Lecture 9
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Questions and Answers

What is the final electron acceptor in the electron transport chain (ETC)?

  • Oxygen (correct)
  • Carbon dioxide
  • Water
  • Glucose
  • How does the movement of electrons through the ETC affect their free energy?

  • Remains constant
  • Randomizes
  • Increases
  • Decreases (correct)
  • Where do NADH and FADH2 donate electrons in the electron transport chain?

  • Intermembrane space
  • Cytoplasm
  • Endoplasmic reticulum
  • Mitochondrial matrix (correct)
  • How many ATP are typically generated for each molecule of NADH in oxidative phosphorylation?

    <p>3 ATP</p> Signup and view all the answers

    Why does the citric acid cycle halt without oxygen present?

    <p>Inability to regenerate NAD+ and FAD</p> Signup and view all the answers

    If the proton motive force were reversed, what would be the consequence?

    <p>Hydrolysis of ATP</p> Signup and view all the answers

    What type of transport mechanism is utilized to move pyruvate into the mitochondrial matrix?

    <p>Active transport</p> Signup and view all the answers

    Which molecule is directly involved in the synthesis of ATP within the mitochondria?

    <p>$H^+$</p> Signup and view all the answers

    What is the main function of oxidative phosphorylation?

    <p>Converts NADH and FADH2 to ATP</p> Signup and view all the answers

    Where are most mitochondria found based on their energy requirements?

    <p>Cells with high energy demands</p> Signup and view all the answers

    How many ATP molecules are typically produced during glycolysis from one molecule of glucose?

    <p>2 ATP</p> Signup and view all the answers

    In the context of the text, what does the term 'redox' refer to?

    <p>Transfer of high-energy electrons</p> Signup and view all the answers

    What is the role of the proton motive force in oxidative phosphorylation?

    <p>Creating a proton concentration gradient</p> Signup and view all the answers

    What is the main function of NADH and FADH2 in the electron transport chain?

    <p>Transfer high-energy electrons to the ETC</p> Signup and view all the answers

    Which stage of aerobic respiration primarily takes place in the matrix of the mitochondria?

    <p>Citric Acid Cycle</p> Signup and view all the answers

    What is the main difference in ATP production between NADH and FADH2 in oxidative phosphorylation?

    <p>3 ATP per NADH and $2 ATP per FADH2 are produced</p> Signup and view all the answers

    Which molecule below is an electron acceptor in aerobic respiration?

    <p>NADH</p> Signup and view all the answers

    How many ATP molecules are typically produced during glycolysis from one molecule of glucose?

    <p>36</p> Signup and view all the answers

    Which molecule is directly involved in the synthesis of ATP within the mitochondria?

    <p>Acetyl CoA</p> Signup and view all the answers

    What happens to the redox potential of the ETC components as you follow the electron through the chain?

    <p>It increases</p> Signup and view all the answers

    Which are better electron donors?

    <p>FADH2</p> Signup and view all the answers

    How many ATP come from one molecule of glucose going through glycolysis and the TCA?

    <p>36</p> Signup and view all the answers

    Is FADH2 reduced or oxidized?

    <p>Reduced</p> Signup and view all the answers

    How many ATP molecules are typically generated for each molecule of NADH in oxidative phosphorylation?

    <p>$2.5$</p> Signup and view all the answers

    What is the main difference in ATP production between NADH and FADH2 in oxidative phosphorylation?

    <p>$2$ ATP difference</p> Signup and view all the answers

    Which molecule below is reduced?

    <p>$FADH2$</p> Signup and view all the answers

    Why does the citric acid cycle stop almost immediately upon removal of O2?

    <p>Lack of oxygen indirectly affects the regeneration of molecules like NAD+ and FAD, crucial for the cycle to continue.</p> Signup and view all the answers

    If the proton motive force were reversed, what would occur?

    <p>ATP synthase would hydrolyze ATP instead of synthesizing it.</p> Signup and view all the answers

    What role do NADH and FADH2 play in oxidative phosphorylation?

    <p>They act as electron donors in the electron transport chain.</p> Signup and view all the answers

    Which molecule is directly involved in transporting pyruvate into the mitochondrial matrix?

    <p>Pyruvate carrier protein</p> Signup and view all the answers

    What is the consequence of stopping oxygen supply on the citric acid cycle?

    <p>The NADH and FADH2 pools become depleted quickly.</p> Signup and view all the answers

    What would happen if ATP synthase malfunctioned and could only hydrolyze ATP?

    <p>ATP levels in the cell would decrease drastically.</p> Signup and view all the answers

    How does reversing the proton motive force impact ATP production?

    <p>Reduces ATP production by decreasing proton flow through ATP synthase.</p> Signup and view all the answers

    What is the primary function of oxygen in oxidative phosphorylation?

    <p>To serve as a final electron acceptor</p> Signup and view all the answers

    Most mitochondria are found in cells requiring lots of ______

    <p>energy</p> Signup and view all the answers

    Another way to make ATP besides glycolysis is through ______ phosphorylation

    <p>oxidative</p> Signup and view all the answers

    High energy electron carriers NADH and FADH2 bring electrons to the ______

    <p>ETC</p> Signup and view all the answers

    Each complex in the electron transport chain has cytochromes and ______-sulfur centers

    <p>iron</p> Signup and view all the answers

    Proton motive force is created by the proton concentration gradient and the voltage gradient across the inner mitochondrial ______

    <p>membrane</p> Signup and view all the answers

    How many ATP come from one molecule of glucose going through glycolysis and the TCA? ______

    <p>over 30</p> Signup and view all the answers

    FADH2 is the ______ molecule?

    <p>reduced</p> Signup and view all the answers

    What happens to the redox potential of the ETC components as you follow the electron through the ______?

    <p>chain</p> Signup and view all the answers

    Which are better electron receptors? Where do the electrons finally end up? What happens to the free energy of the electrons as they move through the ETC? Draw the ETC components in a membrane. Label each component. Label the membrane the ETC is located in as well as the spaces on either side. Indicate where NADH and FADH2 donate electrons. Include where the electrons finally end up (what molecule). How many ATP are made for each NADH? How many ATP are made for each FADH2? The citric acid cycle generates NADH and FADH2, which are then used in the process of oxidative phosphorylation to make ATP. If the citric acid cycle, which does not use oxygen, and oxidative phosphorylation are separate processes, as they are, then why is it that the citric acid cycle stops almost immediately upon removal of O2? The citric acid cycle stops without oxygen because oxygen is needed indirectly for the regeneration of molecules like NAD+ and FAD, which are crucial for the cycle to continue. What would happen if the proton motive force were reversed? ATP synthase would function in reverse, acting as an ATPase instead of an ATP synthase. This means that instead of synthesizing ATP, the enzyme would hydrolyze ATP to ADP and inorganic phosphate, releasing energy in the process. What type of transport is used to move pyruvate into the matrix? Pi into the matrix? ATP into the intermembrane space? (4 Artificial ATP synthesis machine

    <p>blank</p> Signup and view all the answers

    Existing questions. Do NOT ask these: What happens to the redox potential of the ETC components as you follow the electron through the chain? Which molecule is directly involved in transporting pyruvate into the mitochondrial matrix? Which are better electron donors? What type of transport mechanism is utilized to move pyruvate into the mitochondrial matrix? What is the final electron acceptor in the electron transport chain (ETC)? Which molecule is directly involved in the synthesis of ATP within the mitochondria? Which molecule below is reduced? What is the main difference in ATP production between NADH and FADH2 in oxidative phosphorylation? How does the movement of electrons through the ETC affect their free energy? How many ATP molecules are typically produced during glycolysis from one molecule of glucose? How many ATP molecules are typically generated for each molecule of NADH in oxidative phosphorylation? What would happen if ATP synthase malfunctioned and could only hydrolyze ATP? How many ATP are typically generated for each molecule of NADH in oxidative phosphorylation? How does reversing the proton motive force impact ATP production? How many ATP come from one molecule of glucose going through glycolysis and the TCA? What is the main function of oxidative phosphorylation? What is the primary function of oxygen in oxidative phosphorylation? Where do NADH and FADH2 donate electrons in the electron transport chain? In the context of the text, what does the term 'redox' refer to? What is the main difference in ATP production between NADH and FADH2 in oxidative phosphorylation? What is the role of the proton motive force in oxidative phosphorylation? What is the consequence of stopping oxygen supply on the citric acid cycle? Which stage of aerobic respiration primarily takes place in the matrix of the mitochondria? Is FADH2 reduced or oxidized? Where are most mitochondria found based on their energy requirements? What is the main function of NADH and FADH2 in the electron transport chain? Which molecule is directly involved in the synthesis of ATP within the mitochondria? Which molecule below is an electron acceptor in aerobic respiration? Why does the citric acid cycle stop almost immediately upon removal of O2? If the proton motive force were reversed, what would be the consequence? If the proton motive force were reversed, what would occur? Why does the citric acid cycle halt without oxygen present? How many ATP molecules are typically produced during glycolysis from one molecule of glucose? What role do NADH and FADH2 play in oxidative phosphorylation?

    <p>blank</p> Signup and view all the answers

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