOLFIRINOX or gemcitabine as adjuvant therapy for pancreatic cancer?
Which publication introduced FOLFIRINOX or gemcitabine as adjuvant therapy for pancreatic cancer?
What factor limits the administration of FOLFIRINOX to patients?
What factor limits the administration of FOLFIRINOX to patients?
Which agent in the FOLFIRINOX regimen is used as a detoxifying agent?
Which agent in the FOLFIRINOX regimen is used as a detoxifying agent?
'FOLFIRINOX' contains leucovorin. What is another name for leucovorin?
'FOLFIRINOX' contains leucovorin. What is another name for leucovorin?
'FOLFIRINOX' is a combination chemotherapy regimen used for the treatment of what type of cancer?
'FOLFIRINOX' is a combination chemotherapy regimen used for the treatment of what type of cancer?
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